The Coevolution of IDO1 and AhR in the Emergence of Regulatory T Cells in Mammals

Indoleamine 2,3-dioxygenase (IDO1) is an ancestral enzyme that, initially confined to the regulation of tryptophan availability in local tissue microenvironments, is now considered to play a wider role that extends to homeostasis and plasticity of the immune system. Thus IDO biology has implications...

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Autori principali: Ursula Grohmann, Paolo Puccetti
Natura: Online
Lingua:inglese
Pubblicazione: Frontiers Media SA 2021
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Accesso online:18849
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