Evolution of Treatments of Prostate Cancer
The management of prostate cancer has evolved significantly due to advances in imaging, molecular biology, and therapy. Historically, treatment options were limited to radical prostatectomy and conventional radiotherapy. Today, radiotherapy employs precise image-guided and intensity-modulated techni...
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| 格式: | Online |
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| 語言: | 英语 |
| 出版: |
MDPI - Multidisciplinary Digital Publishing Institute
2026
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| 主題: | |
| 在線閱讀: | ONIX_20260416T142754_9783725860654_42 |
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| _version_ | 1869523539999064064 |
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| collection | Directory of Open Access Books |
| description | The management of prostate cancer has evolved significantly due to advances in imaging, molecular biology, and therapy. Historically, treatment options were limited to radical prostatectomy and conventional radiotherapy. Today, radiotherapy employs precise image-guided and intensity-modulated techniques, such as IMRT and VMAT, which deliver higher tumor doses with reduced toxicity. Innovations like IGRT and SBRT have improved targeting accuracy, enabling hypofractionated regimens that achieve excellent tumor control. Emerging approaches, including MRI-guided radiotherapy and proton therapy, offer even greater precision. Focal therapies—such as HIFU, cryotherapy, and irreversible electroporation—target only the cancerous areas of the prostate, aiming to balance oncologic control with preservation of quality of life. Precision medicine is further transforming care through genomic profiling and molecular imaging (e.g., PSMA-PET), enhancing risk stratification and personalizing treatment. Novel systemic therapies, including PARP inhibitors, androgen receptor–targeted agents, and radioligand therapies, provide new options for patients with advanced disease. Overall, the integration of advanced radiotherapy techniques, focal therapies, and precision medicine is reshaping prostate cancer management, improving outcomes and quality of life. |
| format | Online |
| id | doab-20.500.12854ir-175237 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2026 |
| publishDateRange | 2026 |
| publishDateSort | 2026 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1752372026-04-16T19:44:30Z Evolution of Treatments of Prostate Cancer Munoz, Fernando Prostate cancer Radiation therapy Technical evolution Quality assurance thema EDItEUR::M Medicine and Nursing The management of prostate cancer has evolved significantly due to advances in imaging, molecular biology, and therapy. Historically, treatment options were limited to radical prostatectomy and conventional radiotherapy. Today, radiotherapy employs precise image-guided and intensity-modulated techniques, such as IMRT and VMAT, which deliver higher tumor doses with reduced toxicity. Innovations like IGRT and SBRT have improved targeting accuracy, enabling hypofractionated regimens that achieve excellent tumor control. Emerging approaches, including MRI-guided radiotherapy and proton therapy, offer even greater precision. Focal therapies—such as HIFU, cryotherapy, and irreversible electroporation—target only the cancerous areas of the prostate, aiming to balance oncologic control with preservation of quality of life. Precision medicine is further transforming care through genomic profiling and molecular imaging (e.g., PSMA-PET), enhancing risk stratification and personalizing treatment. Novel systemic therapies, including PARP inhibitors, androgen receptor–targeted agents, and radioligand therapies, provide new options for patients with advanced disease. Overall, the integration of advanced radiotherapy techniques, focal therapies, and precision medicine is reshaping prostate cancer management, improving outcomes and quality of life. 2026-04-16T19:44:23Z 2026-04-16T19:44:23Z 2026 book ONIX_20260416T142754_9783725860654_42 9783725860654 9783725860661 https://directory.doabooks.org/handle/20.500.12854/175237 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/ https://mdpi.com/books/pdfview/book/12149 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-6066-1 10.3390/books978-3-7258-6066-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725860654 9783725860661 122 CH open access |
| spellingShingle | Prostate cancer Radiation therapy Technical evolution Quality assurance thema EDItEUR::M Medicine and Nursing Evolution of Treatments of Prostate Cancer |
| title | Evolution of Treatments of Prostate Cancer |
| title_full | Evolution of Treatments of Prostate Cancer |
| title_fullStr | Evolution of Treatments of Prostate Cancer |
| title_full_unstemmed | Evolution of Treatments of Prostate Cancer |
| title_short | Evolution of Treatments of Prostate Cancer |
| title_sort | evolution of treatments of prostate cancer |
| topic | Prostate cancer Radiation therapy Technical evolution Quality assurance thema EDItEUR::M Medicine and Nursing |
| topic_facet | Prostate cancer Radiation therapy Technical evolution Quality assurance thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20260416T142754_9783725860654_42 |