Hydrogels with Appropriate/Tunable Properties for Biomedical Applications
Initially, hydrogels mainly attracted attention from biomaterial scientists due to their porosity, high water ratio, and soft consistency, which closely simulates natural living tissue. In addition to these features, more properties have been and are being developed to increase their potential for u...
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| स्वरूप: | Online |
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| भाषा: | अंग्रेज़ी |
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MDPI - Multidisciplinary Digital Publishing Institute
2026
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| ऑनलाइन पहुंच: | ONIX_20260416T142754_9783725863884_9 |
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| collection | Directory of Open Access Books |
| description | Initially, hydrogels mainly attracted attention from biomaterial scientists due to their porosity, high water ratio, and soft consistency, which closely simulates natural living tissue. In addition to these features, more properties have been and are being developed to increase their potential for use in biomedical applications, including high mechanical strength, controllable degradation, bioadhesion properties, stimulation responsiveness, and so on. Although much work has been done to endow hydrogels with different properties, it seems that excessive attention has been paid to increasing the 'intensity' of their different properties. Appropriate properties vary in importance based on the specific application. Moderate but not high adhesion strength for bioadhesive-based wound dressings will allow the re-change or re-exposure of wounds to occur more easily. For hydrogel scaffolds, a proper degradation speed that matches the tissue healing speed will lead to a better outcome. For applications in different tissues, hydrogels are needed with various mechanical strengths, rather than just high strength. Additionally, stretchable, light-responsive, and conductive hydrogels are appreciated in flexible and smart devices. Fabricating hydrogels with appropriate/tunable properties is vital to expanding their applications in the biomedical field. |
| format | Online |
| id | doab-20.500.12854ir-175254 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2026 |
| publishDateRange | 2026 |
| publishDateSort | 2026 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1752542026-04-16T19:54:40Z Hydrogels with Appropriate/Tunable Properties for Biomedical Applications Bu, Yazhong Yang, Yanyu Sun, Feifei Konjac glucomannan Solid-state mechanochemical reaction Swelling and disintegration property Fourier-transform infrared spectral change Polymer matrix tablets Sustained drug release kinetics PVA Bi2O3 WO3 BaSO4 X-ray Gamma Shielding XCOM PHITS Simulation Self-assembling peptide hydrogels Intervertebral disc Tissue engineering Hydrogel Chondroitin sulfate Endothelial cell Angiogenesis Hyperlipidaemia Simvastatin Improved therapeutic efficiency Transdermal hydrogel Star-shaped polymer Polypeptide Topology Stimulus-responsive Smart hydrogels Bone defects repair Double network Mechanical property Freeze-resistant Strain sensor Polymeric gels Diffusion EPR spectroscopy Nitroxides Stimuli-responsive hydrogels Traumatic brain injury Biomedical applications Therapeutic mechanisms Hydrogels Curved shell Biomedical devices Phase field Bone tissue engineering Bioactive glass Hybrid hydrogel High mechanics Injectability Peptide assembly Hydroxyapatite Osteoinductive Mimetic bone matrix Bone regenerative engineering Collagen gel Extracellular matrix Stiffness Genipin Cell culture Cell morphology YAP Mesenchymal stromal cells Cancer cells Differentiation Silk hydrogel scaffold Aligned porous structure Freeze-casting Photo-crosslinking Lecithin Scanning electron microscopy Transport properties Model drugs Biopolymer Magnetic microbead Adsorption Photodegradation Photocatalyst N A thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Initially, hydrogels mainly attracted attention from biomaterial scientists due to their porosity, high water ratio, and soft consistency, which closely simulates natural living tissue. In addition to these features, more properties have been and are being developed to increase their potential for use in biomedical applications, including high mechanical strength, controllable degradation, bioadhesion properties, stimulation responsiveness, and so on. Although much work has been done to endow hydrogels with different properties, it seems that excessive attention has been paid to increasing the 'intensity' of their different properties. Appropriate properties vary in importance based on the specific application. Moderate but not high adhesion strength for bioadhesive-based wound dressings will allow the re-change or re-exposure of wounds to occur more easily. For hydrogel scaffolds, a proper degradation speed that matches the tissue healing speed will lead to a better outcome. For applications in different tissues, hydrogels are needed with various mechanical strengths, rather than just high strength. Additionally, stretchable, light-responsive, and conductive hydrogels are appreciated in flexible and smart devices. Fabricating hydrogels with appropriate/tunable properties is vital to expanding their applications in the biomedical field. 2026-04-16T19:54:32Z 2026-04-16T19:54:32Z 2026 book ONIX_20260416T142754_9783725863884_9 9783725863884 9783725863891 https://directory.doabooks.org/handle/20.500.12854/175254 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/ https://mdpi.com/books/pdfview/book/12166 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-6389-1 10.3390/books978-3-7258-6389-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725863884 9783725863891 292 CH open access |
| spellingShingle | Konjac glucomannan Solid-state mechanochemical reaction Swelling and disintegration property Fourier-transform infrared spectral change Polymer matrix tablets Sustained drug release kinetics PVA Bi2O3 WO3 BaSO4 X-ray Gamma Shielding XCOM PHITS Simulation Self-assembling peptide hydrogels Intervertebral disc Tissue engineering Hydrogel Chondroitin sulfate Endothelial cell Angiogenesis Hyperlipidaemia Simvastatin Improved therapeutic efficiency Transdermal hydrogel Star-shaped polymer Polypeptide Topology Stimulus-responsive Smart hydrogels Bone defects repair Double network Mechanical property Freeze-resistant Strain sensor Polymeric gels Diffusion EPR spectroscopy Nitroxides Stimuli-responsive hydrogels Traumatic brain injury Biomedical applications Therapeutic mechanisms Hydrogels Curved shell Biomedical devices Phase field Bone tissue engineering Bioactive glass Hybrid hydrogel High mechanics Injectability Peptide assembly Hydroxyapatite Osteoinductive Mimetic bone matrix Bone regenerative engineering Collagen gel Extracellular matrix Stiffness Genipin Cell culture Cell morphology YAP Mesenchymal stromal cells Cancer cells Differentiation Silk hydrogel scaffold Aligned porous structure Freeze-casting Photo-crosslinking Lecithin Scanning electron microscopy Transport properties Model drugs Biopolymer Magnetic microbead Adsorption Photodegradation Photocatalyst N A thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Hydrogels with Appropriate/Tunable Properties for Biomedical Applications |
| title | Hydrogels with Appropriate/Tunable Properties for Biomedical Applications |
| title_full | Hydrogels with Appropriate/Tunable Properties for Biomedical Applications |
| title_fullStr | Hydrogels with Appropriate/Tunable Properties for Biomedical Applications |
| title_full_unstemmed | Hydrogels with Appropriate/Tunable Properties for Biomedical Applications |
| title_short | Hydrogels with Appropriate/Tunable Properties for Biomedical Applications |
| title_sort | hydrogels with appropriate tunable properties for biomedical applications |
| topic | Konjac glucomannan Solid-state mechanochemical reaction Swelling and disintegration property Fourier-transform infrared spectral change Polymer matrix tablets Sustained drug release kinetics PVA Bi2O3 WO3 BaSO4 X-ray Gamma Shielding XCOM PHITS Simulation Self-assembling peptide hydrogels Intervertebral disc Tissue engineering Hydrogel Chondroitin sulfate Endothelial cell Angiogenesis Hyperlipidaemia Simvastatin Improved therapeutic efficiency Transdermal hydrogel Star-shaped polymer Polypeptide Topology Stimulus-responsive Smart hydrogels Bone defects repair Double network Mechanical property Freeze-resistant Strain sensor Polymeric gels Diffusion EPR spectroscopy Nitroxides Stimuli-responsive hydrogels Traumatic brain injury Biomedical applications Therapeutic mechanisms Hydrogels Curved shell Biomedical devices Phase field Bone tissue engineering Bioactive glass Hybrid hydrogel High mechanics Injectability Peptide assembly Hydroxyapatite Osteoinductive Mimetic bone matrix Bone regenerative engineering Collagen gel Extracellular matrix Stiffness Genipin Cell culture Cell morphology YAP Mesenchymal stromal cells Cancer cells Differentiation Silk hydrogel scaffold Aligned porous structure Freeze-casting Photo-crosslinking Lecithin Scanning electron microscopy Transport properties Model drugs Biopolymer Magnetic microbead Adsorption Photodegradation Photocatalyst N A thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | Konjac glucomannan Solid-state mechanochemical reaction Swelling and disintegration property Fourier-transform infrared spectral change Polymer matrix tablets Sustained drug release kinetics PVA Bi2O3 WO3 BaSO4 X-ray Gamma Shielding XCOM PHITS Simulation Self-assembling peptide hydrogels Intervertebral disc Tissue engineering Hydrogel Chondroitin sulfate Endothelial cell Angiogenesis Hyperlipidaemia Simvastatin Improved therapeutic efficiency Transdermal hydrogel Star-shaped polymer Polypeptide Topology Stimulus-responsive Smart hydrogels Bone defects repair Double network Mechanical property Freeze-resistant Strain sensor Polymeric gels Diffusion EPR spectroscopy Nitroxides Stimuli-responsive hydrogels Traumatic brain injury Biomedical applications Therapeutic mechanisms Hydrogels Curved shell Biomedical devices Phase field Bone tissue engineering Bioactive glass Hybrid hydrogel High mechanics Injectability Peptide assembly Hydroxyapatite Osteoinductive Mimetic bone matrix Bone regenerative engineering Collagen gel Extracellular matrix Stiffness Genipin Cell culture Cell morphology YAP Mesenchymal stromal cells Cancer cells Differentiation Silk hydrogel scaffold Aligned porous structure Freeze-casting Photo-crosslinking Lecithin Scanning electron microscopy Transport properties Model drugs Biopolymer Magnetic microbead Adsorption Photodegradation Photocatalyst N A thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20260416T142754_9783725863884_9 |