Effects of Environmental Exposure on Host and Microbial Metabolism

Trillions of microorganisms, collectively known as the gut microbiota, reside in our gastrointestinal tract and play an essential role in human health and disease. The gut microbiota can be disrupted by various factors, including environmental exposure. Disruptions of the gut microbiota by environme...

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Język:angielski
Wydane: MDPI - Multidisciplinary Digital Publishing Institute 2026
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description Trillions of microorganisms, collectively known as the gut microbiota, reside in our gastrointestinal tract and play an essential role in human health and disease. The gut microbiota can be disrupted by various factors, including environmental exposure. Disruptions of the gut microbiota by environmental exposure may exert adverse effects on human health by affecting host metabolism, intrinsic microbial metabolism, and gut microbiota–host co-metabolism. This Reprint investigates a wide spectrum of these influences, from emerging environmental pollutants like microplastics, per- and polyfluoroalkyl substances, and bisphenol S to traditional contaminants such as fluoride and epoxiconazole fungicide. It also evaluates the role of dietary factors, including non-caloric sweeteners, probiotics, prebiotics, and natural compounds. The research compiled here marks a significant advance in deciphering the complex relationship between our environment, our metabolism, and our microbial inhabitants. These findings are crucial in unraveling the intricate metabolic processes that shape both human health and the dynamics of our microbial partners. While these findings are pivotal, they also underscore the need for further research to establish the causal roles of the gut microbiota in disease development and progression. A deeper understanding of these interdependencies is essential to guide the development of precise and effective strategies for disease prevention and treatment.
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spelling doab-20.500.12854ir-1752322026-04-16T19:43:02Z Effects of Environmental Exposure on Host and Microbial Metabolism Tu, Pengcheng Gao, Bei Metabolomics Environmental exposure Gut microbiota thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCV Economics of specific sectors::KCVG Environmental economics Trillions of microorganisms, collectively known as the gut microbiota, reside in our gastrointestinal tract and play an essential role in human health and disease. The gut microbiota can be disrupted by various factors, including environmental exposure. Disruptions of the gut microbiota by environmental exposure may exert adverse effects on human health by affecting host metabolism, intrinsic microbial metabolism, and gut microbiota–host co-metabolism. This Reprint investigates a wide spectrum of these influences, from emerging environmental pollutants like microplastics, per- and polyfluoroalkyl substances, and bisphenol S to traditional contaminants such as fluoride and epoxiconazole fungicide. It also evaluates the role of dietary factors, including non-caloric sweeteners, probiotics, prebiotics, and natural compounds. The research compiled here marks a significant advance in deciphering the complex relationship between our environment, our metabolism, and our microbial inhabitants. These findings are crucial in unraveling the intricate metabolic processes that shape both human health and the dynamics of our microbial partners. While these findings are pivotal, they also underscore the need for further research to establish the causal roles of the gut microbiota in disease development and progression. A deeper understanding of these interdependencies is essential to guide the development of precise and effective strategies for disease prevention and treatment. 2026-04-16T19:42:54Z 2026-04-16T19:42:54Z 2026 book ONIX_20260416T142754_9783725861736_37 9783725861736 9783725861743 https://directory.doabooks.org/handle/20.500.12854/175232 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/ https://mdpi.com/books/pdfview/book/12144 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-6174-3 10.3390/books978-3-7258-6174-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725861736 9783725861743 232 CH open access
spellingShingle Metabolomics
Environmental exposure
Gut microbiota
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCV Economics of specific sectors::KCVG Environmental economics
Effects of Environmental Exposure on Host and Microbial Metabolism
title Effects of Environmental Exposure on Host and Microbial Metabolism
title_full Effects of Environmental Exposure on Host and Microbial Metabolism
title_fullStr Effects of Environmental Exposure on Host and Microbial Metabolism
title_full_unstemmed Effects of Environmental Exposure on Host and Microbial Metabolism
title_short Effects of Environmental Exposure on Host and Microbial Metabolism
title_sort effects of environmental exposure on host and microbial metabolism
topic Metabolomics
Environmental exposure
Gut microbiota
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCV Economics of specific sectors::KCVG Environmental economics
topic_facet Metabolomics
Environmental exposure
Gut microbiota
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCV Economics of specific sectors::KCVG Environmental economics
url ONIX_20260416T142754_9783725861736_37