Inflammatory Bowel Disease

Inflammatory bowel diseases (IBDs) are chronic inflammatory intestinal conditions of unknown cause. The main types are Crohn’s disease (CD) and ulcerative colitis (UC). Diagnosis typically involves clinical symptoms, laboratory tests, and endoscopic features, along with radiological exams like magne...

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Format: Online
Language:English
Published: MDPI - Multidisciplinary Digital Publishing Institute 2026
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Online Access:ONIX_20260416T142754_9783725848195_46
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collection Directory of Open Access Books
description Inflammatory bowel diseases (IBDs) are chronic inflammatory intestinal conditions of unknown cause. The main types are Crohn’s disease (CD) and ulcerative colitis (UC). Diagnosis typically involves clinical symptoms, laboratory tests, and endoscopic features, along with radiological exams like magnetic resonance imaging (MRI) and computed tomography (CT) enterography, which are crucial for diagnosing and staging CD. CT is effective for evaluating disease activity and complications, such as fistulas and strictures, particularly in acute cases. However, MRI has increasingly replaced CT due to its comparable sensitivity, specificity, and accuracy in diagnosing CD and assessing disease activity without radiation exposure. IBDs require ongoing treatment to manage inflammation and prevent progression. The therapeutic options have expanded significantly with advanced therapies, including biological treatments and small molecules. Nevertheless, surgery remains necessary for complications like abscesses, fistulas, perforation, and strictures, which occur in 48%-52% of CD patients within five years, or for diseases that do not respond to medication. Regular monitoring and therapy adjustments are essential to assess treatment response and identify those needing surgery. This reprint provides information on clinical, diagnostic, and treatment methods for IBDs.
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publisher MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-1749412026-04-16T17:27:34Z Inflammatory Bowel Disease Minordi, Laura Maria Pugliese, Daniela Gastroenterology Inflammatory bowel disease Crohn&rsquo S disease Ulcerative colitis Endoscopy Surgery Advanced therapies thema EDItEUR::M Medicine and Nursing Inflammatory bowel diseases (IBDs) are chronic inflammatory intestinal conditions of unknown cause. The main types are Crohn’s disease (CD) and ulcerative colitis (UC). Diagnosis typically involves clinical symptoms, laboratory tests, and endoscopic features, along with radiological exams like magnetic resonance imaging (MRI) and computed tomography (CT) enterography, which are crucial for diagnosing and staging CD. CT is effective for evaluating disease activity and complications, such as fistulas and strictures, particularly in acute cases. However, MRI has increasingly replaced CT due to its comparable sensitivity, specificity, and accuracy in diagnosing CD and assessing disease activity without radiation exposure. IBDs require ongoing treatment to manage inflammation and prevent progression. The therapeutic options have expanded significantly with advanced therapies, including biological treatments and small molecules. Nevertheless, surgery remains necessary for complications like abscesses, fistulas, perforation, and strictures, which occur in 48%-52% of CD patients within five years, or for diseases that do not respond to medication. Regular monitoring and therapy adjustments are essential to assess treatment response and identify those needing surgery. This reprint provides information on clinical, diagnostic, and treatment methods for IBDs. 2026-04-16T17:27:29Z 2026-04-16T17:27:29Z 2025 book ONIX_20260416T142754_9783725848195_46 9783725848195 9783725848201 https://directory.doabooks.org/handle/20.500.12854/174941 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/ https://mdpi.com/books/pdfview/book/11840 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-4820-1 10.3390/books978-3-7258-4820-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725848195 9783725848201 174 CH open access
spellingShingle Gastroenterology
Inflammatory bowel disease
Crohn&rsquo
S disease
Ulcerative colitis
Endoscopy
Surgery
Advanced therapies
thema EDItEUR::M Medicine and Nursing
Inflammatory Bowel Disease
title Inflammatory Bowel Disease
title_full Inflammatory Bowel Disease
title_fullStr Inflammatory Bowel Disease
title_full_unstemmed Inflammatory Bowel Disease
title_short Inflammatory Bowel Disease
title_sort inflammatory bowel disease
topic Gastroenterology
Inflammatory bowel disease
Crohn&rsquo
S disease
Ulcerative colitis
Endoscopy
Surgery
Advanced therapies
thema EDItEUR::M Medicine and Nursing
topic_facet Gastroenterology
Inflammatory bowel disease
Crohn&rsquo
S disease
Ulcerative colitis
Endoscopy
Surgery
Advanced therapies
thema EDItEUR::M Medicine and Nursing
url ONIX_20260416T142754_9783725848195_46