Carboxylic Acid Production

Carboxylic acids are truly central compounds in cellular metabolism. Carbon dioxide is captured from the atmosphere through formation of carboxylic groups and is also released, in part, by decarboxylation reactions. The reactivity of the carboxylic group with amino- or hydroxyl-groups enables the fo...

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Автор: Gunnar Lidén (Ed.)
Формат: Online
Мова:Англійська
Опубліковано: MDPI - Multidisciplinary Digital Publishing Institute 2021
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Онлайн доступ:24955
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author Gunnar Lidén (Ed.)
author_browse Gunnar Lidén (Ed.)
author_facet Gunnar Lidén (Ed.)
author_sort Gunnar Lidén (Ed.)
collection Directory of Open Access Books
description Carboxylic acids are truly central compounds in cellular metabolism. Carbon dioxide is captured from the atmosphere through formation of carboxylic groups and is also released, in part, by decarboxylation reactions. The reactivity of the carboxylic group with amino- or hydroxyl-groups enables the formation of peptide and ester bonds. The functionality of the carboxylic group is also of huge importance in our industrial world for a wide range of applications. The loosely bound hydrogen provides weak acid functionality, much desired for food industry applications in preservatives and flavour compounds. Citric acid is one of our oldest industrial fermentation products. The presence of two carboxylic groups, or a combination of one carboxylic group and another functional group, make the compounds interesting building blocks for polymer production. A number of carboxylic acids, including, e.g., lactic, succinic, 3-hydroxypropionic and itaconic acids, have been identified and recognized as suitable platform chemicals for a foreseen growing carbohydrate based economy. Economic margins are, however, tight when competing with petroleum based production, and production strains, fermentation technology and—not least—downstream processing, all need to be improved to enable viable commercial production. This Special issue will cover current developments within this exciting field. Topics will include: Fermentation physiology of natural carboxylic acid producers; screening and isolation of novel producers; metabolic engineering for improving intrinsic carboxylic acid production; metabolic engineering for expanding product range to non-endogenous carboxylic acids; production from lignocellulosic derived sugars or by-product streams; downstream processing for recovery of carboxylic acids; bioprocess design—including continuous processes and integration. All production organisms—fungi, yeasts, bacteria—are welcome.
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spelling doab-20.500.12854ir-427082024-04-05T12:32:49Z Carboxylic Acid Production Gunnar Lidén (Ed.) QH301-705.5 bioprocess design downstream processing metabolic engineering strain evolution fermentation physiology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Carboxylic acids are truly central compounds in cellular metabolism. Carbon dioxide is captured from the atmosphere through formation of carboxylic groups and is also released, in part, by decarboxylation reactions. The reactivity of the carboxylic group with amino- or hydroxyl-groups enables the formation of peptide and ester bonds. The functionality of the carboxylic group is also of huge importance in our industrial world for a wide range of applications. The loosely bound hydrogen provides weak acid functionality, much desired for food industry applications in preservatives and flavour compounds. Citric acid is one of our oldest industrial fermentation products. The presence of two carboxylic groups, or a combination of one carboxylic group and another functional group, make the compounds interesting building blocks for polymer production. A number of carboxylic acids, including, e.g., lactic, succinic, 3-hydroxypropionic and itaconic acids, have been identified and recognized as suitable platform chemicals for a foreseen growing carbohydrate based economy. Economic margins are, however, tight when competing with petroleum based production, and production strains, fermentation technology and—not least—downstream processing, all need to be improved to enable viable commercial production. This Special issue will cover current developments within this exciting field. Topics will include: Fermentation physiology of natural carboxylic acid producers; screening and isolation of novel producers; metabolic engineering for improving intrinsic carboxylic acid production; metabolic engineering for expanding product range to non-endogenous carboxylic acids; production from lignocellulosic derived sugars or by-product streams; downstream processing for recovery of carboxylic acids; bioprocess design—including continuous processes and integration. All production organisms—fungi, yeasts, bacteria—are welcome. 2021-02-11T09:31:07Z 2021-02-11T09:31:07Z 2018-01-04 15:30:04 2018 book 24955 9783038425533 9783038425526 https://directory.doabooks.org/handle/20.500.12854/42708 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International http://www.mdpi.com/books/pdfview/book/390 http://www.mdpi.com/books/pdfview/book/390 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03842-553-3 10.3390/books978-3-03842-553-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038425533 9783038425526 174 open access
spellingShingle QH301-705.5
bioprocess design
downstream processing
metabolic engineering
strain evolution
fermentation physiology
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Gunnar Lidén (Ed.)
Carboxylic Acid Production
title Carboxylic Acid Production
title_full Carboxylic Acid Production
title_fullStr Carboxylic Acid Production
title_full_unstemmed Carboxylic Acid Production
title_short Carboxylic Acid Production
title_sort carboxylic acid production
topic QH301-705.5
bioprocess design
downstream processing
metabolic engineering
strain evolution
fermentation physiology
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet QH301-705.5
bioprocess design
downstream processing
metabolic engineering
strain evolution
fermentation physiology
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url 24955
work_keys_str_mv AT gunnarlidened carboxylicacidproduction