Clinical use of biomarkers in neurodegenerative disorders

The prevalence of neurodegenerative disorders is increasing dramatically and one of the major challenges today is the need of early and accurate diagnosis, the other is the need of more effective therapies -in turn the development of such therapies also requires early and accurate diagnosis-. The ma...

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Main Author: Manuel Menendez-Gonzalez
Format: Online
Language:English
Published: Frontiers Media SA 2021
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Online Access:17793
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author Manuel Menendez-Gonzalez
author_browse Manuel Menendez-Gonzalez
author_facet Manuel Menendez-Gonzalez
author_sort Manuel Menendez-Gonzalez
collection Directory of Open Access Books
description The prevalence of neurodegenerative disorders is increasing dramatically and one of the major challenges today is the need of early and accurate diagnosis, the other is the need of more effective therapies -in turn the development of such therapies also requires early and accurate diagnosis-. The main hope for an earlier and more accurate diagnosis comes from the use of biomarkers. Much research is being done trying to solve the many interrogates related to the role of biomarkers in clinical practice, including the early diagnosis, differential diagnosis and follow-up of neurodegenerative disorders. This is a field where translational research is intense enough to make this topic interesting for basic researchers and clinicians. Indeed, the amount and quality of articles received in response to the call for contributions was very good. This eBook contains a good amount of high quality articles devoted to diverse techniques across several neurodegenerative disorders from different perspectives, including original reports, reviews, methods reports and opinion letters on biochemical biomarkers in biological fluids, neuroimaging techniques and multidimensional approaches linking clinical findings with biomarkers. The disorders covered are also diverse: Alzheimer’s disease, Frontotemporal Dementia, Dementia with Lewy Bodies, Huntington’s disease, Parkinson’s disease among others. As we can learn from articles in this Research Topic, biomarkers are allowing us to expand the knowledge on the biological and anatomical basis of neurodegenerative diseases and to implement diagnostic techniques in clinical practice and clinical trials.
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spelling doab-20.500.12854ir-434052024-04-05T12:36:15Z Clinical use of biomarkers in neurodegenerative disorders Manuel Menendez-Gonzalez RC321-571 Q1-390 Neurodegenerative Diseases neurodegenerative disease Parkinson's disease MTAi biomarker Huntington's disease CSF biomarkers Frontotemporal dementia (FTD) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences The prevalence of neurodegenerative disorders is increasing dramatically and one of the major challenges today is the need of early and accurate diagnosis, the other is the need of more effective therapies -in turn the development of such therapies also requires early and accurate diagnosis-. The main hope for an earlier and more accurate diagnosis comes from the use of biomarkers. Much research is being done trying to solve the many interrogates related to the role of biomarkers in clinical practice, including the early diagnosis, differential diagnosis and follow-up of neurodegenerative disorders. This is a field where translational research is intense enough to make this topic interesting for basic researchers and clinicians. Indeed, the amount and quality of articles received in response to the call for contributions was very good. This eBook contains a good amount of high quality articles devoted to diverse techniques across several neurodegenerative disorders from different perspectives, including original reports, reviews, methods reports and opinion letters on biochemical biomarkers in biological fluids, neuroimaging techniques and multidimensional approaches linking clinical findings with biomarkers. The disorders covered are also diverse: Alzheimer’s disease, Frontotemporal Dementia, Dementia with Lewy Bodies, Huntington’s disease, Parkinson’s disease among others. As we can learn from articles in this Research Topic, biomarkers are allowing us to expand the knowledge on the biological and anatomical basis of neurodegenerative diseases and to implement diagnostic techniques in clinical practice and clinical trials. 2021-02-11T10:02:52Z 2021-02-11T10:02:52Z 2015-12-10 11:59:06 2014 book 17793 16648714 9782889194001 https://directory.doabooks.org/handle/20.500.12854/43405 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Clinical_use_of_biomarkers_for_neurodegenerative_disorders/381 http://journal.frontiersin.org/researchtopic/893/clinical-use-of-biomarkers-for-neurodegenerative-disorders Frontiers Media SA 10.3389/978-2-88919-400-1 10.3389/978-2-88919-400-1 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889194001 122 open access
spellingShingle RC321-571
Q1-390
Neurodegenerative Diseases
neurodegenerative disease
Parkinson's disease
MTAi
biomarker
Huntington's disease
CSF biomarkers
Frontotemporal dementia (FTD)
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
Manuel Menendez-Gonzalez
Clinical use of biomarkers in neurodegenerative disorders
title Clinical use of biomarkers in neurodegenerative disorders
title_full Clinical use of biomarkers in neurodegenerative disorders
title_fullStr Clinical use of biomarkers in neurodegenerative disorders
title_full_unstemmed Clinical use of biomarkers in neurodegenerative disorders
title_short Clinical use of biomarkers in neurodegenerative disorders
title_sort clinical use of biomarkers in neurodegenerative disorders
topic RC321-571
Q1-390
Neurodegenerative Diseases
neurodegenerative disease
Parkinson's disease
MTAi
biomarker
Huntington's disease
CSF biomarkers
Frontotemporal dementia (FTD)
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
topic_facet RC321-571
Q1-390
Neurodegenerative Diseases
neurodegenerative disease
Parkinson's disease
MTAi
biomarker
Huntington's disease
CSF biomarkers
Frontotemporal dementia (FTD)
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
url 17793
work_keys_str_mv AT manuelmenendezgonzalez clinicaluseofbiomarkersinneurodegenerativedisorders