Dietary Bioactives and Bone Health
There is general agreement within the fields of food, nutrition, and medical sciences that an individual’s diet and lifestyle can substantially predispose one to, or protect against osteoporosis, low bone mass, and numerous other age-related bone diseases. Dietary bioactives, found diversity in a va...
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| Format: | Online |
| Langue: | anglais |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Accès en ligne: | 26576 |
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| _version_ | 1869519857502912512 |
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| author | Taylor C. Wallace (Ed.) |
| author_browse | Taylor C. Wallace (Ed.) |
| author_facet | Taylor C. Wallace (Ed.) |
| author_sort | Taylor C. Wallace (Ed.) |
| collection | Directory of Open Access Books |
| description | There is general agreement within the fields of food, nutrition, and medical sciences that an individual’s diet and lifestyle can substantially predispose one to, or protect against osteoporosis, low bone mass, and numerous other age-related bone diseases. Dietary bioactives, found diversity in a variety of foods from fruits to vegetables, herbs and spices, essential oils and beverages, have the potential to influence bone health. The NIH Office of Dietary Supplements has defined dietary bioactives as “compounds that are constituents in foods and dietary supplements, other than those needed to meet basic human nutritional needs, which are responsible for changes in health status.” These compounds are generally thought to be safe in food at normal consumption levels (e.g., polyphenols in plant foods). Dietary bioactives are currently being assessed for their properties beyond antioxidant capacity, including anti-inflammatory actions. Some compounds or classes of compounds have been reported to enhance bone formation and inhibit bone resorption through their actions on cell signaling pathways that influence osteoblast and osteoclast differentiation. Emerging scientific evidence is available, including observational studies and small clinical interventions that suggest consumption of certain dietary bioactives may have beneficial effects on bone health. Animal models have the unique advantage of feeding controlled diets for extended periods of time to assess long-term changes in bone. While bone mineral density (BMD) is the gold standard for assessing fracture risk, other factors such as bone structure, including trabecular thickness and separation, influence bone strength. Bone turnover rate is also predictive of fracture. Future research is needed to determine the types and quantities of dietary bioactives that are most effective and at what dose, as well as the mechanisms involved in modulating cellular events, in order to set precedence for larger clinical trials. |
| format | Online |
| id | doab-20.500.12854ir-45084 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-450842024-04-05T12:32:25Z Dietary Bioactives and Bone Health Taylor C. Wallace (Ed.) QH301-705.5 bioactives dietary bone osteoporosis thema EDItEUR::P Mathematics and Science::PS Biology, life sciences There is general agreement within the fields of food, nutrition, and medical sciences that an individual’s diet and lifestyle can substantially predispose one to, or protect against osteoporosis, low bone mass, and numerous other age-related bone diseases. Dietary bioactives, found diversity in a variety of foods from fruits to vegetables, herbs and spices, essential oils and beverages, have the potential to influence bone health. The NIH Office of Dietary Supplements has defined dietary bioactives as “compounds that are constituents in foods and dietary supplements, other than those needed to meet basic human nutritional needs, which are responsible for changes in health status.” These compounds are generally thought to be safe in food at normal consumption levels (e.g., polyphenols in plant foods). Dietary bioactives are currently being assessed for their properties beyond antioxidant capacity, including anti-inflammatory actions. Some compounds or classes of compounds have been reported to enhance bone formation and inhibit bone resorption through their actions on cell signaling pathways that influence osteoblast and osteoclast differentiation. Emerging scientific evidence is available, including observational studies and small clinical interventions that suggest consumption of certain dietary bioactives may have beneficial effects on bone health. Animal models have the unique advantage of feeding controlled diets for extended periods of time to assess long-term changes in bone. While bone mineral density (BMD) is the gold standard for assessing fracture risk, other factors such as bone structure, including trabecular thickness and separation, influence bone strength. Bone turnover rate is also predictive of fracture. Future research is needed to determine the types and quantities of dietary bioactives that are most effective and at what dose, as well as the mechanisms involved in modulating cellular events, in order to set precedence for larger clinical trials. 2021-02-11T11:24:46Z 2021-02-11T11:24:46Z 2018-04-20 13:26:39 2018 book 26576 9783038428466 9783038428459 https://directory.doabooks.org/handle/20.500.12854/45084 eng image/png Attribution-NonCommercial-NoDerivatives 4.0 International http://www.mdpi.com/books/pdfview/book/583 http://www.mdpi.com/books/pdfview/book/583 MDPI - Multidisciplinary Digital Publishing Institute 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038428466 9783038428459 VI, 188 open access |
| spellingShingle | QH301-705.5 bioactives dietary bone osteoporosis thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Taylor C. Wallace (Ed.) Dietary Bioactives and Bone Health |
| title | Dietary Bioactives and Bone Health |
| title_full | Dietary Bioactives and Bone Health |
| title_fullStr | Dietary Bioactives and Bone Health |
| title_full_unstemmed | Dietary Bioactives and Bone Health |
| title_short | Dietary Bioactives and Bone Health |
| title_sort | dietary bioactives and bone health |
| topic | QH301-705.5 bioactives dietary bone osteoporosis thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | QH301-705.5 bioactives dietary bone osteoporosis thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | 26576 |
| work_keys_str_mv | AT taylorcwallaceed dietarybioactivesandbonehealth |