Adrenal Cortex: From Physiology to Disease
The adrenal gland plays essential roles in the control of body homeostasis, stress and immune responses. The adrenal cortex represents up to 90% of the gland and is specialised in the production of mineralocorticoids, glucocorticoids and adrenal androgens. This production is tightly coordinated and...
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| Format: | Online |
| Jezik: | engleski |
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Frontiers Media SA
2021
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| Online pristup: | 18306 |
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| _version_ | 1869529401142542336 |
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| author | Pierre Val Antoine Martinez |
| author_browse | Antoine Martinez Pierre Val |
| author_facet | Pierre Val Antoine Martinez |
| author_sort | Pierre Val |
| collection | Directory of Open Access Books |
| description | The adrenal gland plays essential roles in the control of body homeostasis, stress and immune responses. The adrenal cortex represents up to 90% of the gland and is specialised in the production of mineralocorticoids, glucocorticoids and adrenal androgens. This production is tightly coordinated and results from a unique zonal organisation. Although our knowledge of the molecular mechanisms controlling adrenal steroidogenesis is quite extensive, for decades, the mechanisms of adrenal cortex development, cellular homeostasis and renewal have remained elusive. The advent of new high-throughput technologies and sophisticated genetic approaches has brought tremendous progress in our understanding of how the adrenal cortex achieves and maintains its particular organisation. The aim of this Frontiers in Endocrinology Topic is to provide readers with a snapshot of our current knowledge on adrenal physiology and how deregulations of these processes result in adrenal diseases. This includes but is not limited to, basic research on adrenal development, cell lineage identification, progenitor cells, tissue renewal, control of differentiation and zonation and clinical research on the identification of disease-related genes. |
| format | Online |
| id | doab-20.500.12854ir-40168 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-401682024-03-31T13:10:08Z Adrenal Cortex: From Physiology to Disease Pierre Val Antoine Martinez R5-920 RC648-665 QH301-705.5 Q1-390 development adrenal Disease Hyperplasia Insufficiency zonation Physiology Adenoma Cancer thema EDItEUR::M Medicine and Nursing The adrenal gland plays essential roles in the control of body homeostasis, stress and immune responses. The adrenal cortex represents up to 90% of the gland and is specialised in the production of mineralocorticoids, glucocorticoids and adrenal androgens. This production is tightly coordinated and results from a unique zonal organisation. Although our knowledge of the molecular mechanisms controlling adrenal steroidogenesis is quite extensive, for decades, the mechanisms of adrenal cortex development, cellular homeostasis and renewal have remained elusive. The advent of new high-throughput technologies and sophisticated genetic approaches has brought tremendous progress in our understanding of how the adrenal cortex achieves and maintains its particular organisation. The aim of this Frontiers in Endocrinology Topic is to provide readers with a snapshot of our current knowledge on adrenal physiology and how deregulations of these processes result in adrenal diseases. This includes but is not limited to, basic research on adrenal development, cell lineage identification, progenitor cells, tissue renewal, control of differentiation and zonation and clinical research on the identification of disease-related genes. 2021-02-11T07:45:17Z 2021-02-11T07:45:17Z 2016-01-19 14:05:46 2016 book 18306 16648714 9782889199198 https://directory.doabooks.org/handle/20.500.12854/40168 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Adrenal_Cortex_From_Physiology_to_Disease/926#nogo http://journal.frontiersin.org/researchtopic/3087/adrenal-cortex-from-physiology-to-disease Frontiers Media SA 10.3389/978-2-88919-919-8 10.3389/978-2-88919-919-8 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889199198 89 open access |
| spellingShingle | R5-920 RC648-665 QH301-705.5 Q1-390 development adrenal Disease Hyperplasia Insufficiency zonation Physiology Adenoma Cancer thema EDItEUR::M Medicine and Nursing Pierre Val Antoine Martinez Adrenal Cortex: From Physiology to Disease |
| title | Adrenal Cortex: From Physiology to Disease |
| title_full | Adrenal Cortex: From Physiology to Disease |
| title_fullStr | Adrenal Cortex: From Physiology to Disease |
| title_full_unstemmed | Adrenal Cortex: From Physiology to Disease |
| title_short | Adrenal Cortex: From Physiology to Disease |
| title_sort | adrenal cortex from physiology to disease |
| topic | R5-920 RC648-665 QH301-705.5 Q1-390 development adrenal Disease Hyperplasia Insufficiency zonation Physiology Adenoma Cancer thema EDItEUR::M Medicine and Nursing |
| topic_facet | R5-920 RC648-665 QH301-705.5 Q1-390 development adrenal Disease Hyperplasia Insufficiency zonation Physiology Adenoma Cancer thema EDItEUR::M Medicine and Nursing |
| url | 18306 |
| work_keys_str_mv | AT pierreval adrenalcortexfromphysiologytodisease AT antoinemartinez adrenalcortexfromphysiologytodisease |