Recent Advances in Hypertension, Hypercholesterolemia and Type 2 Diabetes

Type 2 diabetes, the most prevalent form of diabetes associated with obesity, remains one of the leading global causes of mortality and disability. Type 2 diabetes is usually clustered with other risk factors associated with metabolic syndrome, such as hypertension and hypercholesterolemia. The cent...

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Pubblicazione: MDPI - Multidisciplinary Digital Publishing Institute 2026
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collection Directory of Open Access Books
description Type 2 diabetes, the most prevalent form of diabetes associated with obesity, remains one of the leading global causes of mortality and disability. Type 2 diabetes is usually clustered with other risk factors associated with metabolic syndrome, such as hypertension and hypercholesterolemia. The central pathophysiological condition connecting these diseases is insulin resistance associated with visceral obesity. Insulin resistance alters systemic lipid metabolism and leads to the development of a characteristic form of dyslipidemia, with high levels of plasma triglycerides, low levels of high-density lipoprotein, and predominance of small, dense low-density lipoprotein. Hypertension is one of the most prevalent chronic conditions worldwide, affecting more than one billion adults and representing a leading risk factor for cardiovascular disease. However, many individuals with hypertension remain undiagnosed, untreated, or inadequately controlled. Strict management of blood pressure, along with optimization of serum lipid levels, body weight, and lifestyle factors such as smoking cessation, is crucial for controlling the global burden of cardiovascular disease and reducing the risk of premature mortality. Although recent trends indicate a decline in all-cause and cardiovascular mortality, the risk remains high, particularly among patients with diabetes. In this context, this Special Issue brings together the latest research and advancements contributing to the understanding and management of hypertension, hypercholesterolemia, and type 2 diabetes.
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spelling doab-20.500.12854ir-1754132026-04-16T20:46:43Z Recent Advances in Hypertension, Hypercholesterolemia and Type 2 Diabetes Bulum, Tomislav Type 1 diabetes Type 2 diabetes Hypercholesterolemia Hypertension Comorbidities Macrovascular complications thema EDItEUR::M Medicine and Nursing Type 2 diabetes, the most prevalent form of diabetes associated with obesity, remains one of the leading global causes of mortality and disability. Type 2 diabetes is usually clustered with other risk factors associated with metabolic syndrome, such as hypertension and hypercholesterolemia. The central pathophysiological condition connecting these diseases is insulin resistance associated with visceral obesity. Insulin resistance alters systemic lipid metabolism and leads to the development of a characteristic form of dyslipidemia, with high levels of plasma triglycerides, low levels of high-density lipoprotein, and predominance of small, dense low-density lipoprotein. Hypertension is one of the most prevalent chronic conditions worldwide, affecting more than one billion adults and representing a leading risk factor for cardiovascular disease. However, many individuals with hypertension remain undiagnosed, untreated, or inadequately controlled. Strict management of blood pressure, along with optimization of serum lipid levels, body weight, and lifestyle factors such as smoking cessation, is crucial for controlling the global burden of cardiovascular disease and reducing the risk of premature mortality. Although recent trends indicate a decline in all-cause and cardiovascular mortality, the risk remains high, particularly among patients with diabetes. In this context, this Special Issue brings together the latest research and advancements contributing to the understanding and management of hypertension, hypercholesterolemia, and type 2 diabetes. 2026-04-16T20:46:37Z 2026-04-16T20:46:37Z 2026 book ONIX_20260416T142754_9783725867660_18 9783725867660 9783725867677 https://directory.doabooks.org/handle/20.500.12854/175413 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/ https://mdpi.com/books/pdfview/book/12331 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-6767-7 10.3390/books978-3-7258-6767-7 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725867660 9783725867677 126 CH open access
spellingShingle Type 1 diabetes
Type 2 diabetes
Hypercholesterolemia
Hypertension
Comorbidities
Macrovascular complications
thema EDItEUR::M Medicine and Nursing
Recent Advances in Hypertension, Hypercholesterolemia and Type 2 Diabetes
title Recent Advances in Hypertension, Hypercholesterolemia and Type 2 Diabetes
title_full Recent Advances in Hypertension, Hypercholesterolemia and Type 2 Diabetes
title_fullStr Recent Advances in Hypertension, Hypercholesterolemia and Type 2 Diabetes
title_full_unstemmed Recent Advances in Hypertension, Hypercholesterolemia and Type 2 Diabetes
title_short Recent Advances in Hypertension, Hypercholesterolemia and Type 2 Diabetes
title_sort recent advances in hypertension hypercholesterolemia and type 2 diabetes
topic Type 1 diabetes
Type 2 diabetes
Hypercholesterolemia
Hypertension
Comorbidities
Macrovascular complications
thema EDItEUR::M Medicine and Nursing
topic_facet Type 1 diabetes
Type 2 diabetes
Hypercholesterolemia
Hypertension
Comorbidities
Macrovascular complications
thema EDItEUR::M Medicine and Nursing
url ONIX_20260416T142754_9783725867660_18