Chapter 7 Finding the global in the local
Numerous studies describe the genetic make-up of populations living outside Europe and North America. Many of these tackle human genetic variation with the explicit aim of identifying gene variants of medical significance for the populations studied. However, the chapter points to rather different m...
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Manchester University Press
2021
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| Առցանց հասանելիություն: | https://library.oapen.org/handle/20.500.12657/42725 |
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| _version_ | 1869530556419538944 |
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| author | Sturdy, Steve |
| author_browse | Sturdy, Steve |
| author_facet | Sturdy, Steve |
| author_sort | Sturdy, Steve |
| collection | Directory of Open Access Books |
| description | Numerous studies describe the genetic make-up of populations living outside Europe and North America. Many of these tackle human genetic variation with the explicit aim of identifying gene variants of medical significance for the populations studied. However, the chapter points to rather different motivations, showing how recent studies documenting the genetic constitution of non-Western populations have grown out of, and serve the purposes of, efforts to identify genetic factors which influence the health of populations in Europe and North America. Analysing the past thirty-five years of medical research literature, the chapter shows how, in this context, efforts to identify genetic variants of possible significance for disease aetiology have shifted to include large-scale association studies in populations rather than families. It discusses how research with local concerns must nonetheless take into account the global distribution of genes and genotypes, thus making studies of the genetic causes of disease, wherever conducted, increasingly global in their purview. The chapter also argues that this recent knowledge of human population genomics has developed in a way which reinscribes ideas of racial difference into biomedical understanding of human populations, and creates tools for excluding supposedly non-Western populations from research oriented towards the concerns of Western institutions. |
| format | Online |
| id | doab-20.500.12854ir-38089 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Manchester University Press |
| publisherStr | Manchester University Press |
| record_format | ojs |
| spelling | doab-20.500.12854ir-380892025-02-04T04:30:56Z Chapter 7 Finding the global in the local Sturdy, Steve human genetic variation non-Western populations disease aetiology association studies population genomics thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBX History of medicine thema EDItEUR::P Mathematics and Science thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations::JPSN International institutions Numerous studies describe the genetic make-up of populations living outside Europe and North America. Many of these tackle human genetic variation with the explicit aim of identifying gene variants of medical significance for the populations studied. However, the chapter points to rather different motivations, showing how recent studies documenting the genetic constitution of non-Western populations have grown out of, and serve the purposes of, efforts to identify genetic factors which influence the health of populations in Europe and North America. Analysing the past thirty-five years of medical research literature, the chapter shows how, in this context, efforts to identify genetic variants of possible significance for disease aetiology have shifted to include large-scale association studies in populations rather than families. It discusses how research with local concerns must nonetheless take into account the global distribution of genes and genotypes, thus making studies of the genetic causes of disease, wherever conducted, increasingly global in their purview. The chapter also argues that this recent knowledge of human population genomics has developed in a way which reinscribes ideas of racial difference into biomedical understanding of human populations, and creates tools for excluding supposedly non-Western populations from research oriented towards the concerns of Western institutions. 2021-02-10T14:51:56Z 2021-02-10T14:51:56Z 2020-10-28T09:24:03Z 2020 chapter https://library.oapen.org/handle/20.500.12657/42725 https://directory.doabooks.org/handle/20.500.12854/38089 eng Social Histories of Medicine open access image/jpeg image/jpeg Attribution-NonCommercial-NoDerivatives 4.0 International Attribution-NonCommercial-NoDerivatives 4.0 International https://library.oapen.org/bitstream/20.500.12657/42725/1/9781526149688_ch7.pdf https://library.oapen.org/bitstream/20.500.12657/42725/1/9781526149688_ch7.pdf Manchester University Press bcb4ab08-c525-4e6c-88e5-a0cf0a175533 Global health and the new world order Wellcome Trust d859fbd3-d884-4090-a0ec-baf821c9abfd Wellcome 29 Manchester WT100597MA open access |
| spellingShingle | human genetic variation non-Western populations disease aetiology association studies population genomics thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBX History of medicine thema EDItEUR::P Mathematics and Science thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations::JPSN International institutions Sturdy, Steve Chapter 7 Finding the global in the local |
| title | Chapter 7 Finding the global in the local |
| title_full | Chapter 7 Finding the global in the local |
| title_fullStr | Chapter 7 Finding the global in the local |
| title_full_unstemmed | Chapter 7 Finding the global in the local |
| title_short | Chapter 7 Finding the global in the local |
| title_sort | chapter 7 finding the global in the local |
| topic | human genetic variation non-Western populations disease aetiology association studies population genomics thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBX History of medicine thema EDItEUR::P Mathematics and Science thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations::JPSN International institutions |
| topic_facet | human genetic variation non-Western populations disease aetiology association studies population genomics thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBX History of medicine thema EDItEUR::P Mathematics and Science thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations::JPSN International institutions |
| url | https://library.oapen.org/handle/20.500.12657/42725 |
| work_keys_str_mv | AT sturdysteve chapter7findingtheglobalinthelocal |