ECG Based Analysis of the Ventricular Repolarisation in the Human Heart
ECG recordings provide diagnostic relevant information on the de- and repolarisation sequences of the heart. A modification of the repolarisation sequence is assumed to cause Torsades de Pointes. Especially drug induced effects on the repolarisation processes are in focus, since some non-cardiac dru...
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| Päätekijä: | |
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| Aineistotyyppi: | Online |
| Kieli: | englanti |
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KIT Scientific Publishing
2021
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| Aiheet: | |
| Linkit: | 34536 |
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| _version_ | 1869525725316382720 |
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| author | Baas, Tobias |
| author_browse | Baas, Tobias |
| author_facet | Baas, Tobias |
| author_sort | Baas, Tobias |
| collection | Directory of Open Access Books |
| description | ECG recordings provide diagnostic relevant information on the de- and repolarisation sequences of the heart. A modification of the repolarisation sequence is assumed to cause Torsades de Pointes. Especially drug induced effects on the repolarisation processes are in focus, since some non-cardiac drugs have been associated with sudden cardiac death in the 1990s. The analysis of the ventricular repolarisation using a set of parameters depicting the morphology of the T-wave is introduced in this work. Therefore, new methods of fully automatic patient-specific QRS detection, beat classification and precise T-wave delineation are presented. Using these methods, medical studies are investigated regarding the modification of the T-wave by different compounds. Also the impact of the heart rate on the morphology of the T-wave is part of this research.The reliable identification of ventricular ectopic beats allows an analysis of the influence of these beats on subsequent heart beats. It turned out that the morphology of subsequent heart beats can significantly be changed. This might give new information on the proarrythmical risk of ventricular ectopic beats. |
| format | Online |
| id | doab-20.500.12854ir-45668 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | KIT Scientific Publishing |
| publisherStr | KIT Scientific Publishing |
| record_format | ojs |
| spelling | doab-20.500.12854ir-456682024-04-09T23:15:29Z ECG Based Analysis of the Ventricular Repolarisation in the Human Heart Baas, Tobias T1-995 QT interval QT prolongation T wave Repolarisation HRT thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ECG recordings provide diagnostic relevant information on the de- and repolarisation sequences of the heart. A modification of the repolarisation sequence is assumed to cause Torsades de Pointes. Especially drug induced effects on the repolarisation processes are in focus, since some non-cardiac drugs have been associated with sudden cardiac death in the 1990s. The analysis of the ventricular repolarisation using a set of parameters depicting the morphology of the T-wave is introduced in this work. Therefore, new methods of fully automatic patient-specific QRS detection, beat classification and precise T-wave delineation are presented. Using these methods, medical studies are investigated regarding the modification of the T-wave by different compounds. Also the impact of the heart rate on the morphology of the T-wave is part of this research.The reliable identification of ventricular ectopic beats allows an analysis of the influence of these beats on subsequent heart beats. It turned out that the morphology of subsequent heart beats can significantly be changed. This might give new information on the proarrythmical risk of ventricular ectopic beats. 2021-02-11T11:57:20Z 2021-02-11T11:57:20Z 2019-07-30 20:01:58 2012 book 34536 18645933 9783866448827 https://directory.doabooks.org/handle/20.500.12854/45668 eng Karlsruhe transactions on biomedical engineering / Ed.: Karlsruhe Institute of Technology / Institute of Biomedical Engineering image/jpeg Attribution-NonCommercial-NoDerivatives 4.0 International https://www.ksp.kit.edu/9783866448827 KIT Scientific Publishing 10.5445/KSP/1000028834 10.5445/KSP/1000028834 68fffc18-8f7b-44fa-ac7e-0b7d7d979bd2 9783866448827 XX, 224 p. open access |
| spellingShingle | T1-995 QT interval QT prolongation T wave Repolarisation HRT thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues Baas, Tobias ECG Based Analysis of the Ventricular Repolarisation in the Human Heart |
| title | ECG Based Analysis of the Ventricular Repolarisation in the Human Heart |
| title_full | ECG Based Analysis of the Ventricular Repolarisation in the Human Heart |
| title_fullStr | ECG Based Analysis of the Ventricular Repolarisation in the Human Heart |
| title_full_unstemmed | ECG Based Analysis of the Ventricular Repolarisation in the Human Heart |
| title_short | ECG Based Analysis of the Ventricular Repolarisation in the Human Heart |
| title_sort | ecg based analysis of the ventricular repolarisation in the human heart |
| topic | T1-995 QT interval QT prolongation T wave Repolarisation HRT thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues |
| topic_facet | T1-995 QT interval QT prolongation T wave Repolarisation HRT thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues |
| url | 34536 |
| work_keys_str_mv | AT baastobias ecgbasedanalysisoftheventricularrepolarisationinthehumanheart |