Bone Marrow T Cells at the Center Stage in Immunological Memory
Increasing evidence supports the notion that bone marrow (BM) represents a relevant player in T cell responses, particularly in its role as a specialized organ for long-term memory. Memory T cells are enriched in the BM over long times after priming, and can be recruited to the periphery upon antige...
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| Formatua: | Online |
| Hizkuntza: | ingelesa |
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Frontiers Media SA
2021
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| Sarrera elektronikoa: | 22944 |
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| _version_ | 1869531029311586304 |
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| author | Francesca Di Rosa Tania H. Watts |
| author_browse | Francesca Di Rosa Tania H. Watts |
| author_facet | Francesca Di Rosa Tania H. Watts |
| author_sort | Francesca Di Rosa |
| collection | Directory of Open Access Books |
| description | Increasing evidence supports the notion that bone marrow (BM) represents a relevant player in T cell responses, particularly in its role as a specialized organ for long-term memory. Memory T cells are enriched in the BM over long times after priming, and can be recruited to the periphery upon antigenic challenge. The articles in this research topic include discussions of whether these T cells are passing-through or truly resident, as well as a debate on the extent of proliferation of BM memory T cells. Original research articles in this collection include an analysis of the number of memory T cells found in different bones as well as effects of B cell depletion on T cell memory in the BM. T cells in the BM can influence a number of processes, from bone remodeling, control of cancer, to effects on hemopoiesis or Graft versus Host Disease (GVHD). This research topic contains several contributions to these topics including discussions on how to translate BM T cell knowledge into medicine. |
| format | Online |
| id | doab-20.500.12854ir-42362 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-423622024-03-31T13:10:18Z Bone Marrow T Cells at the Center Stage in Immunological Memory Francesca Di Rosa Tania H. Watts R5-920 RC581-607 Homing Cytokines niches Memory Homeostasis T cells Bone Marrow osteoimmunology Cancer graft versus host disease thema EDItEUR::M Medicine and Nursing Increasing evidence supports the notion that bone marrow (BM) represents a relevant player in T cell responses, particularly in its role as a specialized organ for long-term memory. Memory T cells are enriched in the BM over long times after priming, and can be recruited to the periphery upon antigenic challenge. The articles in this research topic include discussions of whether these T cells are passing-through or truly resident, as well as a debate on the extent of proliferation of BM memory T cells. Original research articles in this collection include an analysis of the number of memory T cells found in different bones as well as effects of B cell depletion on T cell memory in the BM. T cells in the BM can influence a number of processes, from bone remodeling, control of cancer, to effects on hemopoiesis or Graft versus Host Disease (GVHD). This research topic contains several contributions to these topics including discussions on how to translate BM T cell knowledge into medicine. 2021-02-11T09:14:15Z 2021-02-11T09:14:15Z 2017-07-06 13:27:36 2017 book 22944 16648714 9782889450930 https://directory.doabooks.org/handle/20.500.12854/42362 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Bone_Marrow_T_Cells_at_the_Center_Stage_in_Immunological_Memory/1114#nogo http://journal.frontiersin.org/researchtopic/3265/bone-marrow-t-cells-at-the-center-stage-in-immunological-memory Frontiers Media SA 10.3389/978-2-88945-093-0 10.3389/978-2-88945-093-0 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889450930 84 open access |
| spellingShingle | R5-920 RC581-607 Homing Cytokines niches Memory Homeostasis T cells Bone Marrow osteoimmunology Cancer graft versus host disease thema EDItEUR::M Medicine and Nursing Francesca Di Rosa Tania H. Watts Bone Marrow T Cells at the Center Stage in Immunological Memory |
| title | Bone Marrow T Cells at the Center Stage in Immunological Memory |
| title_full | Bone Marrow T Cells at the Center Stage in Immunological Memory |
| title_fullStr | Bone Marrow T Cells at the Center Stage in Immunological Memory |
| title_full_unstemmed | Bone Marrow T Cells at the Center Stage in Immunological Memory |
| title_short | Bone Marrow T Cells at the Center Stage in Immunological Memory |
| title_sort | bone marrow t cells at the center stage in immunological memory |
| topic | R5-920 RC581-607 Homing Cytokines niches Memory Homeostasis T cells Bone Marrow osteoimmunology Cancer graft versus host disease thema EDItEUR::M Medicine and Nursing |
| topic_facet | R5-920 RC581-607 Homing Cytokines niches Memory Homeostasis T cells Bone Marrow osteoimmunology Cancer graft versus host disease thema EDItEUR::M Medicine and Nursing |
| url | 22944 |
| work_keys_str_mv | AT francescadirosa bonemarrowtcellsatthecenterstageinimmunologicalmemory AT taniahwatts bonemarrowtcellsatthecenterstageinimmunologicalmemory |