DNA Replication Controls
The conditions for DNA replication are not ideal, owing to endogenous and exogenous replication stresses that lead to arrest of the replication fork. Arrested forks are among the most serious threats to genomic integrity because they can break or rearrange, leading to genomic instability, which is a...
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| Materialtyp: | Online |
| Språk: | engelska |
| Utgiven: |
MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Länkar: | 24951 |
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| _version_ | 1869522532698161152 |
|---|---|
| author | Eishi Noguchi (Ed.) |
| author_browse | Eishi Noguchi (Ed.) |
| author_facet | Eishi Noguchi (Ed.) |
| author_sort | Eishi Noguchi (Ed.) |
| collection | Directory of Open Access Books |
| description | The conditions for DNA replication are not ideal, owing to endogenous and exogenous replication stresses that lead to arrest of the replication fork. Arrested forks are among the most serious threats to genomic integrity because they can break or rearrange, leading to genomic instability, which is a hallmark of cancers and aging-related disorders. |
| format | Online |
| id | doab-20.500.12854ir-45329 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-453292024-09-16T10:19:58Z DNA Replication Controls Eishi Noguchi (Ed.) QH301-705.5 DNA helicase DNA replication replication stress replication checkpoint DNA polymerase telomere replication cancer genomic instability DNA repair replisome translesion synthesis thema EDItEUR::P Mathematics and Science::PS Biology, life sciences The conditions for DNA replication are not ideal, owing to endogenous and exogenous replication stresses that lead to arrest of the replication fork. Arrested forks are among the most serious threats to genomic integrity because they can break or rearrange, leading to genomic instability, which is a hallmark of cancers and aging-related disorders. 2021-02-11T11:37:38Z 2021-02-11T11:37:38Z 2018-01-02 15:17:59 2017 book 24951 9783038425694 9783038425687 https://directory.doabooks.org/handle/20.500.12854/45329 eng image/jpeg Attribution-NonCommercial-NoDerivatives 4.0 International http://www.mdpi.com/books/pdfview/book/453 http://www.mdpi.com/books/pdfview/book/453 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03842-569-4 10.3390/books978-3-03842-569-4 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038425694 9783038425687 X, 304 open access |
| spellingShingle | QH301-705.5 DNA helicase DNA replication replication stress replication checkpoint DNA polymerase telomere replication cancer genomic instability DNA repair replisome translesion synthesis thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Eishi Noguchi (Ed.) DNA Replication Controls |
| title | DNA Replication Controls |
| title_full | DNA Replication Controls |
| title_fullStr | DNA Replication Controls |
| title_full_unstemmed | DNA Replication Controls |
| title_short | DNA Replication Controls |
| title_sort | dna replication controls |
| topic | QH301-705.5 DNA helicase DNA replication replication stress replication checkpoint DNA polymerase telomere replication cancer genomic instability DNA repair replisome translesion synthesis thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | QH301-705.5 DNA helicase DNA replication replication stress replication checkpoint DNA polymerase telomere replication cancer genomic instability DNA repair replisome translesion synthesis thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | 24951 |
| work_keys_str_mv | AT eishinoguchied dnareplicationcontrols |