Magnesium in the Central Nervous System

Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesiu...

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Lenguaje:inglés
Publicado: University of Adelaide Press 2021
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Acceso en línea:560245
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collection Directory of Open Access Books
description Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium in particular remains elusive, largely because intracelluar levls are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesium’s involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behaviour. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesium’s role in biological systems that has inspired the collation of this volume of work.
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spelling doab-20.500.12854ir-264912025-07-30T08:59:12Z Magnesium in the Central Nervous System Vink, Robert Nechifor, Mihai magnesium central nervous system neurological disease psychiatric disease Magnesium thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium in particular remains elusive, largely because intracelluar levls are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesium’s involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behaviour. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesium’s role in biological systems that has inspired the collation of this volume of work. 2021-02-10T12:58:18Z 2015-12-31 23:55:55 2018-06-27 14:41:01 2020-04-01T14:35:16Z 2011 book 560245 OCN: 772689665 http://library.oapen.org/handle/20.500.12657/33167 9780987073051 https://directory.doabooks.org/handle/20.500.12854/26491 eng open access image/jpeg image/jpeg image/jpeg image/jpeg image/jpeg n/a n/a n/a n/a n/a https://library.oapen.org/bitstream/20.500.12657/33167/1/560245.pdf https://library.oapen.org/bitstream/20.500.12657/33167/1/560245.pdf https://library.oapen.org/bitstream/20.500.12657/33167/1/560245.pdf https://library.oapen.org/bitstream/20.500.12657/33167/1/560245.pdf https://library.oapen.org/bitstream/20.500.12657/33167/1/560245.pdf University of Adelaide Press 10.1017/UPO9780987073051 10.1017/UPO9780987073051 b117e61d-8fca-494f-b82a-41c4e1dc0a46 9780987073051 356 open access
spellingShingle magnesium
central nervous system
neurological disease
psychiatric disease
Magnesium
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology
Magnesium in the Central Nervous System
title Magnesium in the Central Nervous System
title_full Magnesium in the Central Nervous System
title_fullStr Magnesium in the Central Nervous System
title_full_unstemmed Magnesium in the Central Nervous System
title_short Magnesium in the Central Nervous System
title_sort magnesium in the central nervous system
topic magnesium
central nervous system
neurological disease
psychiatric disease
Magnesium
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology
topic_facet magnesium
central nervous system
neurological disease
psychiatric disease
Magnesium
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology
url 560245