Laser-induced Breakdown Spectroscopy (LIBS) as a diagnostics tool for biological tissue analysis
In this thesis, the emerging analytical technique laser‐induced breakdown spectroscopy(LIBS) is investigated as a diagnostic tool for biological tissues analysis. The two main objectives of the work are using LIBS to provide tissue type feedback information during laser surgery and to use LIBS as an...
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| Формат: | Online |
| Хэл сонгох: | англи |
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FAU University Press
2025
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| Нөхцлүүд: | |
| Онлайн хандалт: | ONIX_20251120T103930_9783961476428_17 |
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| _version_ | 1869518997844656128 |
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| author | Mehari, Fanuel |
| author_browse | Mehari, Fanuel |
| author_facet | Mehari, Fanuel |
| author_sort | Mehari, Fanuel |
| collection | Directory of Open Access Books |
| description | In this thesis, the emerging analytical technique laser‐induced breakdown spectroscopy(LIBS) is investigated as a diagnostic tool for biological tissues analysis. The two main objectives of the work are using LIBS to provide tissue type feedback information during laser surgery and to use LIBS as an imaging modality by mapping the distribution of elements in tissues. The viability of LIBS for the direct measurement of elements in biological tissue and indirect measurement of molecules has been presented. The applicability of LIBS for real‐time tissue classification to use it as a feedback control mechanism of clinical laser surgery systems has been demonstrated. High classification accuracy of different tissues has been achieved. The results of measuring the distribution of elements in tissues shows that LIBS can be a powerful imaging modality for medical applications that seek to understand the chemical microenvironment of tissues. This has been demonstrated by mapping the different distribution of certain elements between cancerous and healthy tissues. |
| format | Online |
| id | doab-20.500.12854ir-169052 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | FAU University Press |
| publisherStr | FAU University Press |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1690522025-11-22T05:22:31Z Laser-induced Breakdown Spectroscopy (LIBS) as a diagnostics tool for biological tissue analysis Mehari, Fanuel Cancer tissue characterization plasma properties Laser surgery feedback system Spectroscopy (LIBS) Tissue classification Laser‐induced Breakdown thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTB Applied optics::TTBL Laser technology and holography thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKS Medical imaging thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTW Assistive technology In this thesis, the emerging analytical technique laser‐induced breakdown spectroscopy(LIBS) is investigated as a diagnostic tool for biological tissues analysis. The two main objectives of the work are using LIBS to provide tissue type feedback information during laser surgery and to use LIBS as an imaging modality by mapping the distribution of elements in tissues. The viability of LIBS for the direct measurement of elements in biological tissue and indirect measurement of molecules has been presented. The applicability of LIBS for real‐time tissue classification to use it as a feedback control mechanism of clinical laser surgery systems has been demonstrated. High classification accuracy of different tissues has been achieved. The results of measuring the distribution of elements in tissues shows that LIBS can be a powerful imaging modality for medical applications that seek to understand the chemical microenvironment of tissues. This has been demonstrated by mapping the different distribution of certain elements between cancerous and healthy tissues. 2025-11-21T05:05:00Z 2025-11-21T05:05:00Z 2025-11-20T09:42:02Z 2023 book ONIX_20251120T103930_9783961476428_17 https://library.oapen.org/handle/20.500.12657/108288 9783961476428 9783961476411 https://directory.doabooks.org/handle/20.500.12854/169052 eng FAU Studien aus dem Maschinenbau open access image/jpeg Attribution-NonCommercial 4.0 International https://library.oapen.org/bitstream/20.500.12657/108288/1/9783961476428.pdf FAU University Press 10.25593/978-3-96147-642-8 10.25593/978-3-96147-642-8 2c600dea-eece-4066-87be-da335e323fdb 9783961476428 9783961476411 145 Erlangen open access |
| spellingShingle | Cancer tissue characterization plasma properties Laser surgery feedback system Spectroscopy (LIBS) Tissue classification Laser‐induced Breakdown thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTB Applied optics::TTBL Laser technology and holography thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKS Medical imaging thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTW Assistive technology Mehari, Fanuel Laser-induced Breakdown Spectroscopy (LIBS) as a diagnostics tool for biological tissue analysis |
| title | Laser-induced Breakdown Spectroscopy (LIBS) as a diagnostics tool for biological tissue analysis |
| title_full | Laser-induced Breakdown Spectroscopy (LIBS) as a diagnostics tool for biological tissue analysis |
| title_fullStr | Laser-induced Breakdown Spectroscopy (LIBS) as a diagnostics tool for biological tissue analysis |
| title_full_unstemmed | Laser-induced Breakdown Spectroscopy (LIBS) as a diagnostics tool for biological tissue analysis |
| title_short | Laser-induced Breakdown Spectroscopy (LIBS) as a diagnostics tool for biological tissue analysis |
| title_sort | laser induced breakdown spectroscopy libs as a diagnostics tool for biological tissue analysis |
| topic | Cancer tissue characterization plasma properties Laser surgery feedback system Spectroscopy (LIBS) Tissue classification Laser‐induced Breakdown thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTB Applied optics::TTBL Laser technology and holography thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKS Medical imaging thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTW Assistive technology |
| topic_facet | Cancer tissue characterization plasma properties Laser surgery feedback system Spectroscopy (LIBS) Tissue classification Laser‐induced Breakdown thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTB Applied optics::TTBL Laser technology and holography thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKS Medical imaging thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTW Assistive technology |
| url | ONIX_20251120T103930_9783961476428_17 |
| work_keys_str_mv | AT meharifanuel laserinducedbreakdownspectroscopylibsasadiagnosticstoolforbiologicaltissueanalysis |