Computational and Experimental Approaches in Multi-Target Pharmacology
The next frontier in pharmacology is the development of multi-target strategies in which pathological processes are controlled by pharmacologically manipulating them at many different points at once. Designing multi-target strategies will require deep understanding of the complex physiology that und...
Spremljeno u:
| Glavni autor: | |
|---|---|
| Format: | Online |
| Jezik: | engleski |
| Izdano: |
Frontiers Media SA
2021
|
| Teme: | |
| Online pristup: | 25566 |
| Oznake: |
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|
| _version_ | 1869522576713187328 |
|---|---|
| author | Thomas J. Anastasio |
| author_browse | Thomas J. Anastasio |
| author_facet | Thomas J. Anastasio |
| author_sort | Thomas J. Anastasio |
| collection | Directory of Open Access Books |
| description | The next frontier in pharmacology is the development of multi-target strategies in which pathological processes are controlled by pharmacologically manipulating them at many different points at once. Designing multi-target strategies will require deep understanding of the complex physiology that underlies pathological processes. It will also require the development of single drugs with multiple targets, or combinations of drugs with compatible pharmacokinetics that work synergistically to maximize desirable effects while minimizing unwanted side effects. This e-Book contains ten original articles, each addressing a different aspect of this challenge. Together they open new perspectives and show the way forward in the development of multi-target therapeutics. |
| format | Online |
| id | doab-20.500.12854ir-43699 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-436992024-04-01T14:14:57Z Computational and Experimental Approaches in Multi-Target Pharmacology Thomas J. Anastasio RM1-950 Q1-390 systems biology computer modeling drug repurposing synergy drug discovery drug combination high throughput screening multidrug therapeutics polypharmacy multifactorial process thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology The next frontier in pharmacology is the development of multi-target strategies in which pathological processes are controlled by pharmacologically manipulating them at many different points at once. Designing multi-target strategies will require deep understanding of the complex physiology that underlies pathological processes. It will also require the development of single drugs with multiple targets, or combinations of drugs with compatible pharmacokinetics that work synergistically to maximize desirable effects while minimizing unwanted side effects. This e-Book contains ten original articles, each addressing a different aspect of this challenge. Together they open new perspectives and show the way forward in the development of multi-target therapeutics. 2021-02-11T10:18:58Z 2021-02-11T10:18:58Z 2018-02-27 16:16:44 2017 book 25566 16648714 9782889452521 https://directory.doabooks.org/handle/20.500.12854/43699 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Computational_and_Experimental_Approaches_in_Multi-target_Pharmacology/1301 http://journal.frontiersin.org/researchtopic/3524/computational-and-experimental-approaches-in-multi-target-pharmacology Frontiers Media SA 10.3389/978-2-88945-252-1 10.3389/978-2-88945-252-1 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889452521 122 open access |
| spellingShingle | RM1-950 Q1-390 systems biology computer modeling drug repurposing synergy drug discovery drug combination high throughput screening multidrug therapeutics polypharmacy multifactorial process thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology Thomas J. Anastasio Computational and Experimental Approaches in Multi-Target Pharmacology |
| title | Computational and Experimental Approaches in Multi-Target Pharmacology |
| title_full | Computational and Experimental Approaches in Multi-Target Pharmacology |
| title_fullStr | Computational and Experimental Approaches in Multi-Target Pharmacology |
| title_full_unstemmed | Computational and Experimental Approaches in Multi-Target Pharmacology |
| title_short | Computational and Experimental Approaches in Multi-Target Pharmacology |
| title_sort | computational and experimental approaches in multi target pharmacology |
| topic | RM1-950 Q1-390 systems biology computer modeling drug repurposing synergy drug discovery drug combination high throughput screening multidrug therapeutics polypharmacy multifactorial process thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology |
| topic_facet | RM1-950 Q1-390 systems biology computer modeling drug repurposing synergy drug discovery drug combination high throughput screening multidrug therapeutics polypharmacy multifactorial process thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology |
| url | 25566 |
| work_keys_str_mv | AT thomasjanastasio computationalandexperimentalapproachesinmultitargetpharmacology |