Brain-immune interactions in health and disease

Brain-immune interactions are essential to maintain health and their dysfunction contributes to diverse human diseases. Recent data show that haematopoietic processes and immune organs are under central autonomic control. Deficient regulation of inflammatory events contributes to brain diseases, whe...

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Główni autorzy: Adam Denes, Jaleel A. Miyan
Format: Online
Język:angielski
Wydane: Frontiers Media SA 2021
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Dostęp online:17812
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author Adam Denes
Jaleel A. Miyan
author_browse Adam Denes
Jaleel A. Miyan
author_facet Adam Denes
Jaleel A. Miyan
author_sort Adam Denes
collection Directory of Open Access Books
description Brain-immune interactions are essential to maintain health and their dysfunction contributes to diverse human diseases. Recent data show that haematopoietic processes and immune organs are under central autonomic control. Deficient regulation of inflammatory events contributes to brain diseases, whereas acute or chronic brain injury is linked with the development of systemic inflammatory conditions or immunosuppression. At present, common disorders with high socio-economic burden such as cancer, cardiovascular-, neuroinflammatory- and neurodegenerative diseases, asthma, allergies, autism, psychiatric conditions and sepsis are believed to be influenced, at least in part, by the dysfunction of brain-immune communication. Since the median age of the world's population is increasing rapidly, it is expected that the burden of common non-communicable diseases will further increase, which represents a huge challenge to the health care systems worldwide. Thus, there is an increasing demand to understand and treat complex diseases, many of which are age-related, and this is not possible unless the fine-tuned communication between large systems -such as the nervous and the immune system- is comprehensively understood. Although it is impossible to cover all areas of relevant research in this field, papers in this eBook give some insight to a few important aspects of brain-immune interactions and their contribution to disease. We hope that this collection could stimulate further relevant research and facilitate discussions to support the understanding of the highly complex interactions between the immune system and the brain in health and disease.
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spelling doab-20.500.12854ir-424232022-01-31T21:04:07Z Brain-immune interactions in health and disease Adam Denes Jaleel A. Miyan RC648-665 R5-920 RC321-571 Q1-390 Autoimmunity brain-immune interactions Disease regulation Brain Injury Neuropeptides Inflammation autism psychiatric disorders Asthma Brain-immune interactions are essential to maintain health and their dysfunction contributes to diverse human diseases. Recent data show that haematopoietic processes and immune organs are under central autonomic control. Deficient regulation of inflammatory events contributes to brain diseases, whereas acute or chronic brain injury is linked with the development of systemic inflammatory conditions or immunosuppression. At present, common disorders with high socio-economic burden such as cancer, cardiovascular-, neuroinflammatory- and neurodegenerative diseases, asthma, allergies, autism, psychiatric conditions and sepsis are believed to be influenced, at least in part, by the dysfunction of brain-immune communication. Since the median age of the world's population is increasing rapidly, it is expected that the burden of common non-communicable diseases will further increase, which represents a huge challenge to the health care systems worldwide. Thus, there is an increasing demand to understand and treat complex diseases, many of which are age-related, and this is not possible unless the fine-tuned communication between large systems -such as the nervous and the immune system- is comprehensively understood. Although it is impossible to cover all areas of relevant research in this field, papers in this eBook give some insight to a few important aspects of brain-immune interactions and their contribution to disease. We hope that this collection could stimulate further relevant research and facilitate discussions to support the understanding of the highly complex interactions between the immune system and the brain in health and disease. 2021-02-11T09:17:01Z 2021-02-11T09:17:01Z 2015-12-10 11:59:06 2015 book 17812 16648714 9782889195145 https://directory.doabooks.org/handle/20.500.12854/42423 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Brain-immune_interactions_in_health_and_disease/575#nogo http://journal.frontiersin.org/researchtopic/1268/brain-immune-interactions-in-health-and-disease Frontiers Media SA 10.3389/978-2-88919-514-5 10.3389/978-2-88919-514-5 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889195145 109 open access
spellingShingle RC648-665
R5-920
RC321-571
Q1-390
Autoimmunity
brain-immune interactions
Disease
regulation
Brain Injury
Neuropeptides
Inflammation
autism
psychiatric disorders
Asthma
Adam Denes
Jaleel A. Miyan
Brain-immune interactions in health and disease
title Brain-immune interactions in health and disease
title_full Brain-immune interactions in health and disease
title_fullStr Brain-immune interactions in health and disease
title_full_unstemmed Brain-immune interactions in health and disease
title_short Brain-immune interactions in health and disease
title_sort brain immune interactions in health and disease
topic RC648-665
R5-920
RC321-571
Q1-390
Autoimmunity
brain-immune interactions
Disease
regulation
Brain Injury
Neuropeptides
Inflammation
autism
psychiatric disorders
Asthma
topic_facet RC648-665
R5-920
RC321-571
Q1-390
Autoimmunity
brain-immune interactions
Disease
regulation
Brain Injury
Neuropeptides
Inflammation
autism
psychiatric disorders
Asthma
url 17812
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