Genetic Engineering in Microbial Biotechnology

This Reprint brings together contributions from the Special Issue on Genetic Engineering in Microbial Biotechnology, originally published in the International Journal of Molecular Sciences. Under the guest editorship of Dr. Fernando Santos-Beneit, the collection addresses the key intersection of gen...

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Izdano: MDPI - Multidisciplinary Digital Publishing Institute 2026
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collection Directory of Open Access Books
description This Reprint brings together contributions from the Special Issue on Genetic Engineering in Microbial Biotechnology, originally published in the International Journal of Molecular Sciences. Under the guest editorship of Dr. Fernando Santos-Beneit, the collection addresses the key intersection of gene-based technologies and microbial systems, exploring how microorganisms may be harnessed for sustainable innovation. Featuring both original research and authoritative reviews, the Reprint encompasses topics such as white, red, yellow, green, and other branches of biotechnology; bioinformatic analyses; metabolic engineering; microbial genetic circuits; degradation of synthetic polymers; biosynthesis of bioproducts; enzyme engineering; antimicrobial resistance; and novel secondary metabolites. Collectively, these studies seek to confront pressing challenges of modern society—such as the climate crisis, environmental pollution, and health threats—by leveraging the smallest forms of life. Each paper in the Reprint exemplifies rigorous experimental design, computational insight, and strategic engineering aimed at translational or applied outcomes. Whether enhancing bioproduct yield, developing biodegradable polymers, or elucidating novel genetic pathways, the contributions illustrate the compelling promise of genetically engineered microorganisms in illuminating new biotechnological possibilities. The Reprint offers both researchers and practitioners a curated resource of cutting-edge developments and future directions in microbial genetic engineering, providing a foundation for further progress toward a more sustainable and innovative bioeconomy.
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language eng
publishDate 2026
publishDateRange 2026
publishDateSort 2026
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-1748942026-04-16T17:12:38Z Genetic Engineering in Microbial Biotechnology Santos-Beneit, Fernando Flavonoid Biosynthesis O-methyltransferase Regiospecificity Metabolic engineering Inflammatory bowel disease Gut microbiota Anti-inflammatory C22 steroids 9 22-dihydroxy-23 24-bisnorchol-4-enehp-3-one(9-OHBA) Mycobacterium fortuitum Phytosterol Hsd4A FadA5 Synthetic polymers Plastics Biodegradation Genetic engineering PET PETase Cutinase Esterase 2 3-butanediol Bacillus licheniformis SacB Exopolysaccharides Inulin Saccharopolyspora spinosa ARTP NTG mutagenesis Spinosad Biotechnology Puromycin Cystocin Aminonucleoside antibiotics Resistance Genome mining Antimicrobial activity Cytotoxicity Restriction–modification systems Type II restriction endonuclease PsaI Isoschizomer HindIII thema EDItEUR::P Mathematics and Science::PS Biology, life sciences This Reprint brings together contributions from the Special Issue on Genetic Engineering in Microbial Biotechnology, originally published in the International Journal of Molecular Sciences. Under the guest editorship of Dr. Fernando Santos-Beneit, the collection addresses the key intersection of gene-based technologies and microbial systems, exploring how microorganisms may be harnessed for sustainable innovation. Featuring both original research and authoritative reviews, the Reprint encompasses topics such as white, red, yellow, green, and other branches of biotechnology; bioinformatic analyses; metabolic engineering; microbial genetic circuits; degradation of synthetic polymers; biosynthesis of bioproducts; enzyme engineering; antimicrobial resistance; and novel secondary metabolites. Collectively, these studies seek to confront pressing challenges of modern society—such as the climate crisis, environmental pollution, and health threats—by leveraging the smallest forms of life. Each paper in the Reprint exemplifies rigorous experimental design, computational insight, and strategic engineering aimed at translational or applied outcomes. Whether enhancing bioproduct yield, developing biodegradable polymers, or elucidating novel genetic pathways, the contributions illustrate the compelling promise of genetically engineered microorganisms in illuminating new biotechnological possibilities. The Reprint offers both researchers and practitioners a curated resource of cutting-edge developments and future directions in microbial genetic engineering, providing a foundation for further progress toward a more sustainable and innovative bioeconomy. 2026-04-16T17:12:30Z 2026-04-16T17:12:30Z 2025 book ONIX_20260416T142754_9783725853458_49 9783725853458 9783725853465 https://directory.doabooks.org/handle/20.500.12854/174894 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/ https://mdpi.com/books/pdfview/book/11775 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-5346-5 10.3390/books978-3-7258-5346-5 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725853458 9783725853465 146 CH open access
spellingShingle Flavonoid
Biosynthesis
O-methyltransferase
Regiospecificity
Metabolic engineering
Inflammatory bowel disease
Gut microbiota
Anti-inflammatory
C22 steroids
9
22-dihydroxy-23
24-bisnorchol-4-enehp-3-one(9-OHBA)
Mycobacterium fortuitum
Phytosterol
Hsd4A
FadA5
Synthetic polymers
Plastics
Biodegradation
Genetic engineering
PET
PETase
Cutinase
Esterase
2
3-butanediol
Bacillus licheniformis
SacB
Exopolysaccharides
Inulin
Saccharopolyspora spinosa
ARTP
NTG mutagenesis
Spinosad
Biotechnology
Puromycin
Cystocin
Aminonucleoside antibiotics
Resistance
Genome mining
Antimicrobial activity
Cytotoxicity
Restriction–modification systems
Type II restriction endonuclease PsaI
Isoschizomer HindIII
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Genetic Engineering in Microbial Biotechnology
title Genetic Engineering in Microbial Biotechnology
title_full Genetic Engineering in Microbial Biotechnology
title_fullStr Genetic Engineering in Microbial Biotechnology
title_full_unstemmed Genetic Engineering in Microbial Biotechnology
title_short Genetic Engineering in Microbial Biotechnology
title_sort genetic engineering in microbial biotechnology
topic Flavonoid
Biosynthesis
O-methyltransferase
Regiospecificity
Metabolic engineering
Inflammatory bowel disease
Gut microbiota
Anti-inflammatory
C22 steroids
9
22-dihydroxy-23
24-bisnorchol-4-enehp-3-one(9-OHBA)
Mycobacterium fortuitum
Phytosterol
Hsd4A
FadA5
Synthetic polymers
Plastics
Biodegradation
Genetic engineering
PET
PETase
Cutinase
Esterase
2
3-butanediol
Bacillus licheniformis
SacB
Exopolysaccharides
Inulin
Saccharopolyspora spinosa
ARTP
NTG mutagenesis
Spinosad
Biotechnology
Puromycin
Cystocin
Aminonucleoside antibiotics
Resistance
Genome mining
Antimicrobial activity
Cytotoxicity
Restriction–modification systems
Type II restriction endonuclease PsaI
Isoschizomer HindIII
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet Flavonoid
Biosynthesis
O-methyltransferase
Regiospecificity
Metabolic engineering
Inflammatory bowel disease
Gut microbiota
Anti-inflammatory
C22 steroids
9
22-dihydroxy-23
24-bisnorchol-4-enehp-3-one(9-OHBA)
Mycobacterium fortuitum
Phytosterol
Hsd4A
FadA5
Synthetic polymers
Plastics
Biodegradation
Genetic engineering
PET
PETase
Cutinase
Esterase
2
3-butanediol
Bacillus licheniformis
SacB
Exopolysaccharides
Inulin
Saccharopolyspora spinosa
ARTP
NTG mutagenesis
Spinosad
Biotechnology
Puromycin
Cystocin
Aminonucleoside antibiotics
Resistance
Genome mining
Antimicrobial activity
Cytotoxicity
Restriction–modification systems
Type II restriction endonuclease PsaI
Isoschizomer HindIII
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url ONIX_20260416T142754_9783725853458_49