Diagnostic, Prognostic and Predictive Biomarkers in Prostate Cancer
Prostate cancer is the most common cancer in men in the Western world. Therefore, its early diagnosis in particular, which is mainly based on serum prostate-specific antigen (PSA), has gained attention in several fields of research. New biomarkers in serum and urine have been described, for example,...
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| Формат: | Online |
| Мова: | Англійська |
| Опубліковано: |
MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Предмети: | |
| Онлайн доступ: | 25028 |
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| _version_ | 1869530748653928448 |
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| author | Carsten Stephan (Ed.) |
| author_browse | Carsten Stephan (Ed.) |
| author_facet | Carsten Stephan (Ed.) |
| author_sort | Carsten Stephan (Ed.) |
| collection | Directory of Open Access Books |
| description | Prostate cancer is the most common cancer in men in the Western world. Therefore, its early diagnosis in particular, which is mainly based on serum prostate-specific antigen (PSA), has gained attention in several fields of research. New biomarkers in serum and urine have been described, for example, the prostate health index (PHI) or urinary Prostate cancer gene 3 (PCA3), or others including several biomarker-based multivariate models. In addition to three studies and two reviews regarding PHI and other markers within this Special Issue “Diagnostic, Prognostic and Predictive Biomarkers in Prostate Cancer”, new immunoassays with the PCa-associated aberrant glycosylation of PSA (S2,3PSA) have been published. However, it is important to know not only the diagnosis, but also the prognosis or further prediction of this very common disease. Here, several new nucleic acid or protein-based tissue biomarkers have been described. Most studies in this Special Issue used tissue microarrays and immunohistochemistry. As already described for other types of cancer, individualized medicine, such as theranostics, a combination of diagnostics and therapeutics, represents a new area of interest for prostate cancer. Here, a very comprehensive review presents and discusses various important and promising kinds of nanoparticles, as well as imaging and therapy options, suitable for theranostic applications. |
| format | Online |
| id | doab-20.500.12854ir-45008 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-450082024-03-31T13:10:15Z Diagnostic, Prognostic and Predictive Biomarkers in Prostate Cancer Carsten Stephan (Ed.) R5-920 urinary biomarkers on prostate cancer serum/plasma biomarkers multivariate models prognostic factors tissue biomarkers (nuleic acid/protein-based) thema EDItEUR::M Medicine and Nursing Prostate cancer is the most common cancer in men in the Western world. Therefore, its early diagnosis in particular, which is mainly based on serum prostate-specific antigen (PSA), has gained attention in several fields of research. New biomarkers in serum and urine have been described, for example, the prostate health index (PHI) or urinary Prostate cancer gene 3 (PCA3), or others including several biomarker-based multivariate models. In addition to three studies and two reviews regarding PHI and other markers within this Special Issue “Diagnostic, Prognostic and Predictive Biomarkers in Prostate Cancer”, new immunoassays with the PCa-associated aberrant glycosylation of PSA (S2,3PSA) have been published. However, it is important to know not only the diagnosis, but also the prognosis or further prediction of this very common disease. Here, several new nucleic acid or protein-based tissue biomarkers have been described. Most studies in this Special Issue used tissue microarrays and immunohistochemistry. As already described for other types of cancer, individualized medicine, such as theranostics, a combination of diagnostics and therapeutics, represents a new area of interest for prostate cancer. Here, a very comprehensive review presents and discusses various important and promising kinds of nanoparticles, as well as imaging and therapy options, suitable for theranostic applications. 2021-02-11T11:21:45Z 2021-02-11T11:21:45Z 2018-01-10 12:43:57 2017 book 25028 9783038426332 9783038426325 https://directory.doabooks.org/handle/20.500.12854/45008 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International http://www.mdpi.com/books/pdfview/book/489 http://www.mdpi.com/books/pdfview/book/489 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03842-633-2 10.3390/books978-3-03842-633-2 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038426332 9783038426325 428 open access |
| spellingShingle | R5-920 urinary biomarkers on prostate cancer serum/plasma biomarkers multivariate models prognostic factors tissue biomarkers (nuleic acid/protein-based) thema EDItEUR::M Medicine and Nursing Carsten Stephan (Ed.) Diagnostic, Prognostic and Predictive Biomarkers in Prostate Cancer |
| title | Diagnostic, Prognostic and Predictive Biomarkers in Prostate Cancer |
| title_full | Diagnostic, Prognostic and Predictive Biomarkers in Prostate Cancer |
| title_fullStr | Diagnostic, Prognostic and Predictive Biomarkers in Prostate Cancer |
| title_full_unstemmed | Diagnostic, Prognostic and Predictive Biomarkers in Prostate Cancer |
| title_short | Diagnostic, Prognostic and Predictive Biomarkers in Prostate Cancer |
| title_sort | diagnostic prognostic and predictive biomarkers in prostate cancer |
| topic | R5-920 urinary biomarkers on prostate cancer serum/plasma biomarkers multivariate models prognostic factors tissue biomarkers (nuleic acid/protein-based) thema EDItEUR::M Medicine and Nursing |
| topic_facet | R5-920 urinary biomarkers on prostate cancer serum/plasma biomarkers multivariate models prognostic factors tissue biomarkers (nuleic acid/protein-based) thema EDItEUR::M Medicine and Nursing |
| url | 25028 |
| work_keys_str_mv | AT carstenstephaned diagnosticprognosticandpredictivebiomarkersinprostatecancer |