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Ca2+ and Ca2+-interlocked Membrane Guanylate Cyclase Modulation

The tale of cyclic GMP has been astonishing. Having overcome an initial disbelief, cyclic GMP has risen to its present eminence as a premium cellular signal transduction messenger of not only hormonal extracellular but also of the intracellular signals. This research topic focuses on the pathways an...

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Hoofdauteurs: Rameshwar K Sharma, Teresa Duda, Clint L Makino, Wolfgang Baehr
Formaat: Online
Taal:Engels
Gepubliceerd in: Frontiers Media SA 2021
Onderwerpen:
RC321-571
Q1-390
Glaucoma
Visceral Pain
Calcium
membrane guanylate cyclase
ANF-RGC
Gene Therapy
Cyclic GMP
synaptic plasticity
trafficking
ROS-GC
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
Online toegang:17741
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Samenvatting:The tale of cyclic GMP has been astonishing. Having overcome an initial disbelief, cyclic GMP has risen to its present eminence as a premium cellular signal transduction messenger of not only hormonal extracellular but also of the intracellular signals. This research topic focuses on the pathways and functions of membrane guanylate cyclases in different tissues of the body and their interplay with intracellular sensory signals where in many cases, cyclic GMP along with Ca2+ have taken on roles as synarchic co-messengers.

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