Differential Diagnosis of Central Nervous System Demyelinating Diseases: A Comprehensive Clinical Guide

The differential diagnosis of demyelinating disease has grown considerably more demanding over the past two decades. The identification of AQP4-IgG and MOG-IgG as disease-specific antibodies reshaped what was once a relatively binary diagnostic landscape, and the list of conditions that can convinci...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Tunç, Abdulkadir, Reyes-Mantill, Maria I, Casallas-Vanegas, Adriana, Galvis-Palomino, Valentina, Boldrini, Vinícius, Zarco, Luis Alfonso, Contentti, Edgar Carnero, Becker, Jefferson, Sıvacı, Ali Özhan, Costa, Gloria Dalla, Szejko, Natalia, Sarıdaş, Furkan, Koç, Emine Rabia, Baydar, Caner, Jiménez-Ruiz, Amado, Gómez-Figueroa, Enrique, Orozco-Puga, Patricia, Vázquez, Patricia Corona, Ruiz-Sandoval, José Luis, Gluscevic, Sanja, Saramak, Kamila, Camera, Valentina
التنسيق: Online
اللغة:الإنجليزية
منشور في: Sakarya Üniversitesi Yayınları 2026
الموضوعات:
الوصول للمادة أونلاين:https://directory.doabooks.org/handle/20.500.12854/174382
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الوصف
الملخص:The differential diagnosis of demyelinating disease has grown considerably more demanding over the past two decades. The identification of AQP4-IgG and MOG-IgG as disease-specific antibodies reshaped what was once a relatively binary diagnostic landscape, and the list of conditions that can convincingly mimic multiple sclerosis—on MRI, in the CSF, and at the bedside—has never been longer. This book was written in response to that clinical reality. Neurologists from across Europe, Latin America, and beyond have contributed chapters that move systematically through the full differential: from MS, NMOSD, and MOGAD to vasculitides, leukodystrophies, infectious causes, toxic and nutritional disorders, and hereditary small vessel diseases. The emphasis throughout is practical—on the findings that guide diagnosis, the red flags that should prompt reconsideration, and the errors that carry the highest cost for patients. Designed for subspecialists and senior clinicians, it is a reference to return to when the diagnosis is not straightforward.