Assessment of microcirculation by shifted position-diffuse reflectance imaging (SP-DRI)
Multiple diseases like diabetes mellitus, hypertension or autoimmune diseases may be associated with a wide spectrum of microvascular dysfunctions, microangiopathies and microcirculatory disorders. It can thus be assumed that monitoring the microcirculation could be useful to diagnose various local...
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| フォーマット: | Online |
| 言語: | 英語 |
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FAU University Press
2025
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| オンライン･アクセス: | ONIX_20251120T103930_9783961477609_41 |
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| _version_ | 1869529134530560000 |
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| author | Späth, Moritz |
| author_browse | Späth, Moritz |
| author_facet | Späth, Moritz |
| author_sort | Späth, Moritz |
| collection | Directory of Open Access Books |
| description | Multiple diseases like diabetes mellitus, hypertension or autoimmune diseases may be associated with a wide spectrum of microvascular dysfunctions, microangiopathies and microcirculatory disorders. It can thus be assumed that monitoring the microcirculation could be useful to diagnose various local and systemic circulatory disorders and could be used to monitor critically ill patients. A stand-alone measurement method that allows a reliable detection of impending or manifest local or systemic circulatory malfunctions would be of great value. In this context, shifted position-diffuse reflectance imaging (SP-DRI) offers a promising approach. It is an optical and thus non-invasive method based on the diffuse reflected light. In this doctoral thesis, the SP-DRI method is developed and presented and the algorithms behind it are explained in detail. The method is set in relation to already existing diagnostic approaches for the assessment of the microcirculatory function. The current state of research on SP-DRI is described along with an outline of the future potential of this imaging technique. The SP-DRI approach proved to be highly functional both simulatively and experimentally. Reliable information can be obtained in real time with an easy to implement setup. SP-DRI may thus be an important milestone on the way to early and conveniently diagnosing diseases associated with the constriction or dilation of the arterioles, venules or the capillary bed itself. |
| format | Online |
| id | doab-20.500.12854ir-169115 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | FAU University Press |
| publisherStr | FAU University Press |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1691152025-11-22T06:08:38Z Assessment of microcirculation by shifted position-diffuse reflectance imaging (SP-DRI) Späth, Moritz Reflexionsspektroskopie Maschinenbau SPDRI Produktionstechnik Diagnosing microvascular dysfunctions Capillaries Microcirculation Diagnose DRI Mikrozirkulation Monitoring system Monitoring Diffuse Reflexion Shifted position-diffuse reflectance imaging Diffuse reflectance Mikrozirkulationsstörung Diagnosis system Kapillare Ingenieurwissenschaften thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGB Mechanical engineering thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBG Medical equipment and techniques thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTB Applied optics Multiple diseases like diabetes mellitus, hypertension or autoimmune diseases may be associated with a wide spectrum of microvascular dysfunctions, microangiopathies and microcirculatory disorders. It can thus be assumed that monitoring the microcirculation could be useful to diagnose various local and systemic circulatory disorders and could be used to monitor critically ill patients. A stand-alone measurement method that allows a reliable detection of impending or manifest local or systemic circulatory malfunctions would be of great value. In this context, shifted position-diffuse reflectance imaging (SP-DRI) offers a promising approach. It is an optical and thus non-invasive method based on the diffuse reflected light. In this doctoral thesis, the SP-DRI method is developed and presented and the algorithms behind it are explained in detail. The method is set in relation to already existing diagnostic approaches for the assessment of the microcirculatory function. The current state of research on SP-DRI is described along with an outline of the future potential of this imaging technique. The SP-DRI approach proved to be highly functional both simulatively and experimentally. Reliable information can be obtained in real time with an easy to implement setup. SP-DRI may thus be an important milestone on the way to early and conveniently diagnosing diseases associated with the constriction or dilation of the arterioles, venules or the capillary bed itself. 2025-11-21T05:17:45Z 2025-11-21T05:17:45Z 2025-11-20T09:43:19Z 2024 book ONIX_20251120T103930_9783961477609_41 https://library.oapen.org/handle/20.500.12657/108312 9783961477609 9783961477593 https://directory.doabooks.org/handle/20.500.12854/169115 eng FAU Studien aus dem Maschinenbau open access image/jpeg Attribution-NonCommercial 4.0 International https://library.oapen.org/bitstream/20.500.12657/108312/1/9783961477609.pdf FAU University Press 10.25593/978-3-96147-760-9 10.25593/978-3-96147-760-9 2c600dea-eece-4066-87be-da335e323fdb 9783961477609 9783961477593 109 Erlangen open access |
| spellingShingle | Reflexionsspektroskopie Maschinenbau SPDRI Produktionstechnik Diagnosing microvascular dysfunctions Capillaries Microcirculation Diagnose DRI Mikrozirkulation Monitoring system Monitoring Diffuse Reflexion Shifted position-diffuse reflectance imaging Diffuse reflectance Mikrozirkulationsstörung Diagnosis system Kapillare Ingenieurwissenschaften thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGB Mechanical engineering thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBG Medical equipment and techniques thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTB Applied optics Späth, Moritz Assessment of microcirculation by shifted position-diffuse reflectance imaging (SP-DRI) |
| title | Assessment of microcirculation by shifted position-diffuse reflectance imaging (SP-DRI) |
| title_full | Assessment of microcirculation by shifted position-diffuse reflectance imaging (SP-DRI) |
| title_fullStr | Assessment of microcirculation by shifted position-diffuse reflectance imaging (SP-DRI) |
| title_full_unstemmed | Assessment of microcirculation by shifted position-diffuse reflectance imaging (SP-DRI) |
| title_short | Assessment of microcirculation by shifted position-diffuse reflectance imaging (SP-DRI) |
| title_sort | assessment of microcirculation by shifted position diffuse reflectance imaging sp dri |
| topic | Reflexionsspektroskopie Maschinenbau SPDRI Produktionstechnik Diagnosing microvascular dysfunctions Capillaries Microcirculation Diagnose DRI Mikrozirkulation Monitoring system Monitoring Diffuse Reflexion Shifted position-diffuse reflectance imaging Diffuse reflectance Mikrozirkulationsstörung Diagnosis system Kapillare Ingenieurwissenschaften thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGB Mechanical engineering thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBG Medical equipment and techniques thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTB Applied optics |
| topic_facet | Reflexionsspektroskopie Maschinenbau SPDRI Produktionstechnik Diagnosing microvascular dysfunctions Capillaries Microcirculation Diagnose DRI Mikrozirkulation Monitoring system Monitoring Diffuse Reflexion Shifted position-diffuse reflectance imaging Diffuse reflectance Mikrozirkulationsstörung Diagnosis system Kapillare Ingenieurwissenschaften thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGB Mechanical engineering thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBG Medical equipment and techniques thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTB Applied optics |
| url | ONIX_20251120T103930_9783961477609_41 |
| work_keys_str_mv | AT spathmoritz assessmentofmicrocirculationbyshiftedpositiondiffusereflectanceimagingspdri |