Cardiovascular Toxicities of Breast Cancer Treatment: Emerging Issues in Cardio-Oncology

Cancer and cardiovascular disease (CVD) are the two most common causes of mortality and morbidity worldwide. The incidence of both cancer and cardiovascular disease increases with age. With increased life expectancy, the burden of both these diseases will increase substantially in coming years. Pati...

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Κύριοι συγγραφείς: Sharad Goyal, Bruce George Haffty
Μορφή: Online
Γλώσσα:Αγγλικά
Έκδοση: Frontiers Media SA 2021
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Διαθέσιμο Online:20283
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author Sharad Goyal
Bruce George Haffty
author_browse Bruce George Haffty
Sharad Goyal
author_facet Sharad Goyal
Bruce George Haffty
author_sort Sharad Goyal
collection Directory of Open Access Books
description Cancer and cardiovascular disease (CVD) are the two most common causes of mortality and morbidity worldwide. The incidence of both cancer and cardiovascular disease increases with age. With increased life expectancy, the burden of both these diseases will increase substantially in coming years. Patients with CVD share multiple common risk factors and lifestyle behaviors in addition to frequently suffering from multiple comorbid conditions. Tobacco use, hypertension, high cholesterol, diabetes, physical inactivity, and poor nutrition are all established risk factors of heart disease. Patients with diseases such as breast cancer may develop CVD from treatment, such as use of chemotherapy and RT. Effects on the heart are a potentially significant and serious clinical problem in radiation therapy treatment of breast cancer. Over the course of the past 50 years, there have been great advances in the delivery of RT due to the development of new techniques, beam energy, improvement in imaging modalities, and development of image registration strategies. It is hypothesized that cardiac damage from RT is correlated to the dose absorbed by the heart and differs between left- and right-breast radiotherapy. The damage to cardiac micro- and macro-vasculature is the pathophysiological cause of RT-related heart disease. Given the growing clinical relevance of cardio-oncology, this Frontiers in Oncology Research Topic provides a venue for disseminating focused reviews and cutting edge research in this quickly growing field. We encourage submission of original papers and reviews dealing with cardiac toxicity after breast cancer treatment, motion management to reduce cardiac exposure, imaging to evaluate potential cardiac toxicities and primary prevention of cardiac disease in the breast cancer patient.
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spelling doab-20.500.12854ir-427172024-03-30T23:21:58Z Cardiovascular Toxicities of Breast Cancer Treatment: Emerging Issues in Cardio-Oncology Sharad Goyal Bruce George Haffty R5-920 RC254-282 cardiac toxicity onco-cardiology biomarkers radiation therapy Cardio-oncology breast cancer Cardiac MRI chemotherapy Cardiac dose thema EDItEUR::M Medicine and Nursing Cancer and cardiovascular disease (CVD) are the two most common causes of mortality and morbidity worldwide. The incidence of both cancer and cardiovascular disease increases with age. With increased life expectancy, the burden of both these diseases will increase substantially in coming years. Patients with CVD share multiple common risk factors and lifestyle behaviors in addition to frequently suffering from multiple comorbid conditions. Tobacco use, hypertension, high cholesterol, diabetes, physical inactivity, and poor nutrition are all established risk factors of heart disease. Patients with diseases such as breast cancer may develop CVD from treatment, such as use of chemotherapy and RT. Effects on the heart are a potentially significant and serious clinical problem in radiation therapy treatment of breast cancer. Over the course of the past 50 years, there have been great advances in the delivery of RT due to the development of new techniques, beam energy, improvement in imaging modalities, and development of image registration strategies. It is hypothesized that cardiac damage from RT is correlated to the dose absorbed by the heart and differs between left- and right-breast radiotherapy. The damage to cardiac micro- and macro-vasculature is the pathophysiological cause of RT-related heart disease. Given the growing clinical relevance of cardio-oncology, this Frontiers in Oncology Research Topic provides a venue for disseminating focused reviews and cutting edge research in this quickly growing field. We encourage submission of original papers and reviews dealing with cardiac toxicity after breast cancer treatment, motion management to reduce cardiac exposure, imaging to evaluate potential cardiac toxicities and primary prevention of cardiac disease in the breast cancer patient. 2021-02-11T09:31:21Z 2021-02-11T09:31:21Z 2017-02-03 17:04:57 2016 book 20283 16648714 9782889195695 https://directory.doabooks.org/handle/20.500.12854/42717 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Cardiovascular_Toxicities_of_Breast_Cancer_Treatment_Emerging_Issues_in_Cardio-Oncology/876#nogo http://journal.frontiersin.org/researchtopic/2399/cardiovascular-toxicities-of-breast-cancer-treatment-emerging-issues-in-cardio-oncology Frontiers Media SA 10.3389/978-2-88919-569-5 10.3389/978-2-88919-569-5 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889195695 83 open access
spellingShingle R5-920
RC254-282
cardiac toxicity
onco-cardiology
biomarkers
radiation therapy
Cardio-oncology
breast cancer
Cardiac MRI
chemotherapy
Cardiac dose
thema EDItEUR::M Medicine and Nursing
Sharad Goyal
Bruce George Haffty
Cardiovascular Toxicities of Breast Cancer Treatment: Emerging Issues in Cardio-Oncology
title Cardiovascular Toxicities of Breast Cancer Treatment: Emerging Issues in Cardio-Oncology
title_full Cardiovascular Toxicities of Breast Cancer Treatment: Emerging Issues in Cardio-Oncology
title_fullStr Cardiovascular Toxicities of Breast Cancer Treatment: Emerging Issues in Cardio-Oncology
title_full_unstemmed Cardiovascular Toxicities of Breast Cancer Treatment: Emerging Issues in Cardio-Oncology
title_short Cardiovascular Toxicities of Breast Cancer Treatment: Emerging Issues in Cardio-Oncology
title_sort cardiovascular toxicities of breast cancer treatment emerging issues in cardio oncology
topic R5-920
RC254-282
cardiac toxicity
onco-cardiology
biomarkers
radiation therapy
Cardio-oncology
breast cancer
Cardiac MRI
chemotherapy
Cardiac dose
thema EDItEUR::M Medicine and Nursing
topic_facet R5-920
RC254-282
cardiac toxicity
onco-cardiology
biomarkers
radiation therapy
Cardio-oncology
breast cancer
Cardiac MRI
chemotherapy
Cardiac dose
thema EDItEUR::M Medicine and Nursing
url 20283
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