Dinophysis Toxins: Distribution, Fate in Shellfish and Impacts
Several species of Dinophysis produce one or two groups of lipophilic toxins: okadaic acid (OA) and its derivatives; or the dinophysistoxins (DTXs) (also known as diarrhetic shellfish poisons or DSP toxins) and pectenotoxins (PTXs). DSP toxins are potent inhibitors of protein phosphatases, causing g...
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| 在線閱讀: | 42539 |
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| _version_ | 1869517914182254592 |
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| author | Blanco, Juan C. Reguera, Beatriz |
| author_browse | Blanco, Juan C. Reguera, Beatriz |
| author_facet | Blanco, Juan C. Reguera, Beatriz |
| author_sort | Blanco, Juan C. |
| collection | Directory of Open Access Books |
| description | Several species of Dinophysis produce one or two groups of lipophilic toxins: okadaic acid (OA) and its derivatives; or the dinophysistoxins (DTXs) (also known as diarrhetic shellfish poisons or DSP toxins) and pectenotoxins (PTXs). DSP toxins are potent inhibitors of protein phosphatases, causing gastrointestinal intoxication in consumers of contaminated seafood. Forty years after the identification of Dinophysis as the causative agent of DSP in Japan, contamination of filter feeding shellfish exposed to Dinophysis blooms is recognized as a problem worldwide. DSP events affect public health and cause considerable losses to the shellfish industry. Costly monitoring programs are implemented in regions with relevant shellfish production to prevent these socioeconomic impacts. Harvest closures are enforced whenever toxin levels exceed regulatory limits (RLs). Dinophysis species are kleptoplastidic dinoflagellates; they feed on ciliates (Mesodinium genus) that have previously acquired plastids from cryptophycean (genera Teleaulax, Plagioselmis, and Geminigera) nanoflagellates. The interactions of Dinophysis with different prey regulate their growth and toxin production. When Dinophysis cells are ingested by shellfish, their toxins are partially biotransformed and bioaccumulated, rendering the shellfish unsuitable for human consumption. DSP toxins may also affect shellfish metabolism. This book covers diverse aspects of the abovementioned topics—from the laboratory culture of Dinophysis and the kinetics of uptake, transformation, and depuration of DSP toxins in shellfish to Dinophysis population dynamics, the monitoring and regulation of DSP toxins, and their impact on the shellfish industry in some of the aquaculture regions that are traditionally most affected, namely, northeastern Japan, western Europe, southern Chile, and New Zealand. |
| format | Online |
| id | doab-20.500.12854ir-45199 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-451992024-03-30T23:22:13Z Dinophysis Toxins: Distribution, Fate in Shellfish and Impacts Blanco, Juan C. Reguera, Beatriz R5-920 RA1190-1270 WitOMI analysis n/a DST accumulation mussel dinophysistoxins depuration human health pectenotoxins (PTXs) cryptophytes Mesodinium dinophysis compartmentalization resistance Japanese scallop surf clam HAB monitoring toxins organic matter OMI analysis PTXs time-series Diarrhetic shellfish toxins predator-prey preferences immunity okadaic acid physical–biological interactions defense digestion Dinophysis harmful algal blooms pectenotoxin El Niño Southern Oscillation lysate suspended particulate matter (SPM) D. caudata mixotrophic cultures Mytilus galloprovincialis bivalves diarrhetic shellfish poisoning biotransformation Mesodinium cf. rubrum RNA-Seq DST esterification Mesodinium rubrum statistical analysis seasonality mass culture conditions D. acuminata-complex Argopecten purpuratus harmful algal bloom pipis (Plebidonax deltoides) DTX-2 Reloncaví Fjord pectenotoxins deep sequencing climatic anomaly Brazil qPCR high throughput sequencing DSP accumulation LC/MS/MS Protoceratium reticulatum shellfish toxicity transcriptomic response New Zealand blooms trophic transfer metabolism bacterial community kinetics marine biotoxins diarrhetic shellfish toxins bivalve shellfish Diarrhetic Shellfish Toxins (DST) diarrhetic shellfish toxins (DST) Scotland Dinophysis acuminata DSP toxins toxin accumulation Southern Annual Mode Diarrheic Shellfish Poisoning Dinophysis toxins OA marine toxins toxin vectors wild harvest Dinophysis acuta Sydney rock oyster (Saccostrea glomerata) Argopecten irradians dinophysistoxin Port Underwood aquaculture niche partitioning thema EDItEUR::M Medicine and Nursing Several species of Dinophysis produce one or two groups of lipophilic toxins: okadaic acid (OA) and its derivatives; or the dinophysistoxins (DTXs) (also known as diarrhetic shellfish poisons or DSP toxins) and pectenotoxins (PTXs). DSP toxins are potent inhibitors of protein phosphatases, causing gastrointestinal intoxication in consumers of contaminated seafood. Forty years after the identification of Dinophysis as the causative agent of DSP in Japan, contamination of filter feeding shellfish exposed to Dinophysis blooms is recognized as a problem worldwide. DSP events affect public health and cause considerable losses to the shellfish industry. Costly monitoring programs are implemented in regions with relevant shellfish production to prevent these socioeconomic impacts. Harvest closures are enforced whenever toxin levels exceed regulatory limits (RLs). Dinophysis species are kleptoplastidic dinoflagellates; they feed on ciliates (Mesodinium genus) that have previously acquired plastids from cryptophycean (genera Teleaulax, Plagioselmis, and Geminigera) nanoflagellates. The interactions of Dinophysis with different prey regulate their growth and toxin production. When Dinophysis cells are ingested by shellfish, their toxins are partially biotransformed and bioaccumulated, rendering the shellfish unsuitable for human consumption. DSP toxins may also affect shellfish metabolism. This book covers diverse aspects of the abovementioned topics—from the laboratory culture of Dinophysis and the kinetics of uptake, transformation, and depuration of DSP toxins in shellfish to Dinophysis population dynamics, the monitoring and regulation of DSP toxins, and their impact on the shellfish industry in some of the aquaculture regions that are traditionally most affected, namely, northeastern Japan, western Europe, southern Chile, and New Zealand. 2021-02-11T11:31:31Z 2021-02-11T11:31:31Z 2019-12-09 11:49:15 2019 book 42539 9783039213634 9783039213641 https://directory.doabooks.org/handle/20.500.12854/45199 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/1570 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03921-364-1 10.3390/books978-3-03921-364-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039213634 9783039213641 376 open access |
| spellingShingle | R5-920 RA1190-1270 WitOMI analysis n/a DST accumulation mussel dinophysistoxins depuration human health pectenotoxins (PTXs) cryptophytes Mesodinium dinophysis compartmentalization resistance Japanese scallop surf clam HAB monitoring toxins organic matter OMI analysis PTXs time-series Diarrhetic shellfish toxins predator-prey preferences immunity okadaic acid physical–biological interactions defense digestion Dinophysis harmful algal blooms pectenotoxin El Niño Southern Oscillation lysate suspended particulate matter (SPM) D. caudata mixotrophic cultures Mytilus galloprovincialis bivalves diarrhetic shellfish poisoning biotransformation Mesodinium cf. rubrum RNA-Seq DST esterification Mesodinium rubrum statistical analysis seasonality mass culture conditions D. acuminata-complex Argopecten purpuratus harmful algal bloom pipis (Plebidonax deltoides) DTX-2 Reloncaví Fjord pectenotoxins deep sequencing climatic anomaly Brazil qPCR high throughput sequencing DSP accumulation LC/MS/MS Protoceratium reticulatum shellfish toxicity transcriptomic response New Zealand blooms trophic transfer metabolism bacterial community kinetics marine biotoxins diarrhetic shellfish toxins bivalve shellfish Diarrhetic Shellfish Toxins (DST) diarrhetic shellfish toxins (DST) Scotland Dinophysis acuminata DSP toxins toxin accumulation Southern Annual Mode Diarrheic Shellfish Poisoning Dinophysis toxins OA marine toxins toxin vectors wild harvest Dinophysis acuta Sydney rock oyster (Saccostrea glomerata) Argopecten irradians dinophysistoxin Port Underwood aquaculture niche partitioning thema EDItEUR::M Medicine and Nursing Blanco, Juan C. Reguera, Beatriz Dinophysis Toxins: Distribution, Fate in Shellfish and Impacts |
| title | Dinophysis Toxins: Distribution, Fate in Shellfish and Impacts |
| title_full | Dinophysis Toxins: Distribution, Fate in Shellfish and Impacts |
| title_fullStr | Dinophysis Toxins: Distribution, Fate in Shellfish and Impacts |
| title_full_unstemmed | Dinophysis Toxins: Distribution, Fate in Shellfish and Impacts |
| title_short | Dinophysis Toxins: Distribution, Fate in Shellfish and Impacts |
| title_sort | dinophysis toxins distribution fate in shellfish and impacts |
| topic | R5-920 RA1190-1270 WitOMI analysis n/a DST accumulation mussel dinophysistoxins depuration human health pectenotoxins (PTXs) cryptophytes Mesodinium dinophysis compartmentalization resistance Japanese scallop surf clam HAB monitoring toxins organic matter OMI analysis PTXs time-series Diarrhetic shellfish toxins predator-prey preferences immunity okadaic acid physical–biological interactions defense digestion Dinophysis harmful algal blooms pectenotoxin El Niño Southern Oscillation lysate suspended particulate matter (SPM) D. caudata mixotrophic cultures Mytilus galloprovincialis bivalves diarrhetic shellfish poisoning biotransformation Mesodinium cf. rubrum RNA-Seq DST esterification Mesodinium rubrum statistical analysis seasonality mass culture conditions D. acuminata-complex Argopecten purpuratus harmful algal bloom pipis (Plebidonax deltoides) DTX-2 Reloncaví Fjord pectenotoxins deep sequencing climatic anomaly Brazil qPCR high throughput sequencing DSP accumulation LC/MS/MS Protoceratium reticulatum shellfish toxicity transcriptomic response New Zealand blooms trophic transfer metabolism bacterial community kinetics marine biotoxins diarrhetic shellfish toxins bivalve shellfish Diarrhetic Shellfish Toxins (DST) diarrhetic shellfish toxins (DST) Scotland Dinophysis acuminata DSP toxins toxin accumulation Southern Annual Mode Diarrheic Shellfish Poisoning Dinophysis toxins OA marine toxins toxin vectors wild harvest Dinophysis acuta Sydney rock oyster (Saccostrea glomerata) Argopecten irradians dinophysistoxin Port Underwood aquaculture niche partitioning thema EDItEUR::M Medicine and Nursing |
| topic_facet | R5-920 RA1190-1270 WitOMI analysis n/a DST accumulation mussel dinophysistoxins depuration human health pectenotoxins (PTXs) cryptophytes Mesodinium dinophysis compartmentalization resistance Japanese scallop surf clam HAB monitoring toxins organic matter OMI analysis PTXs time-series Diarrhetic shellfish toxins predator-prey preferences immunity okadaic acid physical–biological interactions defense digestion Dinophysis harmful algal blooms pectenotoxin El Niño Southern Oscillation lysate suspended particulate matter (SPM) D. caudata mixotrophic cultures Mytilus galloprovincialis bivalves diarrhetic shellfish poisoning biotransformation Mesodinium cf. rubrum RNA-Seq DST esterification Mesodinium rubrum statistical analysis seasonality mass culture conditions D. acuminata-complex Argopecten purpuratus harmful algal bloom pipis (Plebidonax deltoides) DTX-2 Reloncaví Fjord pectenotoxins deep sequencing climatic anomaly Brazil qPCR high throughput sequencing DSP accumulation LC/MS/MS Protoceratium reticulatum shellfish toxicity transcriptomic response New Zealand blooms trophic transfer metabolism bacterial community kinetics marine biotoxins diarrhetic shellfish toxins bivalve shellfish Diarrhetic Shellfish Toxins (DST) diarrhetic shellfish toxins (DST) Scotland Dinophysis acuminata DSP toxins toxin accumulation Southern Annual Mode Diarrheic Shellfish Poisoning Dinophysis toxins OA marine toxins toxin vectors wild harvest Dinophysis acuta Sydney rock oyster (Saccostrea glomerata) Argopecten irradians dinophysistoxin Port Underwood aquaculture niche partitioning thema EDItEUR::M Medicine and Nursing |
| url | 42539 |
| work_keys_str_mv | AT blancojuanc dinophysistoxinsdistributionfateinshellfishandimpacts AT reguerabeatriz dinophysistoxinsdistributionfateinshellfishandimpacts |