Advancing Systems Epidemiology in Cancer - Exploring Trajectories of Gene Expression

This book introduces systems epidemiology, which is a new scientific discipline borne by novel technologies. These have opened up the potential for studies of temporal changes in the carcinogenic process and the response of the immune system, all measured as functional genomics: gene expression, mic...

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Glavni autor: Eiliv Lund
Format: Online
Jezik:engleski
Izdano: Scandinavian University Press (Universitetsforlaget) 2021
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author Eiliv Lund
author_browse Eiliv Lund
author_facet Eiliv Lund
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description This book introduces systems epidemiology, which is a new scientific discipline borne by novel technologies. These have opened up the potential for studies of temporal changes in the carcinogenic process and the response of the immune system, all measured as functional genomics: gene expression, microRNA and methylation. Systems epidemiology is an integrated approach based on epidemiological methods with biobanks designed for studies of the trajectories or curves of functional genomics moving from before diagnosis, at diagnosis and postdiagnostic. It demands new epidemiological designs, the globolomic one, new statistical methods for description and analyses of time changes and incorporating basic knowledge from reductionist experiments and clinical outcomes including molecular biomarkers of cancer tissue and normal tissues.
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spelling doab-20.500.12854ir-403842024-03-30T23:22:01Z Advancing Systems Epidemiology in Cancer - Exploring Trajectories of Gene Expression Eiliv Lund R5-920 epidemiology Cancer thema EDItEUR::M Medicine and Nursing This book introduces systems epidemiology, which is a new scientific discipline borne by novel technologies. These have opened up the potential for studies of temporal changes in the carcinogenic process and the response of the immune system, all measured as functional genomics: gene expression, microRNA and methylation. Systems epidemiology is an integrated approach based on epidemiological methods with biobanks designed for studies of the trajectories or curves of functional genomics moving from before diagnosis, at diagnosis and postdiagnostic. It demands new epidemiological designs, the globolomic one, new statistical methods for description and analyses of time changes and incorporating basic knowledge from reductionist experiments and clinical outcomes including molecular biomarkers of cancer tissue and normal tissues. 2021-02-11T07:52:11Z 2021-02-11T07:52:11Z 2020-12-15 08:34:05 2020 book 51100 9788215041209 9788215041193 https://directory.doabooks.org/handle/20.500.12854/40384 eng image/png Attribution 4.0 International https://www.idunn.no/advancing_systems_epidemiology_in_cancer Scandinavian University Press (Universitetsforlaget) 10.18261/9788215041193-2020 10.18261/9788215041193-2020 85e3f3b2-1b54-434a-a3b6-6147724464f4 9788215041209 9788215041193 187 open access
spellingShingle R5-920
epidemiology
Cancer
thema EDItEUR::M Medicine and Nursing
Eiliv Lund
Advancing Systems Epidemiology in Cancer - Exploring Trajectories of Gene Expression
title Advancing Systems Epidemiology in Cancer - Exploring Trajectories of Gene Expression
title_full Advancing Systems Epidemiology in Cancer - Exploring Trajectories of Gene Expression
title_fullStr Advancing Systems Epidemiology in Cancer - Exploring Trajectories of Gene Expression
title_full_unstemmed Advancing Systems Epidemiology in Cancer - Exploring Trajectories of Gene Expression
title_short Advancing Systems Epidemiology in Cancer - Exploring Trajectories of Gene Expression
title_sort advancing systems epidemiology in cancer exploring trajectories of gene expression
topic R5-920
epidemiology
Cancer
thema EDItEUR::M Medicine and Nursing
topic_facet R5-920
epidemiology
Cancer
thema EDItEUR::M Medicine and Nursing
url 51100
work_keys_str_mv AT eilivlund advancingsystemsepidemiologyincancerexploringtrajectoriesofgeneexpression