Assessing Complexity in Physiological Systems through Biomedical Signals Analysis II

Most physiological systems behave like complex, adaptive structures. In physiology and medicine, this complexity reflects the capacity of living systems to maintain homeostasis while responding to internal and external challenges, arising from features such as fractal- and self-organization, nonline...

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Published: MDPI - Multidisciplinary Digital Publishing Institute 2026
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collection Directory of Open Access Books
description Most physiological systems behave like complex, adaptive structures. In physiology and medicine, this complexity reflects the capacity of living systems to maintain homeostasis while responding to internal and external challenges, arising from features such as fractal- and self-organization, nonlinear dynamics, and the coordinated activity of interdependent components operating across multiple hierarchical levels and time scales. Biomedical signals encode aspects of this complexity, supporting the identification of physiological states, long-term health monitoring, and the anticipation of pathological events. As a result, contemporary research has focused on methods capable of characterizing system complexity in time series derived from continuous electroencephalogram and electromyogram recordings, cardiovascular beat-by-beat measurements, respiratory patterns, and other physiological variables. Despite substantial progress, key methodological challenges remain, including differentiating complexity from randomness, ensuring robust estimation from short or multivariate recordings, integrating multivariate measures of predictability, entropy, and fractality, and describing the underlying stochastic processes. This Reprint is the second volume in its series, following the initial Entropy Special Issue printed in 2021. Building on the significant interest generated by that collection, this volume presents recent studies which aimed to enhance the applications of complexity-based methods in physiological and clinical contexts.
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publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-1753972026-04-16T20:41:50Z Assessing Complexity in Physiological Systems through Biomedical Signals Analysis II Castiglioni, Paolo Faes, Luca Valenza, Gaetano Faini, Andrea Heart rate variability Inhibitory control Complexity index Entropy Multiscale entropy Spinal cord injury Posture Autonomic nervous system SampEn FuzzyEn DistEn Visibility Tachograms K-M slope Complex networks Average degree Average path length Baroreflex Blood pressure regulation Cardiovascular dynamics Homeostasis Fractal Self-organized criticality Soccer Zipf’s law Fractal dimension Box-counting EEG Parkinson’s disease Neurodegeneration Cardiovascular Multifractality DFA Autonomic control Heart–brain Central autonomic network Cognitive task Detrended fluctuation analysis Multifractal Multiscale analysis Cycling Tetris Multifractal cumulative function Legendre spectrum Electroencephalography (EEG) Multi-entropy fusion Brain rhythms Single-channel Emotion recognition Schizophrenia Electroencephalography Higuchi fractal dimension Neural complexity Temporal dynamics Spike train Artificial neural networks Biological neurons Intermittency Criticality Tricriticality Phase transitions Stockwell transform Stockwell entropy Common spatial pattern Parameterized PSD Aperiodic component Periodic component Specific language impairment Network physiology Functional near-infrared spectroscopy Power spectral density Information dynamics Time-resolved analysis Time-varying autoregressive modeling Recursive least-squares N A thema EDItEUR::M Medicine and Nursing Most physiological systems behave like complex, adaptive structures. In physiology and medicine, this complexity reflects the capacity of living systems to maintain homeostasis while responding to internal and external challenges, arising from features such as fractal- and self-organization, nonlinear dynamics, and the coordinated activity of interdependent components operating across multiple hierarchical levels and time scales. Biomedical signals encode aspects of this complexity, supporting the identification of physiological states, long-term health monitoring, and the anticipation of pathological events. As a result, contemporary research has focused on methods capable of characterizing system complexity in time series derived from continuous electroencephalogram and electromyogram recordings, cardiovascular beat-by-beat measurements, respiratory patterns, and other physiological variables. Despite substantial progress, key methodological challenges remain, including differentiating complexity from randomness, ensuring robust estimation from short or multivariate recordings, integrating multivariate measures of predictability, entropy, and fractality, and describing the underlying stochastic processes. This Reprint is the second volume in its series, following the initial Entropy Special Issue printed in 2021. Building on the significant interest generated by that collection, this volume presents recent studies which aimed to enhance the applications of complexity-based methods in physiological and clinical contexts. 2026-04-16T20:41:41Z 2026-04-16T20:41:41Z 2026 book ONIX_20260416T142754_9783725863662_2 9783725863662 9783725863679 https://directory.doabooks.org/handle/20.500.12854/175397 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/ https://mdpi.com/books/pdfview/book/12315 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-6367-9 10.3390/books978-3-7258-6367-9 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725863662 9783725863679 218 CH open access
spellingShingle Heart rate variability
Inhibitory control
Complexity index
Entropy
Multiscale entropy
Spinal cord injury
Posture
Autonomic nervous system
SampEn
FuzzyEn
DistEn
Visibility
Tachograms
K-M slope
Complex networks
Average degree
Average path length
Baroreflex
Blood pressure regulation
Cardiovascular dynamics
Homeostasis
Fractal
Self-organized criticality
Soccer
Zipf’s law
Fractal dimension
Box-counting
EEG
Parkinson’s disease
Neurodegeneration
Cardiovascular
Multifractality
DFA
Autonomic control
Heart–brain
Central autonomic network
Cognitive task
Detrended fluctuation analysis
Multifractal
Multiscale analysis
Cycling
Tetris
Multifractal cumulative function
Legendre spectrum
Electroencephalography (EEG)
Multi-entropy fusion
Brain rhythms
Single-channel
Emotion recognition
Schizophrenia
Electroencephalography
Higuchi fractal dimension
Neural complexity
Temporal dynamics
Spike train
Artificial neural networks
Biological neurons
Intermittency
Criticality
Tricriticality
Phase transitions
Stockwell transform
Stockwell entropy
Common spatial pattern
Parameterized PSD
Aperiodic component
Periodic component
Specific language impairment
Network physiology
Functional near-infrared spectroscopy
Power spectral density
Information dynamics
Time-resolved analysis
Time-varying autoregressive modeling
Recursive least-squares
N
A
thema EDItEUR::M Medicine and Nursing
Assessing Complexity in Physiological Systems through Biomedical Signals Analysis II
title Assessing Complexity in Physiological Systems through Biomedical Signals Analysis II
title_full Assessing Complexity in Physiological Systems through Biomedical Signals Analysis II
title_fullStr Assessing Complexity in Physiological Systems through Biomedical Signals Analysis II
title_full_unstemmed Assessing Complexity in Physiological Systems through Biomedical Signals Analysis II
title_short Assessing Complexity in Physiological Systems through Biomedical Signals Analysis II
title_sort assessing complexity in physiological systems through biomedical signals analysis ii
topic Heart rate variability
Inhibitory control
Complexity index
Entropy
Multiscale entropy
Spinal cord injury
Posture
Autonomic nervous system
SampEn
FuzzyEn
DistEn
Visibility
Tachograms
K-M slope
Complex networks
Average degree
Average path length
Baroreflex
Blood pressure regulation
Cardiovascular dynamics
Homeostasis
Fractal
Self-organized criticality
Soccer
Zipf’s law
Fractal dimension
Box-counting
EEG
Parkinson’s disease
Neurodegeneration
Cardiovascular
Multifractality
DFA
Autonomic control
Heart–brain
Central autonomic network
Cognitive task
Detrended fluctuation analysis
Multifractal
Multiscale analysis
Cycling
Tetris
Multifractal cumulative function
Legendre spectrum
Electroencephalography (EEG)
Multi-entropy fusion
Brain rhythms
Single-channel
Emotion recognition
Schizophrenia
Electroencephalography
Higuchi fractal dimension
Neural complexity
Temporal dynamics
Spike train
Artificial neural networks
Biological neurons
Intermittency
Criticality
Tricriticality
Phase transitions
Stockwell transform
Stockwell entropy
Common spatial pattern
Parameterized PSD
Aperiodic component
Periodic component
Specific language impairment
Network physiology
Functional near-infrared spectroscopy
Power spectral density
Information dynamics
Time-resolved analysis
Time-varying autoregressive modeling
Recursive least-squares
N
A
thema EDItEUR::M Medicine and Nursing
topic_facet Heart rate variability
Inhibitory control
Complexity index
Entropy
Multiscale entropy
Spinal cord injury
Posture
Autonomic nervous system
SampEn
FuzzyEn
DistEn
Visibility
Tachograms
K-M slope
Complex networks
Average degree
Average path length
Baroreflex
Blood pressure regulation
Cardiovascular dynamics
Homeostasis
Fractal
Self-organized criticality
Soccer
Zipf’s law
Fractal dimension
Box-counting
EEG
Parkinson’s disease
Neurodegeneration
Cardiovascular
Multifractality
DFA
Autonomic control
Heart–brain
Central autonomic network
Cognitive task
Detrended fluctuation analysis
Multifractal
Multiscale analysis
Cycling
Tetris
Multifractal cumulative function
Legendre spectrum
Electroencephalography (EEG)
Multi-entropy fusion
Brain rhythms
Single-channel
Emotion recognition
Schizophrenia
Electroencephalography
Higuchi fractal dimension
Neural complexity
Temporal dynamics
Spike train
Artificial neural networks
Biological neurons
Intermittency
Criticality
Tricriticality
Phase transitions
Stockwell transform
Stockwell entropy
Common spatial pattern
Parameterized PSD
Aperiodic component
Periodic component
Specific language impairment
Network physiology
Functional near-infrared spectroscopy
Power spectral density
Information dynamics
Time-resolved analysis
Time-varying autoregressive modeling
Recursive least-squares
N
A
thema EDItEUR::M Medicine and Nursing
url ONIX_20260416T142754_9783725863662_2