Antimicrobial Resistance and Antimicrobial Therapy of Clinically Relevant Bacteria

Antimicrobial resistance is a public health problem of major importance, and the World Health Organization (WHO) has warned that the current antibiotic armamentarium is not sufficient to face future challenges. The antibiotic pipeline is not providing new compounds at a sufficient speed for various...

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collection Directory of Open Access Books
description Antimicrobial resistance is a public health problem of major importance, and the World Health Organization (WHO) has warned that the current antibiotic armamentarium is not sufficient to face future challenges. The antibiotic pipeline is not providing new compounds at a sufficient speed for various reasons, and thus, few novel drugs have reached clinical practice lately; old, formerly abandoned antimicrobials are increasingly used as last-resort treatment options. At this pace, untreatable infections could emerge on a large scale, and the world may experience, in some cases, dramatic situations of the pre-antibiotic era. Already, clinicians in endemic areas routinely encounter patients with infections that do not respond to available treatments, and laboratories often report multidrug-resistant (MDR) or even pan-drug-resistant (PDR) bacteria. In this context, continuous monitoring of the resistance mechanisms’ epidemiology, as well as knowledge regarding treatment options for clinically relevant bacteria, are of great interest to health-care professionals. This Reprint includes articles that present new data on antimicrobial resistance and epidemiology of MDR bacterial infections of key clinical importance, as well as suitable therapeutic options for their treatment. Hopefully, these contributions will both practically benefit the readership and stimulate further research in the field.
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spelling doab-20.500.12854ir-1751172026-04-16T19:02:09Z Antimicrobial Resistance and Antimicrobial Therapy of Clinically Relevant Bacteria Meletis, Georgios Skoura, Lemonia Protonotariou, Efthymia Antimicrobial resistance mechanisms Antimicrobial resistance detection Antimicrobial resistance epidemiology Antimicrobial treatment New antibiotics MDR Klebsiella pneumoniae Acinetobacter baumannii Pseudomonas aeruginosa MRSA thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Antimicrobial resistance is a public health problem of major importance, and the World Health Organization (WHO) has warned that the current antibiotic armamentarium is not sufficient to face future challenges. The antibiotic pipeline is not providing new compounds at a sufficient speed for various reasons, and thus, few novel drugs have reached clinical practice lately; old, formerly abandoned antimicrobials are increasingly used as last-resort treatment options. At this pace, untreatable infections could emerge on a large scale, and the world may experience, in some cases, dramatic situations of the pre-antibiotic era. Already, clinicians in endemic areas routinely encounter patients with infections that do not respond to available treatments, and laboratories often report multidrug-resistant (MDR) or even pan-drug-resistant (PDR) bacteria. In this context, continuous monitoring of the resistance mechanisms’ epidemiology, as well as knowledge regarding treatment options for clinically relevant bacteria, are of great interest to health-care professionals. This Reprint includes articles that present new data on antimicrobial resistance and epidemiology of MDR bacterial infections of key clinical importance, as well as suitable therapeutic options for their treatment. Hopefully, these contributions will both practically benefit the readership and stimulate further research in the field. 2026-04-16T19:02:06Z 2026-04-16T19:02:06Z 2025 book ONIX_20260416T142754_9783725860777_22 9783725860777 9783725860784 https://directory.doabooks.org/handle/20.500.12854/175117 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/ https://mdpi.com/books/pdfview/book/12022 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-6078-4 10.3390/books978-3-7258-6078-4 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725860777 9783725860784 114 CH open access
spellingShingle Antimicrobial resistance mechanisms
Antimicrobial resistance detection
Antimicrobial resistance epidemiology
Antimicrobial treatment
New antibiotics
MDR
Klebsiella pneumoniae
Acinetobacter baumannii
Pseudomonas aeruginosa
MRSA
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Antimicrobial Resistance and Antimicrobial Therapy of Clinically Relevant Bacteria
title Antimicrobial Resistance and Antimicrobial Therapy of Clinically Relevant Bacteria
title_full Antimicrobial Resistance and Antimicrobial Therapy of Clinically Relevant Bacteria
title_fullStr Antimicrobial Resistance and Antimicrobial Therapy of Clinically Relevant Bacteria
title_full_unstemmed Antimicrobial Resistance and Antimicrobial Therapy of Clinically Relevant Bacteria
title_short Antimicrobial Resistance and Antimicrobial Therapy of Clinically Relevant Bacteria
title_sort antimicrobial resistance and antimicrobial therapy of clinically relevant bacteria
topic Antimicrobial resistance mechanisms
Antimicrobial resistance detection
Antimicrobial resistance epidemiology
Antimicrobial treatment
New antibiotics
MDR
Klebsiella pneumoniae
Acinetobacter baumannii
Pseudomonas aeruginosa
MRSA
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet Antimicrobial resistance mechanisms
Antimicrobial resistance detection
Antimicrobial resistance epidemiology
Antimicrobial treatment
New antibiotics
MDR
Klebsiella pneumoniae
Acinetobacter baumannii
Pseudomonas aeruginosa
MRSA
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url ONIX_20260416T142754_9783725860777_22