Natural Products and Their Modifications as Agents Used in the Fight against Pathogens
The increasing resistance of bacterial strains to commercially available antibiotics remains one of the most pressing challenges in modern medicine. Consequently, the identification and characterization of novel bioactive compounds of natural origin have become essential in combating this global iss...
Na minha lista:
| Formato: | Online |
|---|---|
| Idioma: | inglês |
| Publicado em: |
MDPI - Multidisciplinary Digital Publishing Institute
2026
|
| Assuntos: | |
| Acesso em linha: | ONIX_20260416T142754_9783725860838_29 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|
| _version_ | 1869524605797924864 |
|---|---|
| collection | Directory of Open Access Books |
| description | The increasing resistance of bacterial strains to commercially available antibiotics remains one of the most pressing challenges in modern medicine. Consequently, the identification and characterization of novel bioactive compounds of natural origin have become essential in combating this global issue. Equally crucial is the preservation of the intestinal microbiota, which plays a pivotal role in maintaining systemic homeostasis and overall health. Natural extracts exhibit diverse biological activities and frequently exert protective effects on the gut microbiota. Therefore, the rational design and selection of chemical modifications that enhance antimicrobial activity while simultaneously supporting immune functions, and demonstrating anti-inflammatory and anti-proliferative properties, are of particular scientific interest. This Reprint brings together research and review articles focusing on these key aspects. It presents studies comparing the biological activity of pathogenic bacterial strains and/or intestinal microbiota in the presence of natural compounds and their chemically modified derivatives. Manuscripts included in this collection also explore the bioactivity of crude plant extracts, isolated compounds, and dominant phytochemical combinations naturally occurring in plants. Moreover, this Reprint highlights the potential of extracts and their major constituents’ processes. These approaches represent a promising direction in the ongoing development of novel therapeutic strategies against infections caused by multidrug-resistant microorganisms. |
| format | Online |
| id | doab-20.500.12854ir-175074 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2026 |
| publishDateRange | 2026 |
| publishDateSort | 2026 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1750742026-04-16T18:47:51Z Natural Products and Their Modifications as Agents Used in the Fight against Pathogens Duda-Madej, Anna Globularia alypum L. HPLC-DAD Antioxidant activity Anti-arthritic activity Antiproliferative effect Antibacterial and antibiofilm activities Catharanthus roseus NMR Indole alkaloids Secondary metabolites Antibacterial Food preservation Peony roots Chemical characterization Fourier-transform infrared spectroscopy Antibacterial activity Enzyme-inhibitory activity In vitro gastrointestinal digestion Camphor Antifungal activity Drug resistance Skin infections Wound healing Monoterpenoids Natural compounds Honeydew Antibacterial effect Hydrogen peroxide Polyphenolic compounds Anethum graveolens GC MS HPLC UV-ESI-MS Polyphenols Flavonoids Antioxidants Antimicrobials Rosmarinus officinalis Essential oil Escherichia coli Klebsiella pneumoniae MRSA Streptococcus mutans Bacillus subtilis Pseudomonas aeruginosa Salmonella Typhi Antimicrobial activity Antiviral activity Herpesvirus Hyperforin Lipid nanoparticles Nanostructured lipid carriers Phloroglucinols St. John’s wort Heracleum Antibiofilm Antimicrobial Antioxidant Anti-quorum sensing Essential oils Phytochemical Berberine Β-lactamase inhibitors Efflux pump inhibitors FtsZ protein Isoquinoline alkaloid Multidrug resistance Quorum sensing inhibitors thema EDItEUR::M Medicine and Nursing The increasing resistance of bacterial strains to commercially available antibiotics remains one of the most pressing challenges in modern medicine. Consequently, the identification and characterization of novel bioactive compounds of natural origin have become essential in combating this global issue. Equally crucial is the preservation of the intestinal microbiota, which plays a pivotal role in maintaining systemic homeostasis and overall health. Natural extracts exhibit diverse biological activities and frequently exert protective effects on the gut microbiota. Therefore, the rational design and selection of chemical modifications that enhance antimicrobial activity while simultaneously supporting immune functions, and demonstrating anti-inflammatory and anti-proliferative properties, are of particular scientific interest. This Reprint brings together research and review articles focusing on these key aspects. It presents studies comparing the biological activity of pathogenic bacterial strains and/or intestinal microbiota in the presence of natural compounds and their chemically modified derivatives. Manuscripts included in this collection also explore the bioactivity of crude plant extracts, isolated compounds, and dominant phytochemical combinations naturally occurring in plants. Moreover, this Reprint highlights the potential of extracts and their major constituents’ processes. These approaches represent a promising direction in the ongoing development of novel therapeutic strategies against infections caused by multidrug-resistant microorganisms. 2026-04-16T18:47:45Z 2026-04-16T18:47:45Z 2025 book ONIX_20260416T142754_9783725860838_29 9783725860838 9783725860845 https://directory.doabooks.org/handle/20.500.12854/175074 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/ https://mdpi.com/books/pdfview/book/11977 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-6084-5 10.3390/books978-3-7258-6084-5 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725860838 9783725860845 238 CH open access |
| spellingShingle | Globularia alypum L. HPLC-DAD Antioxidant activity Anti-arthritic activity Antiproliferative effect Antibacterial and antibiofilm activities Catharanthus roseus NMR Indole alkaloids Secondary metabolites Antibacterial Food preservation Peony roots Chemical characterization Fourier-transform infrared spectroscopy Antibacterial activity Enzyme-inhibitory activity In vitro gastrointestinal digestion Camphor Antifungal activity Drug resistance Skin infections Wound healing Monoterpenoids Natural compounds Honeydew Antibacterial effect Hydrogen peroxide Polyphenolic compounds Anethum graveolens GC MS HPLC UV-ESI-MS Polyphenols Flavonoids Antioxidants Antimicrobials Rosmarinus officinalis Essential oil Escherichia coli Klebsiella pneumoniae MRSA Streptococcus mutans Bacillus subtilis Pseudomonas aeruginosa Salmonella Typhi Antimicrobial activity Antiviral activity Herpesvirus Hyperforin Lipid nanoparticles Nanostructured lipid carriers Phloroglucinols St. John’s wort Heracleum Antibiofilm Antimicrobial Antioxidant Anti-quorum sensing Essential oils Phytochemical Berberine Β-lactamase inhibitors Efflux pump inhibitors FtsZ protein Isoquinoline alkaloid Multidrug resistance Quorum sensing inhibitors thema EDItEUR::M Medicine and Nursing Natural Products and Their Modifications as Agents Used in the Fight against Pathogens |
| title | Natural Products and Their Modifications as Agents Used in the Fight against Pathogens |
| title_full | Natural Products and Their Modifications as Agents Used in the Fight against Pathogens |
| title_fullStr | Natural Products and Their Modifications as Agents Used in the Fight against Pathogens |
| title_full_unstemmed | Natural Products and Their Modifications as Agents Used in the Fight against Pathogens |
| title_short | Natural Products and Their Modifications as Agents Used in the Fight against Pathogens |
| title_sort | natural products and their modifications as agents used in the fight against pathogens |
| topic | Globularia alypum L. HPLC-DAD Antioxidant activity Anti-arthritic activity Antiproliferative effect Antibacterial and antibiofilm activities Catharanthus roseus NMR Indole alkaloids Secondary metabolites Antibacterial Food preservation Peony roots Chemical characterization Fourier-transform infrared spectroscopy Antibacterial activity Enzyme-inhibitory activity In vitro gastrointestinal digestion Camphor Antifungal activity Drug resistance Skin infections Wound healing Monoterpenoids Natural compounds Honeydew Antibacterial effect Hydrogen peroxide Polyphenolic compounds Anethum graveolens GC MS HPLC UV-ESI-MS Polyphenols Flavonoids Antioxidants Antimicrobials Rosmarinus officinalis Essential oil Escherichia coli Klebsiella pneumoniae MRSA Streptococcus mutans Bacillus subtilis Pseudomonas aeruginosa Salmonella Typhi Antimicrobial activity Antiviral activity Herpesvirus Hyperforin Lipid nanoparticles Nanostructured lipid carriers Phloroglucinols St. John’s wort Heracleum Antibiofilm Antimicrobial Antioxidant Anti-quorum sensing Essential oils Phytochemical Berberine Β-lactamase inhibitors Efflux pump inhibitors FtsZ protein Isoquinoline alkaloid Multidrug resistance Quorum sensing inhibitors thema EDItEUR::M Medicine and Nursing |
| topic_facet | Globularia alypum L. HPLC-DAD Antioxidant activity Anti-arthritic activity Antiproliferative effect Antibacterial and antibiofilm activities Catharanthus roseus NMR Indole alkaloids Secondary metabolites Antibacterial Food preservation Peony roots Chemical characterization Fourier-transform infrared spectroscopy Antibacterial activity Enzyme-inhibitory activity In vitro gastrointestinal digestion Camphor Antifungal activity Drug resistance Skin infections Wound healing Monoterpenoids Natural compounds Honeydew Antibacterial effect Hydrogen peroxide Polyphenolic compounds Anethum graveolens GC MS HPLC UV-ESI-MS Polyphenols Flavonoids Antioxidants Antimicrobials Rosmarinus officinalis Essential oil Escherichia coli Klebsiella pneumoniae MRSA Streptococcus mutans Bacillus subtilis Pseudomonas aeruginosa Salmonella Typhi Antimicrobial activity Antiviral activity Herpesvirus Hyperforin Lipid nanoparticles Nanostructured lipid carriers Phloroglucinols St. John’s wort Heracleum Antibiofilm Antimicrobial Antioxidant Anti-quorum sensing Essential oils Phytochemical Berberine Β-lactamase inhibitors Efflux pump inhibitors FtsZ protein Isoquinoline alkaloid Multidrug resistance Quorum sensing inhibitors thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20260416T142754_9783725860838_29 |