Chimica farmaceutica: farmaci sistemici: Lezioni del prof. Ettore Novellino

For thousands of years, pharmacological knowledge coming from natural remedies, has been handed down from generation to generation, without any awareness of the ways in which preparations are made to face diseases. The advent of pharmaceutical chemistry and of the modern drug industry turned that la...

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Principais autores: Ilario Sepe, Mariapaola Camera, Roberto Colonna, Ettore Novellino, Francesca Aiardo Esposito
Formato: Online
Publicado em: FedOA - Federico II University Press 2021
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Acesso em linha:26973
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author Ilario Sepe
Mariapaola Camera
Roberto Colonna
Ettore Novellino
Francesca Aiardo Esposito
author_browse Ettore Novellino
Francesca Aiardo Esposito
Ilario Sepe
Mariapaola Camera
Roberto Colonna
author_facet Ilario Sepe
Mariapaola Camera
Roberto Colonna
Ettore Novellino
Francesca Aiardo Esposito
author_sort Ilario Sepe
collection Directory of Open Access Books
description For thousands of years, pharmacological knowledge coming from natural remedies, has been handed down from generation to generation, without any awareness of the ways in which preparations are made to face diseases. The advent of pharmaceutical chemistry and of the modern drug industry turned that lack of awareness into a scientific knowledge that changed the destiny of the human race. The twenty-eight chapters of this book, are taken from the lectures held by Professor Ettore Novellino every year in his course “Pharmaceutical Chemistry and Toxicology 2”. The first chapters address the basic notions of drugs, homeostasis, pharmacopoeia, and receptor; then, the different pharmaceutical classes are introduced by analyzing their pharmacological and chemical aspects. In particular, the structural study of the interaction between drugs and receptors or biological enzymes gives the fundamentals to connect the chemical and stereochemical properties of a compound family, with the biological activity, a correlation better known as Quantitative Structure-Activity Relationship (QSAR). Several examples of the synthesis of some of the most historically renown drugs, provided at the end of each chapter, integrate the book.
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institution Directory of Open Access Books
publishDate 2021
publishDateRange 2021
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publisher FedOA - Federico II University Press
publisherStr FedOA - Federico II University Press
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spelling doab-20.500.12854ir-431312024-04-01T14:15:04Z Chimica farmaceutica: farmaci sistemici: Lezioni del prof. Ettore Novellino Ilario Sepe Mariapaola Camera Roberto Colonna Ettore Novellino Francesca Aiardo Esposito RM1-950 Metabotropic receptor Pharmaceutical Chemistry Quantitative Structure-Activity Relationship thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology For thousands of years, pharmacological knowledge coming from natural remedies, has been handed down from generation to generation, without any awareness of the ways in which preparations are made to face diseases. The advent of pharmaceutical chemistry and of the modern drug industry turned that lack of awareness into a scientific knowledge that changed the destiny of the human race. The twenty-eight chapters of this book, are taken from the lectures held by Professor Ettore Novellino every year in his course “Pharmaceutical Chemistry and Toxicology 2”. The first chapters address the basic notions of drugs, homeostasis, pharmacopoeia, and receptor; then, the different pharmaceutical classes are introduced by analyzing their pharmacological and chemical aspects. In particular, the structural study of the interaction between drugs and receptors or biological enzymes gives the fundamentals to connect the chemical and stereochemical properties of a compound family, with the biological activity, a correlation better known as Quantitative Structure-Activity Relationship (QSAR). Several examples of the synthesis of some of the most historically renown drugs, provided at the end of each chapter, integrate the book. 2021-02-11T09:48:08Z 2021-02-11T09:48:08Z 2018-06-08 13:11:19 2017 book 26973 9788868870157 https://directory.doabooks.org/handle/20.500.12854/43131 Phármakon application/octet-stream Attribution 4.0 International http://www.fedoabooks.unina.it/index.php/fedoapress/catalog/book/60 FedOA - Federico II University Press 10.6093/978-88-6887-015-7 10.6093/978-88-6887-015-7 725b3cbf-52ac-4597-b597-c9b6ee3fc903 9788868870157 767 open access
spellingShingle RM1-950
Metabotropic receptor
Pharmaceutical Chemistry
Quantitative Structure-Activity Relationship
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology
Ilario Sepe
Mariapaola Camera
Roberto Colonna
Ettore Novellino
Francesca Aiardo Esposito
Chimica farmaceutica: farmaci sistemici: Lezioni del prof. Ettore Novellino
title Chimica farmaceutica: farmaci sistemici: Lezioni del prof. Ettore Novellino
title_full Chimica farmaceutica: farmaci sistemici: Lezioni del prof. Ettore Novellino
title_fullStr Chimica farmaceutica: farmaci sistemici: Lezioni del prof. Ettore Novellino
title_full_unstemmed Chimica farmaceutica: farmaci sistemici: Lezioni del prof. Ettore Novellino
title_short Chimica farmaceutica: farmaci sistemici: Lezioni del prof. Ettore Novellino
title_sort chimica farmaceutica farmaci sistemici lezioni del prof ettore novellino
topic RM1-950
Metabotropic receptor
Pharmaceutical Chemistry
Quantitative Structure-Activity Relationship
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology
topic_facet RM1-950
Metabotropic receptor
Pharmaceutical Chemistry
Quantitative Structure-Activity Relationship
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology
url 26973
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AT robertocolonna chimicafarmaceuticafarmacisistemicilezionidelprofettorenovellino
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