New Challenges of Parkinson’s Disease
An early and accurate diagnosis for Parkinson’s disease (PD) is essential not only for improving prognostic outcomes but also for enabling timely therapeutic interventions. Nevertheless, achieving early diagnosis remains difficult because the characteristic symptoms of PD frequently overlap with tho...
Tallennettuna:
| Aineistotyyppi: | Online |
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| Kieli: | englanti |
| Julkaistu: |
MDPI - Multidisciplinary Digital Publishing Institute
2026
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| Aiheet: | |
| Linkit: | ONIX_20260416T142754_9783725862740_10 |
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| _version_ | 1869529166964064256 |
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| collection | Directory of Open Access Books |
| description | An early and accurate diagnosis for Parkinson’s disease (PD) is essential not only for improving prognostic outcomes but also for enabling timely therapeutic interventions. Nevertheless, achieving early diagnosis remains difficult because the characteristic symptoms of PD frequently overlap with those of other neurodegenerative disorders. In addition, current diagnostic approaches rely heavily on clinical evaluation, underscoring the need for more precise, objective methods. In this scenario, the discovery and validation of robust biomarkers have become increasingly important, as they can aid in differential diagnosis, track disease progression, and inform the development of personalized therapies—ultimately enhancing patient management and quality of life. This Reprint of the Special Issue of the International Journal of Molecular Sciences features four reviews and six original research articles that explore new challenges in understanding, diagnosing, and treating Parkinson’s disease. The contributions in this issue cover a broad spectrum of topics, ranging from the identification of biochemical, genetic, and epigenetic biomarkers to the application of advanced approaches, including multi-omics integration, artificial intelligence, and functional imaging. Particular attention is also given to the innovative use of extracellular vesicles (EVs) and to emerging therapeutic strategies. |
| format | Online |
| id | doab-20.500.12854ir-175405 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2026 |
| publishDateRange | 2026 |
| publishDateSort | 2026 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1754052026-04-16T20:44:22Z New Challenges of Parkinson’s Disease Agliardi, Cristina Guerini, Franca Rosa Parkinson&rsquo S disease Biomarker Animal model Diagnosis Progression thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences An early and accurate diagnosis for Parkinson’s disease (PD) is essential not only for improving prognostic outcomes but also for enabling timely therapeutic interventions. Nevertheless, achieving early diagnosis remains difficult because the characteristic symptoms of PD frequently overlap with those of other neurodegenerative disorders. In addition, current diagnostic approaches rely heavily on clinical evaluation, underscoring the need for more precise, objective methods. In this scenario, the discovery and validation of robust biomarkers have become increasingly important, as they can aid in differential diagnosis, track disease progression, and inform the development of personalized therapies—ultimately enhancing patient management and quality of life. This Reprint of the Special Issue of the International Journal of Molecular Sciences features four reviews and six original research articles that explore new challenges in understanding, diagnosing, and treating Parkinson’s disease. The contributions in this issue cover a broad spectrum of topics, ranging from the identification of biochemical, genetic, and epigenetic biomarkers to the application of advanced approaches, including multi-omics integration, artificial intelligence, and functional imaging. Particular attention is also given to the innovative use of extracellular vesicles (EVs) and to emerging therapeutic strategies. 2026-04-16T20:44:14Z 2026-04-16T20:44:14Z 2026 book ONIX_20260416T142754_9783725862740_10 9783725862740 9783725862757 https://directory.doabooks.org/handle/20.500.12854/175405 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/ https://mdpi.com/books/pdfview/book/12323 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-6275-7 10.3390/books978-3-7258-6275-7 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725862740 9783725862757 188 CH open access |
| spellingShingle | Parkinson&rsquo S disease Biomarker Animal model Diagnosis Progression thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences New Challenges of Parkinson’s Disease |
| title | New Challenges of Parkinson’s Disease |
| title_full | New Challenges of Parkinson’s Disease |
| title_fullStr | New Challenges of Parkinson’s Disease |
| title_full_unstemmed | New Challenges of Parkinson’s Disease |
| title_short | New Challenges of Parkinson’s Disease |
| title_sort | new challenges of parkinson rsquo s disease |
| topic | Parkinson&rsquo S disease Biomarker Animal model Diagnosis Progression thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | Parkinson&rsquo S disease Biomarker Animal model Diagnosis Progression thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20260416T142754_9783725862740_10 |