Toxicity and Human Health Assessment of Air Pollutants
Air pollution has been shown to be responsible for the morbidity and mortality of a variety of major diseases. The World Health Organization (WHO) estimates that almost the whole global population breathes air that exceeds WHO guidelines and contains high levels of pollutants. To date, however, the...
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| Μορφή: | Online |
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| Γλώσσα: | Αγγλικά |
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MDPI - Multidisciplinary Digital Publishing Institute
2026
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| Διαθέσιμο Online: | ONIX_20260416T142754_9783725856770_29 |
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| collection | Directory of Open Access Books |
| description | Air pollution has been shown to be responsible for the morbidity and mortality of a variety of major diseases. The World Health Organization (WHO) estimates that almost the whole global population breathes air that exceeds WHO guidelines and contains high levels of pollutants. To date, however, the key constituents of air pollution which impact health and the potential mechanisms remain largely unstudied. In addition, comprehensive assessments of evidence from in vitro and in vivo studies, high-quality cohort studies, and high-resolution model simulations of health impacts are still substantially sparse. Hence, assessing the health risks, identifying the toxic effects, and elucidating the underlying mechanisms are of great importance. This Reprint aims to understand the mechanisms of the health effects caused by air pollution and ensure accurate exposure assessments around ambient environments and inside human bodies, including a range of approaches—from epidemiological cohorts and toxicological studies—to elucidate the linkage between air pollutant exposure and the mechanisms related to health effects. The articles published in this Special Issue can be categorized into four main research directions: elucidating underlying toxicity mechanisms, identifying critical exposure windows and vulnerable populations in epidemiological studies, exploring the impact on postoperative populations, and estimating the association between air pollutant exposure and health effects. |
| format | Online |
| id | doab-20.500.12854ir-174874 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2026 |
| publishDateRange | 2026 |
| publishDateSort | 2026 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1748742026-04-16T17:07:09Z Toxicity and Human Health Assessment of Air Pollutants Wang, Ting Ku, Tingting Xu, Jia FB cells HaCaT cells 3D epidermal cells Environmental factors Cytotoxicity PM2.5 NO2 Geostatistical modeling approach Exposure estimates Misclassification Air pollution Vision disorder Meta-analysis Odds ratio Cadmium Tumor Colon cancer Reactive oxygen species Wnt Β-catenin pathway NAFLD UK Biobank Finngen Mendelian randomization Fine particulate matter Adverse birth outcomes Respiratory development Cardiovascular development Neurological development Mechanism Gasoline exhaust Diesel exhaust Lipid metabolism Liver function Oxidative stress Incense-burning smoke Early outdoor activity Joint effect Obesity Preschool child Public health Mortality burden Economic value OPCAB CAD LVEF Renal hyperfiltration Renin–angiotensin system Kallikrein–kinin system Tubular reabsorption Tubuloglomerular feedback N A thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::U Computing and Information Technology::UM Computer programming / software engineering::UMC Compilers and interpreters thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology::TQK Pollution control Air pollution has been shown to be responsible for the morbidity and mortality of a variety of major diseases. The World Health Organization (WHO) estimates that almost the whole global population breathes air that exceeds WHO guidelines and contains high levels of pollutants. To date, however, the key constituents of air pollution which impact health and the potential mechanisms remain largely unstudied. In addition, comprehensive assessments of evidence from in vitro and in vivo studies, high-quality cohort studies, and high-resolution model simulations of health impacts are still substantially sparse. Hence, assessing the health risks, identifying the toxic effects, and elucidating the underlying mechanisms are of great importance. This Reprint aims to understand the mechanisms of the health effects caused by air pollution and ensure accurate exposure assessments around ambient environments and inside human bodies, including a range of approaches—from epidemiological cohorts and toxicological studies—to elucidate the linkage between air pollutant exposure and the mechanisms related to health effects. The articles published in this Special Issue can be categorized into four main research directions: elucidating underlying toxicity mechanisms, identifying critical exposure windows and vulnerable populations in epidemiological studies, exploring the impact on postoperative populations, and estimating the association between air pollutant exposure and health effects. 2026-04-16T17:07:01Z 2026-04-16T17:07:01Z 2025 book ONIX_20260416T142754_9783725856770_29 9783725856770 9783725856787 https://directory.doabooks.org/handle/20.500.12854/174874 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/ https://mdpi.com/books/pdfview/book/11755 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-5678-7 10.3390/books978-3-7258-5678-7 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725856770 9783725856787 188 CH open access |
| spellingShingle | FB cells HaCaT cells 3D epidermal cells Environmental factors Cytotoxicity PM2.5 NO2 Geostatistical modeling approach Exposure estimates Misclassification Air pollution Vision disorder Meta-analysis Odds ratio Cadmium Tumor Colon cancer Reactive oxygen species Wnt Β-catenin pathway NAFLD UK Biobank Finngen Mendelian randomization Fine particulate matter Adverse birth outcomes Respiratory development Cardiovascular development Neurological development Mechanism Gasoline exhaust Diesel exhaust Lipid metabolism Liver function Oxidative stress Incense-burning smoke Early outdoor activity Joint effect Obesity Preschool child Public health Mortality burden Economic value OPCAB CAD LVEF Renal hyperfiltration Renin–angiotensin system Kallikrein–kinin system Tubular reabsorption Tubuloglomerular feedback N A thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::U Computing and Information Technology::UM Computer programming / software engineering::UMC Compilers and interpreters thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology::TQK Pollution control Toxicity and Human Health Assessment of Air Pollutants |
| title | Toxicity and Human Health Assessment of Air Pollutants |
| title_full | Toxicity and Human Health Assessment of Air Pollutants |
| title_fullStr | Toxicity and Human Health Assessment of Air Pollutants |
| title_full_unstemmed | Toxicity and Human Health Assessment of Air Pollutants |
| title_short | Toxicity and Human Health Assessment of Air Pollutants |
| title_sort | toxicity and human health assessment of air pollutants |
| topic | FB cells HaCaT cells 3D epidermal cells Environmental factors Cytotoxicity PM2.5 NO2 Geostatistical modeling approach Exposure estimates Misclassification Air pollution Vision disorder Meta-analysis Odds ratio Cadmium Tumor Colon cancer Reactive oxygen species Wnt Β-catenin pathway NAFLD UK Biobank Finngen Mendelian randomization Fine particulate matter Adverse birth outcomes Respiratory development Cardiovascular development Neurological development Mechanism Gasoline exhaust Diesel exhaust Lipid metabolism Liver function Oxidative stress Incense-burning smoke Early outdoor activity Joint effect Obesity Preschool child Public health Mortality burden Economic value OPCAB CAD LVEF Renal hyperfiltration Renin–angiotensin system Kallikrein–kinin system Tubular reabsorption Tubuloglomerular feedback N A thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::U Computing and Information Technology::UM Computer programming / software engineering::UMC Compilers and interpreters thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology::TQK Pollution control |
| topic_facet | FB cells HaCaT cells 3D epidermal cells Environmental factors Cytotoxicity PM2.5 NO2 Geostatistical modeling approach Exposure estimates Misclassification Air pollution Vision disorder Meta-analysis Odds ratio Cadmium Tumor Colon cancer Reactive oxygen species Wnt Β-catenin pathway NAFLD UK Biobank Finngen Mendelian randomization Fine particulate matter Adverse birth outcomes Respiratory development Cardiovascular development Neurological development Mechanism Gasoline exhaust Diesel exhaust Lipid metabolism Liver function Oxidative stress Incense-burning smoke Early outdoor activity Joint effect Obesity Preschool child Public health Mortality burden Economic value OPCAB CAD LVEF Renal hyperfiltration Renin–angiotensin system Kallikrein–kinin system Tubular reabsorption Tubuloglomerular feedback N A thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::U Computing and Information Technology::UM Computer programming / software engineering::UMC Compilers and interpreters thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology::TQK Pollution control |
| url | ONIX_20260416T142754_9783725856770_29 |