Dietary Supplements in Human Health and Disease
This Reprint brings together a curated selection of recent studies investigating the role of dietary supplements and naturally derived bioactive compounds in supporting human health. The contributions examine both potential benefits and safety considerations, with particular attention to mechanisms...
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| Format: | Online |
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| Jezik: | engleski |
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MDPI - Multidisciplinary Digital Publishing Institute
2026
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| Teme: | |
| Online pristup: | ONIX_20260416T142754_9783725866946_48 |
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| _version_ | 1869522240056328192 |
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| collection | Directory of Open Access Books |
| description | This Reprint brings together a curated selection of recent studies investigating the role of dietary supplements and naturally derived bioactive compounds in supporting human health. The contributions examine both potential benefits and safety considerations, with particular attention to mechanisms of action, interactions with physiological and pathological processes, and implications for clinical or functional applications. The articles encompass a broad spectrum of topics, including plant extracts with estrogen-like activity for the management of menopausal symptoms; myo-inositol supplementation for anxiety; epigenetic alterations induced by high-fat diets, highlighting EZH2 as a potential pharmacological target in metabolic dysfunction; and a comprehensive evaluation of the composition, bioaccessibility, pharmacokinetic interactions, and cellular effects of berberine-containing botanicals. Additional studies explore the therapeutic potential of purple corn extract in dry eye disease and the antiadipogenic activity of Euscaphis japonica fruit extract in models of adipocyte differentiation. Two further contributions investigate the impact of natural compounds in humans, examining the effect of mulberry fruit extract on postprandial glycemia in individuals with type 2 diabetes and the influence of lutein supplementation—both in free and esterified forms—on visual outcomes in healthy subjects. Together, these studies offer an integrated perspective on the opportunities and limitations of dietary supplements, underscoring the need for rigorous experimental and clinical approaches to assess their efficacy safety in human health. |
| format | Online |
| id | doab-20.500.12854ir-175343 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2026 |
| publishDateRange | 2026 |
| publishDateSort | 2026 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1753432026-04-16T20:20:44Z Dietary Supplements in Human Health and Disease Benetti, Elisa Boscaro, Valentina Euscaphis japonica Kanitz fruit Antiobesity Adipogenesis 3T3-L1 preadipocytes Mitotic clonal expansion (MCE) Dry eye disease Purple corn extract Anthocyanin Cyanidin-3-O-glucoside Inflammation Regulated cell death Lutein intake Blood lutein Lutein free Lutein ester Contrast sensitivity Zeaxanthin Myo-Inositol Anxiety Anxiolytics Zebrafish Alpha-glucosidase 1-deoxynojirimycin Glycemic control Starch Rice Berberine Safety Bioaccessibility Cell viability Gene expression High-fat diet H3K27 trimethylation Methyltransferase EZH2 Menopause Styphnolobium japonicum fruit Germinated soybean embryo Ovariectomized rat model Phytoestrogen Medicinal plant thema EDItEUR::P Mathematics and Science::PS Biology, life sciences This Reprint brings together a curated selection of recent studies investigating the role of dietary supplements and naturally derived bioactive compounds in supporting human health. The contributions examine both potential benefits and safety considerations, with particular attention to mechanisms of action, interactions with physiological and pathological processes, and implications for clinical or functional applications. The articles encompass a broad spectrum of topics, including plant extracts with estrogen-like activity for the management of menopausal symptoms; myo-inositol supplementation for anxiety; epigenetic alterations induced by high-fat diets, highlighting EZH2 as a potential pharmacological target in metabolic dysfunction; and a comprehensive evaluation of the composition, bioaccessibility, pharmacokinetic interactions, and cellular effects of berberine-containing botanicals. Additional studies explore the therapeutic potential of purple corn extract in dry eye disease and the antiadipogenic activity of Euscaphis japonica fruit extract in models of adipocyte differentiation. Two further contributions investigate the impact of natural compounds in humans, examining the effect of mulberry fruit extract on postprandial glycemia in individuals with type 2 diabetes and the influence of lutein supplementation—both in free and esterified forms—on visual outcomes in healthy subjects. Together, these studies offer an integrated perspective on the opportunities and limitations of dietary supplements, underscoring the need for rigorous experimental and clinical approaches to assess their efficacy safety in human health. 2026-04-16T20:20:34Z 2026-04-16T20:20:34Z 2026 book ONIX_20260416T142754_9783725866946_48 9783725866946 9783725866953 https://directory.doabooks.org/handle/20.500.12854/175343 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/ https://mdpi.com/books/pdfview/book/12258 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-6695-3 10.3390/books978-3-7258-6695-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725866946 9783725866953 130 CH open access |
| spellingShingle | Euscaphis japonica Kanitz fruit Antiobesity Adipogenesis 3T3-L1 preadipocytes Mitotic clonal expansion (MCE) Dry eye disease Purple corn extract Anthocyanin Cyanidin-3-O-glucoside Inflammation Regulated cell death Lutein intake Blood lutein Lutein free Lutein ester Contrast sensitivity Zeaxanthin Myo-Inositol Anxiety Anxiolytics Zebrafish Alpha-glucosidase 1-deoxynojirimycin Glycemic control Starch Rice Berberine Safety Bioaccessibility Cell viability Gene expression High-fat diet H3K27 trimethylation Methyltransferase EZH2 Menopause Styphnolobium japonicum fruit Germinated soybean embryo Ovariectomized rat model Phytoestrogen Medicinal plant thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Dietary Supplements in Human Health and Disease |
| title | Dietary Supplements in Human Health and Disease |
| title_full | Dietary Supplements in Human Health and Disease |
| title_fullStr | Dietary Supplements in Human Health and Disease |
| title_full_unstemmed | Dietary Supplements in Human Health and Disease |
| title_short | Dietary Supplements in Human Health and Disease |
| title_sort | dietary supplements in human health and disease |
| topic | Euscaphis japonica Kanitz fruit Antiobesity Adipogenesis 3T3-L1 preadipocytes Mitotic clonal expansion (MCE) Dry eye disease Purple corn extract Anthocyanin Cyanidin-3-O-glucoside Inflammation Regulated cell death Lutein intake Blood lutein Lutein free Lutein ester Contrast sensitivity Zeaxanthin Myo-Inositol Anxiety Anxiolytics Zebrafish Alpha-glucosidase 1-deoxynojirimycin Glycemic control Starch Rice Berberine Safety Bioaccessibility Cell viability Gene expression High-fat diet H3K27 trimethylation Methyltransferase EZH2 Menopause Styphnolobium japonicum fruit Germinated soybean embryo Ovariectomized rat model Phytoestrogen Medicinal plant thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | Euscaphis japonica Kanitz fruit Antiobesity Adipogenesis 3T3-L1 preadipocytes Mitotic clonal expansion (MCE) Dry eye disease Purple corn extract Anthocyanin Cyanidin-3-O-glucoside Inflammation Regulated cell death Lutein intake Blood lutein Lutein free Lutein ester Contrast sensitivity Zeaxanthin Myo-Inositol Anxiety Anxiolytics Zebrafish Alpha-glucosidase 1-deoxynojirimycin Glycemic control Starch Rice Berberine Safety Bioaccessibility Cell viability Gene expression High-fat diet H3K27 trimethylation Methyltransferase EZH2 Menopause Styphnolobium japonicum fruit Germinated soybean embryo Ovariectomized rat model Phytoestrogen Medicinal plant thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20260416T142754_9783725866946_48 |