Genomic Characterization of Antimicrobial Resistance and Evolution Mechanism of Bacteria

In the ever-evolving battle against antimicrobial resistance (AMR), our understanding of the genomic landscape of bacteria and their mechanisms of evolution has become pivotal. In bacteria, resistance to antibiotics is determined by genetic factors such as chromosomes, plasmids or other movable gene...

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Publicado: MDPI - Multidisciplinary Digital Publishing Institute 2026
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description In the ever-evolving battle against antimicrobial resistance (AMR), our understanding of the genomic landscape of bacteria and their mechanisms of evolution has become pivotal. In bacteria, resistance to antibiotics is determined by genetic factors such as chromosomes, plasmids or other movable genetic elements. Although antimicrobial resistance genes (ARGs) typically exhibit significant sequence variability, such as the impact of different concentrations of antibiotics on their genomic dynamics, the impact of this diversity on AMR is still unclear. Therefore, understanding the dynamic changes and mobilization of antibiotic resistance genes in humans, animals, plants and environmental microorganisms through genomics and metagenomics methods is crucial. This Special Issue seeks to foster a comprehensive understanding of the genetic underpinnings of bacterial antimicrobial resistance and the evolutionary dynamics that underlie these adaptations.
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publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-1747412026-04-16T16:09:35Z Genomic Characterization of Antimicrobial Resistance and Evolution Mechanism of Bacteria Amoako, Daniel Gyamfi Bester, Linda Antimicrobial resistance mechanism Mobile genetic element Horizontal gene transfer Resistome Evolution Molecular phylogenetics Genomics Bioinformatics analysis Next-generation sequencing thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences In the ever-evolving battle against antimicrobial resistance (AMR), our understanding of the genomic landscape of bacteria and their mechanisms of evolution has become pivotal. In bacteria, resistance to antibiotics is determined by genetic factors such as chromosomes, plasmids or other movable genetic elements. Although antimicrobial resistance genes (ARGs) typically exhibit significant sequence variability, such as the impact of different concentrations of antibiotics on their genomic dynamics, the impact of this diversity on AMR is still unclear. Therefore, understanding the dynamic changes and mobilization of antibiotic resistance genes in humans, animals, plants and environmental microorganisms through genomics and metagenomics methods is crucial. This Special Issue seeks to foster a comprehensive understanding of the genetic underpinnings of bacterial antimicrobial resistance and the evolutionary dynamics that underlie these adaptations. 2026-04-16T16:09:26Z 2026-04-16T16:09:26Z 2025 book ONIX_20260416T142754_9783725853076_46 9783725853076 9783725853083 https://directory.doabooks.org/handle/20.500.12854/174741 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/ https://mdpi.com/books/pdfview/book/11618 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-5308-3 10.3390/books978-3-7258-5308-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725853076 9783725853083 200 CH open access
spellingShingle Antimicrobial resistance mechanism
Mobile genetic element
Horizontal gene transfer
Resistome
Evolution
Molecular phylogenetics
Genomics
Bioinformatics analysis
Next-generation sequencing
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Genomic Characterization of Antimicrobial Resistance and Evolution Mechanism of Bacteria
title Genomic Characterization of Antimicrobial Resistance and Evolution Mechanism of Bacteria
title_full Genomic Characterization of Antimicrobial Resistance and Evolution Mechanism of Bacteria
title_fullStr Genomic Characterization of Antimicrobial Resistance and Evolution Mechanism of Bacteria
title_full_unstemmed Genomic Characterization of Antimicrobial Resistance and Evolution Mechanism of Bacteria
title_short Genomic Characterization of Antimicrobial Resistance and Evolution Mechanism of Bacteria
title_sort genomic characterization of antimicrobial resistance and evolution mechanism of bacteria
topic Antimicrobial resistance mechanism
Mobile genetic element
Horizontal gene transfer
Resistome
Evolution
Molecular phylogenetics
Genomics
Bioinformatics analysis
Next-generation sequencing
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet Antimicrobial resistance mechanism
Mobile genetic element
Horizontal gene transfer
Resistome
Evolution
Molecular phylogenetics
Genomics
Bioinformatics analysis
Next-generation sequencing
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url ONIX_20260416T142754_9783725853076_46