Molecular Mechanisms of Tumor Progression and New Therapeutic Strategies for Urological Cancers, 2nd Edition

Urological tumors include malignancies of the bladder, prostate, kidney, upper urinary tract, and germ cells, among others. Their incidence has increased markedly over the past four decades, and together they account for a substantial proportion of cancers worldwide—up to one third of all malignanci...

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collection Directory of Open Access Books
description Urological tumors include malignancies of the bladder, prostate, kidney, upper urinary tract, and germ cells, among others. Their incidence has increased markedly over the past four decades, and together they account for a substantial proportion of cancers worldwide—up to one third of all malignancies in men. The diversity of their pathogenetic mechanisms and the complexity of their diagnostic and therapeutic management continue to pose major challenges in clinical practice. Treatment selection depends on multiple factors, including tumor grade and stage, with current options encompassing surgery, chemotherapy, radiotherapy, and systemic therapies. In recent years, the therapeutic landscape of urological tumors has evolved significantly with the introduction of immunotherapy and targeted treatments. Nevertheless, a deeper understanding of the molecular mechanisms underlying tumor progression and therapy resistance remains essential for developing novel strategies and optimizing patient outcomes within the framework of precision medicine.This Reprint of the International Journal of Molecular Sciences brings together original research and review articles addressing the molecular mechanisms driving tumor progression and resistance to current therapies, the identification of prognostic and predictive biomarkers, and the exploration of new therapeutic strategies for urological cancers.
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language eng
publishDate 2026
publishDateRange 2026
publishDateSort 2026
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
record_format ojs
spelling doab-20.500.12854ir-1754552026-04-16T21:01:26Z Molecular Mechanisms of Tumor Progression and New Therapeutic Strategies for Urological Cancers, 2nd Edition Ruiz de Porras, Vicenç Font, Albert Prostate cancer Bladder cancer Renal cell carcinoma Penile carcinoma Predictive and prognostic biomarkers Novel treatment strategies Chemotherapy Immunotherapy Target therapies Drug resistance mechanisms thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Urological tumors include malignancies of the bladder, prostate, kidney, upper urinary tract, and germ cells, among others. Their incidence has increased markedly over the past four decades, and together they account for a substantial proportion of cancers worldwide—up to one third of all malignancies in men. The diversity of their pathogenetic mechanisms and the complexity of their diagnostic and therapeutic management continue to pose major challenges in clinical practice. Treatment selection depends on multiple factors, including tumor grade and stage, with current options encompassing surgery, chemotherapy, radiotherapy, and systemic therapies. In recent years, the therapeutic landscape of urological tumors has evolved significantly with the introduction of immunotherapy and targeted treatments. Nevertheless, a deeper understanding of the molecular mechanisms underlying tumor progression and therapy resistance remains essential for developing novel strategies and optimizing patient outcomes within the framework of precision medicine.This Reprint of the International Journal of Molecular Sciences brings together original research and review articles addressing the molecular mechanisms driving tumor progression and resistance to current therapies, the identification of prognostic and predictive biomarkers, and the exploration of new therapeutic strategies for urological cancers. 2026-04-16T21:01:18Z 2026-04-16T21:01:18Z 2026 book ONIX_20260416T142754_9783725866465_10 9783725866465 9783725866472 https://directory.doabooks.org/handle/20.500.12854/175455 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/ https://mdpi.com/books/pdfview/book/12374 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-7258-6647-2 10.3390/books978-3-7258-6647-2 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783725866465 9783725866472 124 CH open access
spellingShingle Prostate cancer
Bladder cancer
Renal cell carcinoma
Penile carcinoma
Predictive and prognostic biomarkers
Novel treatment strategies
Chemotherapy
Immunotherapy
Target therapies
Drug resistance mechanisms
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Molecular Mechanisms of Tumor Progression and New Therapeutic Strategies for Urological Cancers, 2nd Edition
title Molecular Mechanisms of Tumor Progression and New Therapeutic Strategies for Urological Cancers, 2nd Edition
title_full Molecular Mechanisms of Tumor Progression and New Therapeutic Strategies for Urological Cancers, 2nd Edition
title_fullStr Molecular Mechanisms of Tumor Progression and New Therapeutic Strategies for Urological Cancers, 2nd Edition
title_full_unstemmed Molecular Mechanisms of Tumor Progression and New Therapeutic Strategies for Urological Cancers, 2nd Edition
title_short Molecular Mechanisms of Tumor Progression and New Therapeutic Strategies for Urological Cancers, 2nd Edition
title_sort molecular mechanisms of tumor progression and new therapeutic strategies for urological cancers 2nd edition
topic Prostate cancer
Bladder cancer
Renal cell carcinoma
Penile carcinoma
Predictive and prognostic biomarkers
Novel treatment strategies
Chemotherapy
Immunotherapy
Target therapies
Drug resistance mechanisms
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet Prostate cancer
Bladder cancer
Renal cell carcinoma
Penile carcinoma
Predictive and prognostic biomarkers
Novel treatment strategies
Chemotherapy
Immunotherapy
Target therapies
Drug resistance mechanisms
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url ONIX_20260416T142754_9783725866465_10