Circulating Non-coding RNAs as Diagnostic and Prognostic Markers of Human Diseases
This Reprint of the IJMS Special Issue “Circulating Non-Coding RNAs as Diagnostic and Prognostic Markers of Human Diseases” presents eight original research papers and five reviews that advance our diagnostic, prognostic, and mechanistic understanding of circulating non-coding RNAs (c-ncRNAs). The c...
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| Format: | Online |
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| Jezik: | engleski |
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MDPI - Multidisciplinary Digital Publishing Institute
2026
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| Online pristup: | ONIX_20260416T142754_9783725856671_29 |
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| collection | Directory of Open Access Books |
| description | This Reprint of the IJMS Special Issue “Circulating Non-Coding RNAs as Diagnostic and Prognostic Markers of Human Diseases” presents eight original research papers and five reviews that advance our diagnostic, prognostic, and mechanistic understanding of circulating non-coding RNAs (c-ncRNAs). The collection emphasizes the remarkable stability of c-ncRNAs in biofluids such as blood and urine, their tissue- and disease-specific expression profiles, and their growing promise in non-invasive liquid biopsy for precision medicine, spanning early detection, risk assessment, and therapeutic monitoring. Featured studies explore early lung cancer prediction in COPD via miR-206 and miR-1246; risk stratification in atrial fibrillation using miR-411-5p; the differentiation of coronary artery aneurysmal disease through miR-451a and miR-328-3p; the staging of mycosis fungoides by plasma miR-146a and miR-155; and asthma phenotyping associated with hsa-miR-26a-1-3p and hsa-miR-376a-3p. Additional research investigates NAFLD diagnostics using serum miRNA ratios and provides mechanistic insight into muscle development via circTTN. The reviews synthesize advances on c-miRNAs in osteoarthritis, miRNA and exosomal miRNA dysregulation in cholesteatoma, therapeutic biomarkers in asthma, and post–SARS-CoV-2 cardiovascular alterations, highlighting broad clinical relevance across oncologic, cardiovascular, metabolic, and inflammatory disorders. Collectively, these contributions underscore methodological progress toward standardization and position c-ncRNAs at the forefront of minimally invasive diagnostics and personalized therapy. |
| format | Online |
| id | doab-20.500.12854ir-174924 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2026 |
| publishDateRange | 2026 |
| publishDateSort | 2026 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1749242026-04-16T17:23:14Z Circulating Non-coding RNAs as Diagnostic and Prognostic Markers of Human Diseases Felekkis, Kyriacos N. Papaneophytou, Christos Non-coding RNAs MiRNAs Biomarkers Gene expression regulation Diagnosis Prognosis Therapy Liquid biopsy thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences This Reprint of the IJMS Special Issue “Circulating Non-Coding RNAs as Diagnostic and Prognostic Markers of Human Diseases” presents eight original research papers and five reviews that advance our diagnostic, prognostic, and mechanistic understanding of circulating non-coding RNAs (c-ncRNAs). The collection emphasizes the remarkable stability of c-ncRNAs in biofluids such as blood and urine, their tissue- and disease-specific expression profiles, and their growing promise in non-invasive liquid biopsy for precision medicine, spanning early detection, risk assessment, and therapeutic monitoring. Featured studies explore early lung cancer prediction in COPD via miR-206 and miR-1246; risk stratification in atrial fibrillation using miR-411-5p; the differentiation of coronary artery aneurysmal disease through miR-451a and miR-328-3p; the staging of mycosis fungoides by plasma miR-146a and miR-155; and asthma phenotyping associated with hsa-miR-26a-1-3p and hsa-miR-376a-3p. Additional research investigates NAFLD diagnostics using serum miRNA ratios and provides mechanistic insight into muscle development via circTTN. The reviews synthesize advances on c-miRNAs in osteoarthritis, miRNA and exosomal miRNA dysregulation in cholesteatoma, therapeutic biomarkers in asthma, and post–SARS-CoV-2 cardiovascular alterations, highlighting broad clinical relevance across oncologic, cardiovascular, metabolic, and inflammatory disorders. Collectively, these contributions underscore methodological progress toward standardization and position c-ncRNAs at the forefront of minimally invasive diagnostics and personalized therapy. 2026-04-16T17:23:06Z 2026-04-16T17:23:06Z 2025 book ONIX_20260416T142754_9783725856671_29 9783725856671 9783725856688 https://directory.doabooks.org/handle/20.500.12854/174924 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/ https://mdpi.com/books/pdfview/book/11823 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-5668-8 10.3390/books978-3-7258-5668-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725856671 9783725856688 236 CH open access |
| spellingShingle | Non-coding RNAs MiRNAs Biomarkers Gene expression regulation Diagnosis Prognosis Therapy Liquid biopsy thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Circulating Non-coding RNAs as Diagnostic and Prognostic Markers of Human Diseases |
| title | Circulating Non-coding RNAs as Diagnostic and Prognostic Markers of Human Diseases |
| title_full | Circulating Non-coding RNAs as Diagnostic and Prognostic Markers of Human Diseases |
| title_fullStr | Circulating Non-coding RNAs as Diagnostic and Prognostic Markers of Human Diseases |
| title_full_unstemmed | Circulating Non-coding RNAs as Diagnostic and Prognostic Markers of Human Diseases |
| title_short | Circulating Non-coding RNAs as Diagnostic and Prognostic Markers of Human Diseases |
| title_sort | circulating non coding rnas as diagnostic and prognostic markers of human diseases |
| topic | Non-coding RNAs MiRNAs Biomarkers Gene expression regulation Diagnosis Prognosis Therapy Liquid biopsy thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | Non-coding RNAs MiRNAs Biomarkers Gene expression regulation Diagnosis Prognosis Therapy Liquid biopsy thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20260416T142754_9783725856671_29 |