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Carbonic Anhydrases and Metabolism

Carbonic anhydrases (CAs; EC 4.2.1.1) are metalloenzymes present in all kingdoms of life, as they equilibrate the reaction between three simple but essential chemical species: CO2, bicarbonate, and protons. Discovered more than 80 years ago, in 1933, these enzymes have been extensively investigated...

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Hoofdauteur: Supuran, Claudiu T.
Formaat: Online
Taal:Engels
Gepubliceerd in: MDPI - Multidisciplinary Digital Publishing Institute 2021
Onderwerpen:
QH301-705.5
Q1-390
antibiotic
inhibitors
glaucoma
metabolic role
inhibitor
engineered bacteria
carbonic anhydrase inhibitors
drug discovery
enzyme inhibition
V-ATPases
photosynthesis
Chlamydomonas reinhardtii
metalloenzymes
CO2 capture
bicarbonate
benzamide
hypoxia
antibody
model alga
cancer therapeutics
CA gene family
resistance
isoforms IX and XII
cancer metabolism
MMP14
carbonic anhydrase IX
carboxylation
bacterial enzymes
antitumor agent
metabolism
activator
bacterial carbonic anhydrases
amine
amino acid
pH regulation
proton pump inhibitors
pathogens
sulfonamide
metastasis
hypoxic tumor
carbonic anhydrase
pH
carbonic anhydrases
protozoan
integrin
Entamoeba histolytica
tumors
human isoform
acidity
invasion
radiation
tumor
carbonic anhydrase XII
transporter
migration
cancer
tumor microenvironment
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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