Biology of Brain Disorders

Brain disorders, including neurological and neuropsychiatric conditions, represent a challenge for public health systems and society at large. The limited knowledge of their biology hampers the development of diagnostic tools and effective therapeutics. A clear understanding of the mechanisms that u...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Andrew Harkin, Daniela Tropea
Format: Online
Jezik:angleščina
Izdano: Frontiers Media SA 2021
Teme:
Online dostop:29613
Oznake: Označite
Brez oznak, prvi označite!
_version_ 1869514278144311296
author Andrew Harkin
Daniela Tropea
author_browse Andrew Harkin
Daniela Tropea
author_facet Andrew Harkin
Daniela Tropea
author_sort Andrew Harkin
collection Directory of Open Access Books
description Brain disorders, including neurological and neuropsychiatric conditions, represent a challenge for public health systems and society at large. The limited knowledge of their biology hampers the development of diagnostic tools and effective therapeutics. A clear understanding of the mechanisms that underlie the onset and progression of brain disorders is required in order to identify new avenues for therapeutic intervention.Overlapping genetic risk factors across different brain disorders suggest common linkages and pathophysiological mechanisms that underlie brain disorders. Methodological and technological advances are leading to new insights that go beyond traditional hypotheses. Taking account of underlying molecular, cellular and systems biology underlying brain function will play an important role in the classification of brain disorders in future.In this Research Topic, the latest advances in our understanding of biological mechanisms across different brain disorders are presented. The areas covered include developments in neurogenetics, epigenetics, plasticity, glial cell biology, neuroimmune interactions and new technologies associated with the study of brain function. Examples of how understanding of biological mechanisms are translating into research strategies that aim to advance diagnoses and treatment of brain disorders are discussed.
format Online
id doab-20.500.12854ir-42239
institution Directory of Open Access Books
language eng
publishDate 2021
publishDateRange 2021
publishDateSort 2021
publisher Frontiers Media SA
publisherStr Frontiers Media SA
record_format ojs
spelling doab-20.500.12854ir-422392024-03-30T23:21:36Z Biology of Brain Disorders Andrew Harkin Daniela Tropea R5-920 RC346-429 RC321-571 QP1-981 Q1-390 Brain Neurons neuropsychiatric Ageing neurodegeneration thema EDItEUR::M Medicine and Nursing Brain disorders, including neurological and neuropsychiatric conditions, represent a challenge for public health systems and society at large. The limited knowledge of their biology hampers the development of diagnostic tools and effective therapeutics. A clear understanding of the mechanisms that underlie the onset and progression of brain disorders is required in order to identify new avenues for therapeutic intervention.Overlapping genetic risk factors across different brain disorders suggest common linkages and pathophysiological mechanisms that underlie brain disorders. Methodological and technological advances are leading to new insights that go beyond traditional hypotheses. Taking account of underlying molecular, cellular and systems biology underlying brain function will play an important role in the classification of brain disorders in future.In this Research Topic, the latest advances in our understanding of biological mechanisms across different brain disorders are presented. The areas covered include developments in neurogenetics, epigenetics, plasticity, glial cell biology, neuroimmune interactions and new technologies associated with the study of brain function. Examples of how understanding of biological mechanisms are translating into research strategies that aim to advance diagnoses and treatment of brain disorders are discussed. 2021-02-11T09:09:28Z 2021-02-11T09:09:28Z 2018-11-16 17:17:57 2018 book 29613 16648714 9782889453801 https://directory.doabooks.org/handle/20.500.12854/42239 eng Frontiers Research Topics image/jpeg Attribution 4.0 International https://www.frontiersin.org/research-topics/4860/biology-of-brain-disorders Frontiers Media SA 10.3389/978-2-88945-380-1 10.3389/978-2-88945-380-1 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889453801 586 open access
spellingShingle R5-920
RC346-429
RC321-571
QP1-981
Q1-390
Brain
Neurons
neuropsychiatric
Ageing
neurodegeneration
thema EDItEUR::M Medicine and Nursing
Andrew Harkin
Daniela Tropea
Biology of Brain Disorders
title Biology of Brain Disorders
title_full Biology of Brain Disorders
title_fullStr Biology of Brain Disorders
title_full_unstemmed Biology of Brain Disorders
title_short Biology of Brain Disorders
title_sort biology of brain disorders
topic R5-920
RC346-429
RC321-571
QP1-981
Q1-390
Brain
Neurons
neuropsychiatric
Ageing
neurodegeneration
thema EDItEUR::M Medicine and Nursing
topic_facet R5-920
RC346-429
RC321-571
QP1-981
Q1-390
Brain
Neurons
neuropsychiatric
Ageing
neurodegeneration
thema EDItEUR::M Medicine and Nursing
url 29613
work_keys_str_mv AT andrewharkin biologyofbraindisorders
AT danielatropea biologyofbraindisorders