Cellular and Molecular Mechanisms in Gynecological Disorders
Gynecological disorders encompass a broad spectrum of conditions affecting the female reproductive organs, including the uterus, ovaries, fallopian tubes, cervix, vagina, and external genitalia. These diseases impose a major health and financial burden worldwide, causing significant morbidity and pr...
Sábháilte in:
| Formáid: | Online |
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| Teanga: | Béarla |
| Foilsithe / Cruthaithe: |
MDPI - Multidisciplinary Digital Publishing Institute
2026
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| Ábhair: | |
| Rochtain ar líne: | ONIX_20260416T142754_9783725854134_43 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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| _version_ | 1869523638190866432 |
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| collection | Directory of Open Access Books |
| description | Gynecological disorders encompass a broad spectrum of conditions affecting the female reproductive organs, including the uterus, ovaries, fallopian tubes, cervix, vagina, and external genitalia. These diseases impose a major health and financial burden worldwide, causing significant morbidity and profoundly affecting women’s quality of life. Despite their prevalence, the underlying etiologies are often complex and remain only partially understood, with limited knowledge of the risk factors that contribute to disease onset and progression. Advancing our understanding of the cellular and molecular mechanisms driving these disorders is therefore essential for developing more effective strategies for prevention, diagnosis, and treatment. This collection of original research and review articles provides a comprehensive overview of emerging insights into ovarian and uterine pathologies, reflecting the interconnected nature of gynecologic conditions. Topics addressed include mesothelial clearance by endometriosis spheroids, impaired decidualization, autophagy in reproductive aging, protease regulation in ovarian function, immune–tumor interactions in ovarian cancer, and the molecular drivers of fibrosis, senescence, cellular transformation, and tumorigenesis in uterine tissues. Collectively, these contributions underscore the urgent need for integrative research efforts that bridge basic science and clinical application, ultimately advancing the field toward improved outcomes for women affected by gynecologic diseases. |
| format | Online |
| id | doab-20.500.12854ir-174788 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2026 |
| publishDateRange | 2026 |
| publishDateSort | 2026 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1747882026-04-16T16:24:59Z Cellular and Molecular Mechanisms in Gynecological Disorders Yang, Qiwei Uterus Ovary Endometriosis Leiomyoma Uterine cancer Ovarian cancer Polycystic ovary syndrome Primary ovarian insufficiency Female infertility Aging Biomarkers Pathways Transcriptome Proteomics Epigenome Gynecological disorders thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Gynecological disorders encompass a broad spectrum of conditions affecting the female reproductive organs, including the uterus, ovaries, fallopian tubes, cervix, vagina, and external genitalia. These diseases impose a major health and financial burden worldwide, causing significant morbidity and profoundly affecting women’s quality of life. Despite their prevalence, the underlying etiologies are often complex and remain only partially understood, with limited knowledge of the risk factors that contribute to disease onset and progression. Advancing our understanding of the cellular and molecular mechanisms driving these disorders is therefore essential for developing more effective strategies for prevention, diagnosis, and treatment. This collection of original research and review articles provides a comprehensive overview of emerging insights into ovarian and uterine pathologies, reflecting the interconnected nature of gynecologic conditions. Topics addressed include mesothelial clearance by endometriosis spheroids, impaired decidualization, autophagy in reproductive aging, protease regulation in ovarian function, immune–tumor interactions in ovarian cancer, and the molecular drivers of fibrosis, senescence, cellular transformation, and tumorigenesis in uterine tissues. Collectively, these contributions underscore the urgent need for integrative research efforts that bridge basic science and clinical application, ultimately advancing the field toward improved outcomes for women affected by gynecologic diseases. 2026-04-16T16:24:52Z 2026-04-16T16:24:52Z 2025 book ONIX_20260416T142754_9783725854134_43 9783725854134 9783725854141 https://directory.doabooks.org/handle/20.500.12854/174788 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/ https://mdpi.com/books/pdfview/book/11667 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-5414-1 10.3390/books978-3-7258-5414-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725854134 9783725854141 376 CH open access |
| spellingShingle | Uterus Ovary Endometriosis Leiomyoma Uterine cancer Ovarian cancer Polycystic ovary syndrome Primary ovarian insufficiency Female infertility Aging Biomarkers Pathways Transcriptome Proteomics Epigenome Gynecological disorders thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Cellular and Molecular Mechanisms in Gynecological Disorders |
| title | Cellular and Molecular Mechanisms in Gynecological Disorders |
| title_full | Cellular and Molecular Mechanisms in Gynecological Disorders |
| title_fullStr | Cellular and Molecular Mechanisms in Gynecological Disorders |
| title_full_unstemmed | Cellular and Molecular Mechanisms in Gynecological Disorders |
| title_short | Cellular and Molecular Mechanisms in Gynecological Disorders |
| title_sort | cellular and molecular mechanisms in gynecological disorders |
| topic | Uterus Ovary Endometriosis Leiomyoma Uterine cancer Ovarian cancer Polycystic ovary syndrome Primary ovarian insufficiency Female infertility Aging Biomarkers Pathways Transcriptome Proteomics Epigenome Gynecological disorders thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | Uterus Ovary Endometriosis Leiomyoma Uterine cancer Ovarian cancer Polycystic ovary syndrome Primary ovarian insufficiency Female infertility Aging Biomarkers Pathways Transcriptome Proteomics Epigenome Gynecological disorders thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20260416T142754_9783725854134_43 |