Biomolecular Approaches and Drugs for Neurodegeneration

This reprint presents a collection of recent contributions addressing the urgent challenges posed by neurodegenerative diseases. In more detail, it explores therapeutic convergence through natural products, drug repurposing, and biomolecular targets, while also examining specific topics like the sel...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Formato: Online
Idioma:inglês
Publicado em: MDPI - Multidisciplinary Digital Publishing Institute 2026
Assuntos:
Acesso em linha:ONIX_20260416T142754_9783725861934_20
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
_version_ 1869530983245545472
collection Directory of Open Access Books
description This reprint presents a collection of recent contributions addressing the urgent challenges posed by neurodegenerative diseases. In more detail, it explores therapeutic convergence through natural products, drug repurposing, and biomolecular targets, while also examining specific topics like the selective vulnerability of neuronal populations in Alzheimer’s disease (AD), cholesterol metabolism in microglia, and innovative approaches to prion inhibition. We also report on studies highlighting mitochondria as key modulators of neurodegeneration. The work also presents nutraceutical strategies in Parkinson’s disease (PD) models and investigates anti-inflammatory compounds able to regulate microglial activity. The reprint further expands on the neuroprotective potential of plant-derived molecules, adrenergic receptor signaling in AD, immune system involvement in multiple sclerosis, and therapeutic strategies for spinocerebellar ataxia. Collectively, the different topics discussed in this work emphasize the multifaceted nature of neurodegeneration research, demonstrating how molecular insights, pharmacological innovation, and translational approaches converge to pave the way for future neurotherapies.
format Online
id doab-20.500.12854ir-175165
institution Directory of Open Access Books
language eng
publishDate 2026
publishDateRange 2026
publishDateSort 2026
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
record_format ojs
spelling doab-20.500.12854ir-1751652026-04-16T19:18:39Z Biomolecular Approaches and Drugs for Neurodegeneration Roviello, Giovanni N. Vicidomini, Caterina Neurodegeneration Drug discovery Neurodisease Alzheimer disease Parkinson&rsquo S disease thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences This reprint presents a collection of recent contributions addressing the urgent challenges posed by neurodegenerative diseases. In more detail, it explores therapeutic convergence through natural products, drug repurposing, and biomolecular targets, while also examining specific topics like the selective vulnerability of neuronal populations in Alzheimer’s disease (AD), cholesterol metabolism in microglia, and innovative approaches to prion inhibition. We also report on studies highlighting mitochondria as key modulators of neurodegeneration. The work also presents nutraceutical strategies in Parkinson’s disease (PD) models and investigates anti-inflammatory compounds able to regulate microglial activity. The reprint further expands on the neuroprotective potential of plant-derived molecules, adrenergic receptor signaling in AD, immune system involvement in multiple sclerosis, and therapeutic strategies for spinocerebellar ataxia. Collectively, the different topics discussed in this work emphasize the multifaceted nature of neurodegeneration research, demonstrating how molecular insights, pharmacological innovation, and translational approaches converge to pave the way for future neurotherapies. 2026-04-16T19:18:33Z 2026-04-16T19:18:33Z 2026 book ONIX_20260416T142754_9783725861934_20 9783725861934 9783725861941 https://directory.doabooks.org/handle/20.500.12854/175165 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/ https://mdpi.com/books/pdfview/book/12077 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-6194-1 10.3390/books978-3-7258-6194-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725861934 9783725861941 222 CH open access
spellingShingle Neurodegeneration
Drug discovery
Neurodisease
Alzheimer disease
Parkinson&rsquo
S disease
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Biomolecular Approaches and Drugs for Neurodegeneration
title Biomolecular Approaches and Drugs for Neurodegeneration
title_full Biomolecular Approaches and Drugs for Neurodegeneration
title_fullStr Biomolecular Approaches and Drugs for Neurodegeneration
title_full_unstemmed Biomolecular Approaches and Drugs for Neurodegeneration
title_short Biomolecular Approaches and Drugs for Neurodegeneration
title_sort biomolecular approaches and drugs for neurodegeneration
topic Neurodegeneration
Drug discovery
Neurodisease
Alzheimer disease
Parkinson&rsquo
S disease
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet Neurodegeneration
Drug discovery
Neurodisease
Alzheimer disease
Parkinson&rsquo
S disease
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url ONIX_20260416T142754_9783725861934_20