Animal allergens: Common protein characteristics featuring their allergenicity
Among the many molecules present in our environment, some have the property to induce allergic sensitization and IgE-mediated reactions. The analysis of known major animal allergens has shown that most belong to single protein families: lipocalins and serum albumins for inhalant allergens, EF-hand p...
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| Formato: | Online |
| Idioma: | inglês |
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Frontiers Media SA
2021
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| Acesso em linha: | 19527 |
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| _version_ | 1869527329247592448 |
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| author | Christiane Hilger Annette Kuehn |
| author_browse | Annette Kuehn Christiane Hilger |
| author_facet | Christiane Hilger Annette Kuehn |
| author_sort | Christiane Hilger |
| collection | Directory of Open Access Books |
| description | Among the many molecules present in our environment, some have the property to induce allergic sensitization and IgE-mediated reactions. The analysis of known major animal allergens has shown that most belong to single protein families: lipocalins and serum albumins for inhalant allergens, EF-hand proteins, tropomyosins and caseins for the digestive allergens. The finding that allergens are often clustered in large families may be related to the fact that common structural, biochemical or functional features contribute to their allergenicity, in addition to external adjuvant factors. Currently, there is no curative treatment for animal allergy available. In order to lower allergic reactions to respiratory allergens in daily life and to food allergens upon accidental exposure, it is important to desensitize concerned patients. Tolerance induction by allergen-specific immunotherapy is in the current focus of an ambitious research. This Research Topic aims to provide a comprehensive view of the basic and recent insights on the allergenicity of animal allergens in view of their structural and functional aspects as well as allergen-specific immunotherapy. |
| format | Online |
| id | doab-20.500.12854ir-40880 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-408802024-03-31T13:09:52Z Animal allergens: Common protein characteristics featuring their allergenicity Christiane Hilger Annette Kuehn R5-920 RC581-607 allergen exposure isoallergens immune response Immunotherapy biological function allergy cross-reactivity Allergenicity Animal allergen thema EDItEUR::M Medicine and Nursing Among the many molecules present in our environment, some have the property to induce allergic sensitization and IgE-mediated reactions. The analysis of known major animal allergens has shown that most belong to single protein families: lipocalins and serum albumins for inhalant allergens, EF-hand proteins, tropomyosins and caseins for the digestive allergens. The finding that allergens are often clustered in large families may be related to the fact that common structural, biochemical or functional features contribute to their allergenicity, in addition to external adjuvant factors. Currently, there is no curative treatment for animal allergy available. In order to lower allergic reactions to respiratory allergens in daily life and to food allergens upon accidental exposure, it is important to desensitize concerned patients. Tolerance induction by allergen-specific immunotherapy is in the current focus of an ambitious research. This Research Topic aims to provide a comprehensive view of the basic and recent insights on the allergenicity of animal allergens in view of their structural and functional aspects as well as allergen-specific immunotherapy. 2021-02-11T08:12:39Z 2021-02-11T08:12:39Z 2016-08-16 10:34:25 2015 book 19527 16648714 9782889196203 https://directory.doabooks.org/handle/20.500.12854/40880 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Animal_Allergens_Common_Protein_Characteristics_Featuring_their_Allergenicity/635#nogo http://journal.frontiersin.org/researchtopic/1211/animal-allergens-common-protein-characteristics-featuring-their-allergenicity Frontiers Media SA 10.3389/978-2-88919-620-3 10.3389/978-2-88919-620-3 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889196203 88 open access |
| spellingShingle | R5-920 RC581-607 allergen exposure isoallergens immune response Immunotherapy biological function allergy cross-reactivity Allergenicity Animal allergen thema EDItEUR::M Medicine and Nursing Christiane Hilger Annette Kuehn Animal allergens: Common protein characteristics featuring their allergenicity |
| title | Animal allergens: Common protein characteristics featuring their allergenicity |
| title_full | Animal allergens: Common protein characteristics featuring their allergenicity |
| title_fullStr | Animal allergens: Common protein characteristics featuring their allergenicity |
| title_full_unstemmed | Animal allergens: Common protein characteristics featuring their allergenicity |
| title_short | Animal allergens: Common protein characteristics featuring their allergenicity |
| title_sort | animal allergens common protein characteristics featuring their allergenicity |
| topic | R5-920 RC581-607 allergen exposure isoallergens immune response Immunotherapy biological function allergy cross-reactivity Allergenicity Animal allergen thema EDItEUR::M Medicine and Nursing |
| topic_facet | R5-920 RC581-607 allergen exposure isoallergens immune response Immunotherapy biological function allergy cross-reactivity Allergenicity Animal allergen thema EDItEUR::M Medicine and Nursing |
| url | 19527 |
| work_keys_str_mv | AT christianehilger animalallergenscommonproteincharacteristicsfeaturingtheirallergenicity AT annettekuehn animalallergenscommonproteincharacteristicsfeaturingtheirallergenicity |