Electrospun and Electrosprayed Formulations for Drug Delivery
This book is comprised of important reviews and cutting-edge original research papers concerning electrospun and electrosprayed formulations in drug delivery. Electrospinning and electrospraying have, in recent years, attracted increasing attention in the pharmaceutical sector, with research in the...
محفوظ في:
| المؤلفون الرئيسيون: | , |
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| التنسيق: | Online |
| اللغة: | الإنجليزية |
| منشور في: |
MDPI - Multidisciplinary Digital Publishing Institute
2021
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| الموضوعات: | |
| الوصول للمادة أونلاين: | 33725 |
| الوسوم: |
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| _version_ | 1869514991008219136 |
|---|---|
| author | Williams, Gareth R. Blagbrough, Ian S. |
| author_browse | Blagbrough, Ian S. Williams, Gareth R. |
| author_facet | Williams, Gareth R. Blagbrough, Ian S. |
| author_sort | Williams, Gareth R. |
| collection | Directory of Open Access Books |
| description | This book is comprised of important reviews and cutting-edge original research papers concerning electrospun and electrosprayed formulations in drug delivery. Electrospinning and electrospraying have, in recent years, attracted increasing attention in the pharmaceutical sector, with research in the area advancing rapidly. It is now possible to prepare extremely complex systems using multi-fluid processes, and to increase production rates to an industrial scale. Electrospun formulations can be produced under GMP conditions and are in clinical trials. In this volume, we explore a range of topics around electrospinning and electrospraying in controlled drug delivery. Four reviews cover the exciting potential of cyclodextrin-containing fibers and the many potential biomedical applications of electrospun fibers. The use of electrospinning to prepare amorphous systems and improve the dissolution rate and solubility of poorly soluble active ingredients is addressed, and the possibilities of such materials in tissue engineering are comprehensively covered. The six original research papers cover the effect of molecular properties on API release from Eudragit-based electrospun fibers; ferulic acid solid dispersions; electrospun medicines to treat psoriasis; scale up of electrospinning and its use to produce low-dose tablets; transepithelial permeation of drugs released from electrospun fibers, and the possibilities for the synergistic chemophotothermal treatment of cancer. |
| format | Online |
| id | doab-20.500.12854ir-46161 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-461612024-03-30T23:21:41Z Electrospun and Electrosprayed Formulations for Drug Delivery Williams, Gareth R. Blagbrough, Ian S. R5-920 RM1-950 tissue engineering cyclodextrin permeability poly (vinylpyrrolidone-co-vinyl acetate) crystalline antibacterial drug delivery homogenization capsaicin combination therapy high-shear mixing cyclodextrin-inclusion complexes amorphous high-speed electrospinning PMVE/MA aqueous solubility enhancement sieve analysis Raman mapping Eudragit nanofibers psoriasis PCL essential oils parameters antibiotics xanthan gum carvedilol amorphous composite coaxial electrospinning insoluble drug NIR-triggered drug release fast dissolution electrospinning oral drug delivery electrospun nanofibers poly-cyclodextrin TRPV1 gallic acid solid dispersion photothermal therapy drug release applications thema EDItEUR::M Medicine and Nursing This book is comprised of important reviews and cutting-edge original research papers concerning electrospun and electrosprayed formulations in drug delivery. Electrospinning and electrospraying have, in recent years, attracted increasing attention in the pharmaceutical sector, with research in the area advancing rapidly. It is now possible to prepare extremely complex systems using multi-fluid processes, and to increase production rates to an industrial scale. Electrospun formulations can be produced under GMP conditions and are in clinical trials. In this volume, we explore a range of topics around electrospinning and electrospraying in controlled drug delivery. Four reviews cover the exciting potential of cyclodextrin-containing fibers and the many potential biomedical applications of electrospun fibers. The use of electrospinning to prepare amorphous systems and improve the dissolution rate and solubility of poorly soluble active ingredients is addressed, and the possibilities of such materials in tissue engineering are comprehensively covered. The six original research papers cover the effect of molecular properties on API release from Eudragit-based electrospun fibers; ferulic acid solid dispersions; electrospun medicines to treat psoriasis; scale up of electrospinning and its use to produce low-dose tablets; transepithelial permeation of drugs released from electrospun fibers, and the possibilities for the synergistic chemophotothermal treatment of cancer. 2021-02-11T12:20:46Z 2021-02-11T12:20:46Z 2019-06-26 10:09:00 2019 book 33725 9783038979135 9783038979128 https://directory.doabooks.org/handle/20.500.12854/46161 eng image/jpeg Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/1346 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03897-913-5 10.3390/books978-3-03897-913-5 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038979135 9783038979128 190 open access |
| spellingShingle | R5-920 RM1-950 tissue engineering cyclodextrin permeability poly (vinylpyrrolidone-co-vinyl acetate) crystalline antibacterial drug delivery homogenization capsaicin combination therapy high-shear mixing cyclodextrin-inclusion complexes amorphous high-speed electrospinning PMVE/MA aqueous solubility enhancement sieve analysis Raman mapping Eudragit nanofibers psoriasis PCL essential oils parameters antibiotics xanthan gum carvedilol amorphous composite coaxial electrospinning insoluble drug NIR-triggered drug release fast dissolution electrospinning oral drug delivery electrospun nanofibers poly-cyclodextrin TRPV1 gallic acid solid dispersion photothermal therapy drug release applications thema EDItEUR::M Medicine and Nursing Williams, Gareth R. Blagbrough, Ian S. Electrospun and Electrosprayed Formulations for Drug Delivery |
| title | Electrospun and Electrosprayed Formulations for Drug Delivery |
| title_full | Electrospun and Electrosprayed Formulations for Drug Delivery |
| title_fullStr | Electrospun and Electrosprayed Formulations for Drug Delivery |
| title_full_unstemmed | Electrospun and Electrosprayed Formulations for Drug Delivery |
| title_short | Electrospun and Electrosprayed Formulations for Drug Delivery |
| title_sort | electrospun and electrosprayed formulations for drug delivery |
| topic | R5-920 RM1-950 tissue engineering cyclodextrin permeability poly (vinylpyrrolidone-co-vinyl acetate) crystalline antibacterial drug delivery homogenization capsaicin combination therapy high-shear mixing cyclodextrin-inclusion complexes amorphous high-speed electrospinning PMVE/MA aqueous solubility enhancement sieve analysis Raman mapping Eudragit nanofibers psoriasis PCL essential oils parameters antibiotics xanthan gum carvedilol amorphous composite coaxial electrospinning insoluble drug NIR-triggered drug release fast dissolution electrospinning oral drug delivery electrospun nanofibers poly-cyclodextrin TRPV1 gallic acid solid dispersion photothermal therapy drug release applications thema EDItEUR::M Medicine and Nursing |
| topic_facet | R5-920 RM1-950 tissue engineering cyclodextrin permeability poly (vinylpyrrolidone-co-vinyl acetate) crystalline antibacterial drug delivery homogenization capsaicin combination therapy high-shear mixing cyclodextrin-inclusion complexes amorphous high-speed electrospinning PMVE/MA aqueous solubility enhancement sieve analysis Raman mapping Eudragit nanofibers psoriasis PCL essential oils parameters antibiotics xanthan gum carvedilol amorphous composite coaxial electrospinning insoluble drug NIR-triggered drug release fast dissolution electrospinning oral drug delivery electrospun nanofibers poly-cyclodextrin TRPV1 gallic acid solid dispersion photothermal therapy drug release applications thema EDItEUR::M Medicine and Nursing |
| url | 33725 |
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