Electrical Brain Stimulation: Mechanisms and Modulation of Neuronal Activity

This open access book explores the mechanisms and modulation of invasive neural electrical stimulation in the brain. Drawing from the author's extensive research experience, it offers in-depth yet accessible content, enriched with vivid illustrations and practical applications. Notably, the book pro...

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Autor principal: Feng, Zhouyan
Formato: Online
Idioma:inglês
Publicado em: Springer Nature 2025
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Acesso em linha:ONIX_20251218T100927_9789819541454_44
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author Feng, Zhouyan
author_browse Feng, Zhouyan
author_facet Feng, Zhouyan
author_sort Feng, Zhouyan
collection Directory of Open Access Books
description This open access book explores the mechanisms and modulation of invasive neural electrical stimulation in the brain. Drawing from the author's extensive research experience, it offers in-depth yet accessible content, enriched with vivid illustrations and practical applications. Notably, the book provides detailed techniques for animal experiments and methods for recording and processing neural electrical signals with a depth rare in similar works. The book is divided into two parts. Part I introduces fundamental electrophysiological theories and experimental methods. It covers the basic electrical properties of neuronal membranes, the famous Hodgkin-Huxley mathematical model, hippocampal neural networks and electrically evoked potentials, in-vivo rat experimental methods and equipment, and techniques for recording and processing neural electrical signals. Part II focuses on neural modulation through various electrical stimulations. It examines how various patterns of high-frequency pulse stimulations affect individual neurons, neuronal populations, and neural networks. In addition to exploring neuronal responses to electrical stimulation under normal physiological conditions, this part also investigates the inhibitory effects of high-frequency stimulation on epileptiform activity. This comprehensive book can serve as a valuable reference for researchers, teachers, students, and enthusiasts in the fields of neurophysiology, neural signal analysis, neural engineering, neuromodulation, brain stimulation, and brain-computer interfaces. It also provides excellent supplementary material for undergraduate and graduate courses in biomedical signal processing, neural engineering, and neuroscience.
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spelling doab-20.500.12854ir-1704942025-12-22T05:34:31Z Electrical Brain Stimulation: Mechanisms and Modulation of Neuronal Activity Feng, Zhouyan Open Access Brain stimulation Neural modulation Deep brain stimulation Brain-computer interfaces High-frequency stimulation Neural engineering Neural signal processing In-vivo rat experiment Axonal block Unit spike Population spike Evoked potential Local field potential Hippocampus Non-linear Neuronal Firing Desynchronization Effect of High-Frequency Stimulation Pyramidal neuron Interneuron thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQW Biomedical engineering thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TH Energy technology and engineering::THR Electrical engineering thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences This open access book explores the mechanisms and modulation of invasive neural electrical stimulation in the brain. Drawing from the author's extensive research experience, it offers in-depth yet accessible content, enriched with vivid illustrations and practical applications. Notably, the book provides detailed techniques for animal experiments and methods for recording and processing neural electrical signals with a depth rare in similar works. The book is divided into two parts. Part I introduces fundamental electrophysiological theories and experimental methods. It covers the basic electrical properties of neuronal membranes, the famous Hodgkin-Huxley mathematical model, hippocampal neural networks and electrically evoked potentials, in-vivo rat experimental methods and equipment, and techniques for recording and processing neural electrical signals. Part II focuses on neural modulation through various electrical stimulations. It examines how various patterns of high-frequency pulse stimulations affect individual neurons, neuronal populations, and neural networks. In addition to exploring neuronal responses to electrical stimulation under normal physiological conditions, this part also investigates the inhibitory effects of high-frequency stimulation on epileptiform activity. This comprehensive book can serve as a valuable reference for researchers, teachers, students, and enthusiasts in the fields of neurophysiology, neural signal analysis, neural engineering, neuromodulation, brain stimulation, and brain-computer interfaces. It also provides excellent supplementary material for undergraduate and graduate courses in biomedical signal processing, neural engineering, and neuroscience. 2025-12-22T05:34:30Z 2025-12-22T05:34:30Z 2025-12-18T09:16:13Z 2026 book ONIX_20251218T100927_9789819541454_44 https://library.oapen.org/handle/20.500.12657/109317 9789819541454 9789819541447 https://directory.doabooks.org/handle/20.500.12854/170494 eng Engineering; Engineering (R0) open access image/jpeg n/a https://library.oapen.org/bitstream/20.500.12657/109317/1/9789819541454.pdf Springer Nature Springer 10.1007/978-981-95-4145-4 10.1007/978-981-95-4145-4 9fa3421d-f917-4153-b9ab-fc337c396b5a 9cdf5cb9-2405-4a80-ab0e-bce2dfd5e63e 219cc0eb-31a9-46a1-a50f-c2d756c7fec1 9789819541454 9789819541447 Springer 376 Singapore [...] National Natural Science Foundation of China Chinese National Science Foundation 10.13039/501100001809 open access
spellingShingle Open Access
Brain stimulation
Neural modulation
Deep brain stimulation
Brain-computer interfaces
High-frequency stimulation
Neural engineering
Neural signal processing
In-vivo rat experiment
Axonal block
Unit spike
Population spike
Evoked potential
Local field potential
Hippocampus
Non-linear Neuronal Firing
Desynchronization Effect of High-Frequency Stimulation
Pyramidal neuron
Interneuron
thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQW Biomedical engineering
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TH Energy technology and engineering::THR Electrical engineering
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
Feng, Zhouyan
Electrical Brain Stimulation: Mechanisms and Modulation of Neuronal Activity
title Electrical Brain Stimulation: Mechanisms and Modulation of Neuronal Activity
title_full Electrical Brain Stimulation: Mechanisms and Modulation of Neuronal Activity
title_fullStr Electrical Brain Stimulation: Mechanisms and Modulation of Neuronal Activity
title_full_unstemmed Electrical Brain Stimulation: Mechanisms and Modulation of Neuronal Activity
title_short Electrical Brain Stimulation: Mechanisms and Modulation of Neuronal Activity
title_sort electrical brain stimulation mechanisms and modulation of neuronal activity
topic Open Access
Brain stimulation
Neural modulation
Deep brain stimulation
Brain-computer interfaces
High-frequency stimulation
Neural engineering
Neural signal processing
In-vivo rat experiment
Axonal block
Unit spike
Population spike
Evoked potential
Local field potential
Hippocampus
Non-linear Neuronal Firing
Desynchronization Effect of High-Frequency Stimulation
Pyramidal neuron
Interneuron
thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQW Biomedical engineering
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TH Energy technology and engineering::THR Electrical engineering
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
topic_facet Open Access
Brain stimulation
Neural modulation
Deep brain stimulation
Brain-computer interfaces
High-frequency stimulation
Neural engineering
Neural signal processing
In-vivo rat experiment
Axonal block
Unit spike
Population spike
Evoked potential
Local field potential
Hippocampus
Non-linear Neuronal Firing
Desynchronization Effect of High-Frequency Stimulation
Pyramidal neuron
Interneuron
thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQW Biomedical engineering
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TH Energy technology and engineering::THR Electrical engineering
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
url ONIX_20251218T100927_9789819541454_44
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