Current Aspects of Radiopharmaceutical Chemistry
Positron emission tomography (PET) and single-photon emission computed tomography (SPECT) are in vivo molecular imaging techniques which are widely used in nuclear medicine for the diagnosis and treatment follow-up of many major diseases. They use biomolecules as probes, which are labeled with radio...
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| Format: | Online |
| Language: | English |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Online Access: | 28636 |
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| _version_ | 1869515877060182016 |
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| author | Peter Brust (Ed.) |
| author_browse | Peter Brust (Ed.) |
| author_facet | Peter Brust (Ed.) |
| author_sort | Peter Brust (Ed.) |
| collection | Directory of Open Access Books |
| description | Positron emission tomography (PET) and single-photon emission computed tomography (SPECT) are in vivo molecular imaging techniques which are widely used in nuclear medicine for the diagnosis and treatment follow-up of many major diseases. They use biomolecules as probes, which are labeled with radionuclides of short half-lives, synthesized prior to the imaging studies. These probes are called radiopharmaceuticals. Their design and development require a rather interdisciplinary process involving many different disciplines of natural and health sciences. In addition to their diagnostic and therapeutic purposes in the field of nuclear medicine, radiopharmaceuticals provide powerful tools for in vivo pharmacology during the process of pre-clinical drug development to identify new drug targets, investigate the pathophysiology of diseases, discover potential drug candidates, and evaluate the pharmacokinetics and pharmacodynamics of drugs in vivo. Furthermore, they allow molecular imaging studies in various small-animal models of disease, including genetically engineered animals. The current collection of articles provides unique examples covering all major aspects in the field. |
| format | Online |
| id | doab-20.500.12854ir-44407 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-444072024-04-05T12:38:49Z Current Aspects of Radiopharmaceutical Chemistry Peter Brust (Ed.) QD1-999 R895-920 Neuroimaging Structure-based radiotracer design Radiotracer metabolism Radiolabelling Fluorine-18 chemistry Radionuclide generators Target validation Ligand-based radiotracer design Tumor imaging Carbon-11 chemistry thema EDItEUR::P Mathematics and Science::PN Chemistry Positron emission tomography (PET) and single-photon emission computed tomography (SPECT) are in vivo molecular imaging techniques which are widely used in nuclear medicine for the diagnosis and treatment follow-up of many major diseases. They use biomolecules as probes, which are labeled with radionuclides of short half-lives, synthesized prior to the imaging studies. These probes are called radiopharmaceuticals. Their design and development require a rather interdisciplinary process involving many different disciplines of natural and health sciences. In addition to their diagnostic and therapeutic purposes in the field of nuclear medicine, radiopharmaceuticals provide powerful tools for in vivo pharmacology during the process of pre-clinical drug development to identify new drug targets, investigate the pathophysiology of diseases, discover potential drug candidates, and evaluate the pharmacokinetics and pharmacodynamics of drugs in vivo. Furthermore, they allow molecular imaging studies in various small-animal models of disease, including genetically engineered animals. The current collection of articles provides unique examples covering all major aspects in the field. 2021-02-11T10:52:58Z 2021-02-11T10:52:58Z 2018-09-19 11:46:43 2018 book 28636 9783038971627 9783038971634 https://directory.doabooks.org/handle/20.500.12854/44407 eng image/jpeg Attribution-NonCommercial-NoDerivatives 4.0 International https://play.google.com/books/publish/a/14935057684283403269#details/ISBN:9783038971627 http://www.mdpi.com/books/pdfview/book/739 http://www.mdpi.com/books/pdfview/book/739 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03897-163-4 10.3390/books978-3-03897-163-4 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038971627 9783038971634 216 open access |
| spellingShingle | QD1-999 R895-920 Neuroimaging Structure-based radiotracer design Radiotracer metabolism Radiolabelling Fluorine-18 chemistry Radionuclide generators Target validation Ligand-based radiotracer design Tumor imaging Carbon-11 chemistry thema EDItEUR::P Mathematics and Science::PN Chemistry Peter Brust (Ed.) Current Aspects of Radiopharmaceutical Chemistry |
| title | Current Aspects of Radiopharmaceutical Chemistry |
| title_full | Current Aspects of Radiopharmaceutical Chemistry |
| title_fullStr | Current Aspects of Radiopharmaceutical Chemistry |
| title_full_unstemmed | Current Aspects of Radiopharmaceutical Chemistry |
| title_short | Current Aspects of Radiopharmaceutical Chemistry |
| title_sort | current aspects of radiopharmaceutical chemistry |
| topic | QD1-999 R895-920 Neuroimaging Structure-based radiotracer design Radiotracer metabolism Radiolabelling Fluorine-18 chemistry Radionuclide generators Target validation Ligand-based radiotracer design Tumor imaging Carbon-11 chemistry thema EDItEUR::P Mathematics and Science::PN Chemistry |
| topic_facet | QD1-999 R895-920 Neuroimaging Structure-based radiotracer design Radiotracer metabolism Radiolabelling Fluorine-18 chemistry Radionuclide generators Target validation Ligand-based radiotracer design Tumor imaging Carbon-11 chemistry thema EDItEUR::P Mathematics and Science::PN Chemistry |
| url | 28636 |
| work_keys_str_mv | AT peterbrusted currentaspectsofradiopharmaceuticalchemistry |