Acute and Chronic Heart Failure
The topic “Acute and Chronic Heart Failure: Pathophysiology and New Therapeutic Developments” was chosen because, despite the progress made in recent decades in the prevention and treatment of cardiovascular diseases, they remain the leading cause of death in both developed and developing countries,...
Αποθηκεύτηκε σε:
| Μορφή: | Online |
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| Γλώσσα: | Αγγλικά |
| Έκδοση: |
MDPI - Multidisciplinary Digital Publishing Institute
2026
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| Θέματα: | |
| Διαθέσιμο Online: | ONIX_20260416T142754_9783725852314_8 |
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| _version_ | 1869527625922248704 |
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| collection | Directory of Open Access Books |
| description | The topic “Acute and Chronic Heart Failure: Pathophysiology and New Therapeutic Developments” was chosen because, despite the progress made in recent decades in the prevention and treatment of cardiovascular diseases, they remain the leading cause of death in both developed and developing countries, and heart failure (HF) is, in any case, the endpoint of the majority of cardiac pathologies. HF prevalence is progressively increasing worldwide, with HF with preserved ejection fraction (HFpEF) now exceeding 50% prevalence in HF cases. The published contributions are numerous and all are interesting. I would, however, like to emphasize the fact that a rapidly growing condition worldwide—insulin resistance with associated hyperinsulinemia—that is present in a large proportion of HF patients, particularly in HF patients with preserved or only slightly reduced ejection fraction, is still not treated as an independent risk factor, despite the large body of the literature demonstrating its role in numerous significant metabolic and cardiovascular abnormalities. Patients with insulin resistance, which will later progress to type 2 diabetes, may, over time, develop pathological remodeling of the left ventricle with, initially, diastolic dysfunction and, subsequently, also systolic dysfunction, which will lead to the development of HF. |
| format | Online |
| id | doab-20.500.12854ir-174703 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2026 |
| publishDateRange | 2026 |
| publishDateSort | 2026 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1747032026-04-16T16:02:09Z Acute and Chronic Heart Failure Fazio, Serafino Mercurio, Valentina Heart failure Pulmonary arterial hypertension Pathophysiological novelties Treatment advances thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general The topic “Acute and Chronic Heart Failure: Pathophysiology and New Therapeutic Developments” was chosen because, despite the progress made in recent decades in the prevention and treatment of cardiovascular diseases, they remain the leading cause of death in both developed and developing countries, and heart failure (HF) is, in any case, the endpoint of the majority of cardiac pathologies. HF prevalence is progressively increasing worldwide, with HF with preserved ejection fraction (HFpEF) now exceeding 50% prevalence in HF cases. The published contributions are numerous and all are interesting. I would, however, like to emphasize the fact that a rapidly growing condition worldwide—insulin resistance with associated hyperinsulinemia—that is present in a large proportion of HF patients, particularly in HF patients with preserved or only slightly reduced ejection fraction, is still not treated as an independent risk factor, despite the large body of the literature demonstrating its role in numerous significant metabolic and cardiovascular abnormalities. Patients with insulin resistance, which will later progress to type 2 diabetes, may, over time, develop pathological remodeling of the left ventricle with, initially, diastolic dysfunction and, subsequently, also systolic dysfunction, which will lead to the development of HF. 2026-04-16T16:02:07Z 2026-04-16T16:02:07Z 2025 book ONIX_20260416T142754_9783725852314_8 9783725852314 9783725852321 https://directory.doabooks.org/handle/20.500.12854/174703 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/ https://mdpi.com/books/pdfview/book/11578 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-5232-1 10.3390/books978-3-7258-5232-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725852314 9783725852321 128 CH open access |
| spellingShingle | Heart failure Pulmonary arterial hypertension Pathophysiological novelties Treatment advances thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general Acute and Chronic Heart Failure |
| title | Acute and Chronic Heart Failure |
| title_full | Acute and Chronic Heart Failure |
| title_fullStr | Acute and Chronic Heart Failure |
| title_full_unstemmed | Acute and Chronic Heart Failure |
| title_short | Acute and Chronic Heart Failure |
| title_sort | acute and chronic heart failure |
| topic | Heart failure Pulmonary arterial hypertension Pathophysiological novelties Treatment advances thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general |
| topic_facet | Heart failure Pulmonary arterial hypertension Pathophysiological novelties Treatment advances thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general |
| url | ONIX_20260416T142754_9783725852314_8 |