Electrochemical Immunosensors and Aptasensors
The possibility to integrate biorecognition elements into electrochemical detection systems has opened the way to a new class of powerful analytical devices named electrochemical (EC) biosensors. The first EC biosensors employed enzymes as recognition elements; however this limited their application...
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| Materialtyp: | Online |
| Språk: | engelska |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Länkar: | 22200 |
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| _version_ | 1869525828846485504 |
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| author | Paolo Ugo (Ed.) Ligia Moretto (Ed.) |
| author_browse | Ligia Moretto (Ed.) Paolo Ugo (Ed.) |
| author_facet | Paolo Ugo (Ed.) Ligia Moretto (Ed.) |
| author_sort | Paolo Ugo (Ed.) |
| collection | Directory of Open Access Books |
| description | The possibility to integrate biorecognition elements into electrochemical detection systems has opened the way to a new class of powerful analytical devices named electrochemical (EC) biosensors. The first EC biosensors employed enzymes as recognition elements; however this limited their application to redox enzymes and natural or artificial redox substrates or inhibitors. Broadening this to include non-electroactive analytes was later possible thanks to the development of affinity sensors in which specific interactions between biomolecules are exploited for developing highly selective and sensitive biosensors. Presently, the combination of the exceptional molecular recognition capabilities of antibodies and aptamers with the sensitivity, low cost, practicality of use and handiness of electrochemical devices is leading to an impressive development of EC immunosensors and aptasensors that are potentially suitable to detect a wide range of analytes, following a path that is moving alongside the most recent advances in proteomics. Interestingly, with continued improvements and refinements in EC immunosensors based on the use of labels, together with intrinsically electroactive, or those with the ability to interact with electroactive molecules, a new generation of label-free sensors is being developed. This Special Issue takes stock of the state of the art and identifies prospects for EC immuno- and aptasensors, both labeled and label-free. Emphasis is placed on analytical applications for the rapid detection of disease markers and for toxicological and food analyses. |
| format | Online |
| id | doab-20.500.12854ir-46130 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-461302024-04-05T12:39:40Z Electrochemical Immunosensors and Aptasensors Paolo Ugo (Ed.) Ligia Moretto (Ed.) QD1-999 Immuno-test Electrochemical impedance Electrochemical sensors Aptamers Amperometry Voltammetry Functional electrodes Biosensors Protein detection thema EDItEUR::P Mathematics and Science::PN Chemistry The possibility to integrate biorecognition elements into electrochemical detection systems has opened the way to a new class of powerful analytical devices named electrochemical (EC) biosensors. The first EC biosensors employed enzymes as recognition elements; however this limited their application to redox enzymes and natural or artificial redox substrates or inhibitors. Broadening this to include non-electroactive analytes was later possible thanks to the development of affinity sensors in which specific interactions between biomolecules are exploited for developing highly selective and sensitive biosensors. Presently, the combination of the exceptional molecular recognition capabilities of antibodies and aptamers with the sensitivity, low cost, practicality of use and handiness of electrochemical devices is leading to an impressive development of EC immunosensors and aptasensors that are potentially suitable to detect a wide range of analytes, following a path that is moving alongside the most recent advances in proteomics. Interestingly, with continued improvements and refinements in EC immunosensors based on the use of labels, together with intrinsically electroactive, or those with the ability to interact with electroactive molecules, a new generation of label-free sensors is being developed. This Special Issue takes stock of the state of the art and identifies prospects for EC immuno- and aptasensors, both labeled and label-free. Emphasis is placed on analytical applications for the rapid detection of disease markers and for toxicological and food analyses. 2021-02-11T12:19:49Z 2021-02-11T12:19:49Z 2017-06-02 09:40:26 2017 book 22200 9783038424062 9783038424079 https://directory.doabooks.org/handle/20.500.12854/46130 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International http://www.mdpi.com/books/pdfview/book/305 http://www.mdpi.com/books/pdfview/book/305 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03842-407-9 10.3390/books978-3-03842-407-9 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038424062 9783038424079 VIII, 178 open access |
| spellingShingle | QD1-999 Immuno-test Electrochemical impedance Electrochemical sensors Aptamers Amperometry Voltammetry Functional electrodes Biosensors Protein detection thema EDItEUR::P Mathematics and Science::PN Chemistry Paolo Ugo (Ed.) Ligia Moretto (Ed.) Electrochemical Immunosensors and Aptasensors |
| title | Electrochemical Immunosensors and Aptasensors |
| title_full | Electrochemical Immunosensors and Aptasensors |
| title_fullStr | Electrochemical Immunosensors and Aptasensors |
| title_full_unstemmed | Electrochemical Immunosensors and Aptasensors |
| title_short | Electrochemical Immunosensors and Aptasensors |
| title_sort | electrochemical immunosensors and aptasensors |
| topic | QD1-999 Immuno-test Electrochemical impedance Electrochemical sensors Aptamers Amperometry Voltammetry Functional electrodes Biosensors Protein detection thema EDItEUR::P Mathematics and Science::PN Chemistry |
| topic_facet | QD1-999 Immuno-test Electrochemical impedance Electrochemical sensors Aptamers Amperometry Voltammetry Functional electrodes Biosensors Protein detection thema EDItEUR::P Mathematics and Science::PN Chemistry |
| url | 22200 |
| work_keys_str_mv | AT paolougoed electrochemicalimmunosensorsandaptasensors AT ligiamorettoed electrochemicalimmunosensorsandaptasensors |