Human Poliovirus
Polio eradication is the global effort to permanently eliminate poliovirus and the disease it causes, poliomyelitis. The Global Polio Eradication Initiative (GPEI) leads this effort.While wild poliovirus cases decreasing by over 99% since 1988, the job is not yet finished. Key aspects of polio eradi...
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| Format: | Online |
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| Language: | English |
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MDPI - Multidisciplinary Digital Publishing Institute
2026
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| Online Access: | ONIX_20260416T142754_9783725855278_19 |
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| description | Polio eradication is the global effort to permanently eliminate poliovirus and the disease it causes, poliomyelitis. The Global Polio Eradication Initiative (GPEI) leads this effort.While wild poliovirus cases decreasing by over 99% since 1988, the job is not yet finished. Key aspects of polio eradication include the following: Ensuring high immunization coverage with oral polio vaccine (OPV) and inactivated polio vaccine (IPV). Robust surveillance systems, including acute flaccid paralysis surveillance to detect and respond to poliovirus circulation. Assuring polioviruses are not stored in laboratories. Rapid and effective responses to outbreaks, including vaccination campaigns. Significant funding from various sources. Only Pakistan and Afghanistan remain endemic for wild poliovirus. Two of the three wild poliovirus serotypes (Types 2 and 3) have been certified as eradicated. The Goal of Polio Eradication: Achieve a world free of all forms of poliovirus, including both wild and vaccine-derived strains. |
| format | Online |
| id | doab-20.500.12854ir-174864 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2026 |
| publishDateRange | 2026 |
| publishDateSort | 2026 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1748642026-04-16T17:03:59Z Human Poliovirus McKinlay, Mark A. Orenstein, Walter A. Polio GAPIII Poliovirus containment NAC Poliovirus-essential facility PEF Eradication Immunity Herd immunity Vaccination Polio eradication Zero dose Immunization Integrated interventions Conflict-affected Health systems Inactivated poliovirus vaccine (IPV) Global Polio Eradication Initiative (GPEI) Mucosal immunity Fractional-dose IPV (fIPV) Poliovirus Novel oral poliovirus vaccine Emergency use listing WHO prequalification Vaccine Public health emergency of international concern Poliomyelitis Global Polio Eradication Initiative Outbreak response Vaccine-derived poliovirus Partnership Surveillance Campaign Children Modeling Policy Decision Dynamic modeling OPV cessation Immunodeficiency-associated vaccine-derived poliovirus Picornavirus Antiviral development Small molecule-based antiviral drug Capsid-binding agent Molecular external quality assessment Nucleic acid testing World Health Organization Quality assurance program Accreditation Proficiency panel testing Immunodeficiency disorders Vaccine-associated paralytic poliomyelitis thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNS Epidemiology and Medical statistics Polio eradication is the global effort to permanently eliminate poliovirus and the disease it causes, poliomyelitis. The Global Polio Eradication Initiative (GPEI) leads this effort.While wild poliovirus cases decreasing by over 99% since 1988, the job is not yet finished. Key aspects of polio eradication include the following: Ensuring high immunization coverage with oral polio vaccine (OPV) and inactivated polio vaccine (IPV). Robust surveillance systems, including acute flaccid paralysis surveillance to detect and respond to poliovirus circulation. Assuring polioviruses are not stored in laboratories. Rapid and effective responses to outbreaks, including vaccination campaigns. Significant funding from various sources. Only Pakistan and Afghanistan remain endemic for wild poliovirus. Two of the three wild poliovirus serotypes (Types 2 and 3) have been certified as eradicated. The Goal of Polio Eradication: Achieve a world free of all forms of poliovirus, including both wild and vaccine-derived strains. 2026-04-16T17:03:50Z 2026-04-16T17:03:50Z 2025 book ONIX_20260416T142754_9783725855278_19 9783725855278 9783725855285 https://directory.doabooks.org/handle/20.500.12854/174864 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/ https://mdpi.com/books/pdfview/book/11745 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-5528-5 10.3390/books978-3-7258-5528-5 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725855278 9783725855285 196 CH open access |
| spellingShingle | Polio GAPIII Poliovirus containment NAC Poliovirus-essential facility PEF Eradication Immunity Herd immunity Vaccination Polio eradication Zero dose Immunization Integrated interventions Conflict-affected Health systems Inactivated poliovirus vaccine (IPV) Global Polio Eradication Initiative (GPEI) Mucosal immunity Fractional-dose IPV (fIPV) Poliovirus Novel oral poliovirus vaccine Emergency use listing WHO prequalification Vaccine Public health emergency of international concern Poliomyelitis Global Polio Eradication Initiative Outbreak response Vaccine-derived poliovirus Partnership Surveillance Campaign Children Modeling Policy Decision Dynamic modeling OPV cessation Immunodeficiency-associated vaccine-derived poliovirus Picornavirus Antiviral development Small molecule-based antiviral drug Capsid-binding agent Molecular external quality assessment Nucleic acid testing World Health Organization Quality assurance program Accreditation Proficiency panel testing Immunodeficiency disorders Vaccine-associated paralytic poliomyelitis thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNS Epidemiology and Medical statistics Human Poliovirus |
| title | Human Poliovirus |
| title_full | Human Poliovirus |
| title_fullStr | Human Poliovirus |
| title_full_unstemmed | Human Poliovirus |
| title_short | Human Poliovirus |
| title_sort | human poliovirus |
| topic | Polio GAPIII Poliovirus containment NAC Poliovirus-essential facility PEF Eradication Immunity Herd immunity Vaccination Polio eradication Zero dose Immunization Integrated interventions Conflict-affected Health systems Inactivated poliovirus vaccine (IPV) Global Polio Eradication Initiative (GPEI) Mucosal immunity Fractional-dose IPV (fIPV) Poliovirus Novel oral poliovirus vaccine Emergency use listing WHO prequalification Vaccine Public health emergency of international concern Poliomyelitis Global Polio Eradication Initiative Outbreak response Vaccine-derived poliovirus Partnership Surveillance Campaign Children Modeling Policy Decision Dynamic modeling OPV cessation Immunodeficiency-associated vaccine-derived poliovirus Picornavirus Antiviral development Small molecule-based antiviral drug Capsid-binding agent Molecular external quality assessment Nucleic acid testing World Health Organization Quality assurance program Accreditation Proficiency panel testing Immunodeficiency disorders Vaccine-associated paralytic poliomyelitis thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNS Epidemiology and Medical statistics |
| topic_facet | Polio GAPIII Poliovirus containment NAC Poliovirus-essential facility PEF Eradication Immunity Herd immunity Vaccination Polio eradication Zero dose Immunization Integrated interventions Conflict-affected Health systems Inactivated poliovirus vaccine (IPV) Global Polio Eradication Initiative (GPEI) Mucosal immunity Fractional-dose IPV (fIPV) Poliovirus Novel oral poliovirus vaccine Emergency use listing WHO prequalification Vaccine Public health emergency of international concern Poliomyelitis Global Polio Eradication Initiative Outbreak response Vaccine-derived poliovirus Partnership Surveillance Campaign Children Modeling Policy Decision Dynamic modeling OPV cessation Immunodeficiency-associated vaccine-derived poliovirus Picornavirus Antiviral development Small molecule-based antiviral drug Capsid-binding agent Molecular external quality assessment Nucleic acid testing World Health Organization Quality assurance program Accreditation Proficiency panel testing Immunodeficiency disorders Vaccine-associated paralytic poliomyelitis thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNS Epidemiology and Medical statistics |
| url | ONIX_20260416T142754_9783725855278_19 |