Genetiese bevindings in ‘n groep Afrikaners met skisofrenie
This book aims to contribute to the understanding of the genetics of schizophrenia. The emphasis is on the collaborative findings of research on this topic done in the Afrikaner founder population from South Africa over more than 20 years. The collaborative research was initiated by the Rockefeller...
में बचाया:
| मुख्य लेखक: | |
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| स्वरूप: | Online |
| भाषा: | अफ़्रीकी |
| प्रकाशित: |
AOSIS
2021
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| विषय: | |
| ऑनलाइन पहुंच: | ONIX_20200512_9781928523215_15 |
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कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!
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| _version_ | 1869521593588252672 |
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| author | Roos, Johannes |
| author_browse | Roos, Johannes |
| author_facet | Roos, Johannes |
| author_sort | Roos, Johannes |
| collection | Directory of Open Access Books |
| description | This book aims to contribute to the understanding of the genetics of schizophrenia. The emphasis is on the collaborative findings of research on this topic done in the Afrikaner founder population from South Africa over more than 20 years. The collaborative research was initiated by the Rockefeller University in New York and the Department of Psychiatry at the University of Pretoria, South Africa. Columbia University, New York, joined the collaboration at a later stage. The genetic laboratory findings elucidate some aspects of the complex nature of the etiopathogenesis of this illness. It further aims to review the clinical findings in this population. A central focus of clinical interest, is early non-psychotic deviant behaviour, prior to the onset of psychosis, in the first 10 years of these patients’ lives. It is viewed as an endophenotypic marker in schizophrenia and identifies a subtype of schizophrenia that affects age of onset of illness and long-term prognosis. Clinical research findings may help clinicians to manage these patients, and aid in predicting who is vulnerable to developing the illness. This book also reports on how the scientific findings may be communicated to patients and family members during genetic counselling. There is a constant emphasis on de-stigmatisation of schizophrenia, also among treatment professionals. The original research findings on the genetics of schizophrenia in the Afrikaner founder population over a 20-year period is reviewed and restructured, with emphasis on the clinical and possible etiopathogenic explanations of the illness. The book contributes to scholarship by unfolding genetic laboratory findings and clinical aspects of schizophrenia and how it applies to management. |
| format | Online |
| id | doab-20.500.12854ir-36021 |
| institution | Directory of Open Access Books |
| language | afr |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | AOSIS |
| publisherStr | AOSIS |
| record_format | ojs |
| spelling | doab-20.500.12854ir-360212026-05-19T08:19:22Z Genetiese bevindings in ‘n groep Afrikaners met skisofrenie Roos, Johannes Schizophrenia Afrikaner patients psychiatry genetics 22q11.2 Skisofrenie pasiënte psigiatriese VANG genetiese 22q11.2-mikroweglating thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKL Psychiatry This book aims to contribute to the understanding of the genetics of schizophrenia. The emphasis is on the collaborative findings of research on this topic done in the Afrikaner founder population from South Africa over more than 20 years. The collaborative research was initiated by the Rockefeller University in New York and the Department of Psychiatry at the University of Pretoria, South Africa. Columbia University, New York, joined the collaboration at a later stage. The genetic laboratory findings elucidate some aspects of the complex nature of the etiopathogenesis of this illness. It further aims to review the clinical findings in this population. A central focus of clinical interest, is early non-psychotic deviant behaviour, prior to the onset of psychosis, in the first 10 years of these patients’ lives. It is viewed as an endophenotypic marker in schizophrenia and identifies a subtype of schizophrenia that affects age of onset of illness and long-term prognosis. Clinical research findings may help clinicians to manage these patients, and aid in predicting who is vulnerable to developing the illness. This book also reports on how the scientific findings may be communicated to patients and family members during genetic counselling. There is a constant emphasis on de-stigmatisation of schizophrenia, also among treatment professionals. The original research findings on the genetics of schizophrenia in the Afrikaner founder population over a 20-year period is reviewed and restructured, with emphasis on the clinical and possible etiopathogenic explanations of the illness. The book contributes to scholarship by unfolding genetic laboratory findings and clinical aspects of schizophrenia and how it applies to management. 2021-02-10T14:31:53Z 2021-02-10T14:31:53Z 2020-05-12T08:01:01Z 2019 book ONIX_20200512_9781928523215_15 OCN: 1229579322 http://library.oapen.org/handle/20.500.12657/37689 9781928523192 9781928523208 https://directory.doabooks.org/handle/20.500.12854/36021 afr open access image/jpeg image/jpeg image/jpeg image/jpeg Attribution-NonCommercial-ShareAlike 4.0 International Attribution-NonCommercial-ShareAlike 4.0 International Attribution-NonCommercial-ShareAlike 4.0 International Attribution-NonCommercial-ShareAlike 4.0 International https://library.oapen.org/bitstream/20.500.12657/37689/1/978-1-928523-21-5.pdf https://library.oapen.org/bitstream/20.500.12657/37689/1/978-1-928523-21-5.pdf https://library.oapen.org/bitstream/20.500.12657/37689/1/978-1-928523-21-5.pdf https://library.oapen.org/bitstream/20.500.12657/37689/1/978-1-928523-21-5.pdf AOSIS 10.4102/aosis.2019.BK135 10.4102/aosis.2019.BK135 c47a1220-d848-4e78-88cd-74f293e3d4f4 9781928523192 9781928523208 268 Durbanville open access |
| spellingShingle | Schizophrenia Afrikaner patients psychiatry genetics 22q11.2 Skisofrenie pasiënte psigiatriese VANG genetiese 22q11.2-mikroweglating thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKL Psychiatry Roos, Johannes Genetiese bevindings in ‘n groep Afrikaners met skisofrenie |
| title | Genetiese bevindings in ‘n groep Afrikaners met skisofrenie |
| title_full | Genetiese bevindings in ‘n groep Afrikaners met skisofrenie |
| title_fullStr | Genetiese bevindings in ‘n groep Afrikaners met skisofrenie |
| title_full_unstemmed | Genetiese bevindings in ‘n groep Afrikaners met skisofrenie |
| title_short | Genetiese bevindings in ‘n groep Afrikaners met skisofrenie |
| title_sort | genetiese bevindings in n groep afrikaners met skisofrenie |
| topic | Schizophrenia Afrikaner patients psychiatry genetics 22q11.2 Skisofrenie pasiënte psigiatriese VANG genetiese 22q11.2-mikroweglating thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKL Psychiatry |
| topic_facet | Schizophrenia Afrikaner patients psychiatry genetics 22q11.2 Skisofrenie pasiënte psigiatriese VANG genetiese 22q11.2-mikroweglating thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKL Psychiatry |
| url | ONIX_20200512_9781928523215_15 |
| work_keys_str_mv | AT roosjohannes genetiesebevindingsinngroepafrikanersmetskisofrenie |