Beyond the conventional Renin Angiotensin System

It is well known that the activation of the circulating renin angiotensin system is involved in cardiovascular pathology including hypertension, heart failure and is responsible for important organic changes induced by diabetes. Evidence is now available that independently of the classical system, t...

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Main Author: Walmor De Mello
Format: Online
Language:English
Published: Frontiers Media SA 2021
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Online Access:18666
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author Walmor De Mello
author_browse Walmor De Mello
author_facet Walmor De Mello
author_sort Walmor De Mello
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description It is well known that the activation of the circulating renin angiotensin system is involved in cardiovascular pathology including hypertension, heart failure and is responsible for important organic changes induced by diabetes. Evidence is now available that independently of the classical system, there are local renin angiotensin systems in different organs including the heart, circulatory vessels, kidney and probably brain and that components of these local systems participate in important aspects of physiology and pathology. Of particular interest is the presence of an intracellular component-the so called intracrine renin angiotensin system, which seems related to regulation of several cellular functions. A discussion of the different aspects of this important topic is of relevance to cell biology, endocrinology, physiology and pathology and justify a comprehensive presentation to the scientific community organized by experts in their respective fields.
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spelling doab-20.500.12854ir-420252022-01-31T23:39:39Z Beyond the conventional Renin Angiotensin System Walmor De Mello RC648-665 R5-920 QH301-705.5 Q1-390 renin It is well known that the activation of the circulating renin angiotensin system is involved in cardiovascular pathology including hypertension, heart failure and is responsible for important organic changes induced by diabetes. Evidence is now available that independently of the classical system, there are local renin angiotensin systems in different organs including the heart, circulatory vessels, kidney and probably brain and that components of these local systems participate in important aspects of physiology and pathology. Of particular interest is the presence of an intracellular component-the so called intracrine renin angiotensin system, which seems related to regulation of several cellular functions. A discussion of the different aspects of this important topic is of relevance to cell biology, endocrinology, physiology and pathology and justify a comprehensive presentation to the scientific community organized by experts in their respective fields. 2021-02-11T08:59:58Z 2021-02-11T08:59:58Z 2016-03-10 08:14:32 2014 book 18666 16648714 9782889193349 https://directory.doabooks.org/handle/20.500.12854/42025 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Beyond_the_conventional_Renin_Angiotensin_System/366 http://journal.frontiersin.org/researchtopic/1511/beyond-the-conventional-renin-angiotensin-system Frontiers Media SA 10.3389/978-2-88919-334-9 10.3389/978-2-88919-334-9 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889193349 87 open access
spellingShingle RC648-665
R5-920
QH301-705.5
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renin
Walmor De Mello
Beyond the conventional Renin Angiotensin System
title Beyond the conventional Renin Angiotensin System
title_full Beyond the conventional Renin Angiotensin System
title_fullStr Beyond the conventional Renin Angiotensin System
title_full_unstemmed Beyond the conventional Renin Angiotensin System
title_short Beyond the conventional Renin Angiotensin System
title_sort beyond the conventional renin angiotensin system
topic RC648-665
R5-920
QH301-705.5
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renin
topic_facet RC648-665
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renin
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