Endoplasmic reticulum - shape and function in stress translation
The endoplasmic reticulum (ER) is a manufacturing unit in eukaryotic cells required for the synthesis of proteins, lipids, metabolites and hormones. Besides supporting cellular signalling networks by its anabolic function, the ER on its own or in communication with other organelles directly initiate...
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| Formato: | Online |
| Idioma: | inglês |
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Frontiers Media SA
2021
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| Acesso em linha: | 18674 |
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| _version_ | 1869531012231331840 |
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| author | Federica Brandizzi Stephen H Howell Patrick Schafer Lorenzo Frigerio |
| author_browse | Federica Brandizzi Lorenzo Frigerio Patrick Schafer Stephen H Howell |
| author_facet | Federica Brandizzi Stephen H Howell Patrick Schafer Lorenzo Frigerio |
| author_sort | Federica Brandizzi |
| collection | Directory of Open Access Books |
| description | The endoplasmic reticulum (ER) is a manufacturing unit in eukaryotic cells required for the synthesis of proteins, lipids, metabolites and hormones. Besides supporting cellular signalling networks by its anabolic function, the ER on its own or in communication with other organelles directly initiates signalling processes of physiological significance. Based on the intimate and immediate involvement in stress signalling the ER is considered as sensory organelle on which cells strongly rely to effectively translate environmental cues into adaptive stress responses. The transcellular distribution of the ER providing comprehensive cell-to-cell connections in multicellular organisms probably allows a concerted action of cell alliances and tissue areas towards environmental constraints. At the cellular level, stress adaptation correlates with the capability of the ER machinery to synthesise proteins participating in stress signalling as well as in the activation of ER membrane localised proteins to start cell-protective signalling processes. Importantly, depending on the stress insult, the ER either supports protective strategies or initiates cell death programmes. Recent, genetic, molecular and cell biological studies have drawn an initial picture of underlying signalling events activated by ER membrane localised proteins. In this Research Topic, we provided a platform for articles describing research on ER morphology and metabolism with a focus on stress translation. The Research Topic is sub-divided into the following sections: 1. ER in stress signalling and adaptation 2. ER structure and biosynthetic functions 3. Regulation of protein processing 4. Regulation of programmed cell death |
| format | Online |
| id | doab-20.500.12854ir-46349 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-463492024-04-05T17:31:21Z Endoplasmic reticulum - shape and function in stress translation Federica Brandizzi Stephen H Howell Patrick Schafer Lorenzo Frigerio QK1-989 Q1-390 Myosins cysteine endopeptidase ER associated degradation Unfolded Protein Response ER bodies programmed cell death bZIP transcription factors caspase thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences The endoplasmic reticulum (ER) is a manufacturing unit in eukaryotic cells required for the synthesis of proteins, lipids, metabolites and hormones. Besides supporting cellular signalling networks by its anabolic function, the ER on its own or in communication with other organelles directly initiates signalling processes of physiological significance. Based on the intimate and immediate involvement in stress signalling the ER is considered as sensory organelle on which cells strongly rely to effectively translate environmental cues into adaptive stress responses. The transcellular distribution of the ER providing comprehensive cell-to-cell connections in multicellular organisms probably allows a concerted action of cell alliances and tissue areas towards environmental constraints. At the cellular level, stress adaptation correlates with the capability of the ER machinery to synthesise proteins participating in stress signalling as well as in the activation of ER membrane localised proteins to start cell-protective signalling processes. Importantly, depending on the stress insult, the ER either supports protective strategies or initiates cell death programmes. Recent, genetic, molecular and cell biological studies have drawn an initial picture of underlying signalling events activated by ER membrane localised proteins. In this Research Topic, we provided a platform for articles describing research on ER morphology and metabolism with a focus on stress translation. The Research Topic is sub-divided into the following sections: 1. ER in stress signalling and adaptation 2. ER structure and biosynthetic functions 3. Regulation of protein processing 4. Regulation of programmed cell death 2021-02-11T12:30:59Z 2021-02-11T12:30:59Z 2016-03-10 08:14:32 2015 book 18674 16648714 9782889193448 https://directory.doabooks.org/handle/20.500.12854/46349 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Endoplasmic_reticulum_%E2%80%93_shape_and_function_in_stress_translation/513#nogo http://journal.frontiersin.org/researchtopic/1719/endoplasmic-reticulum---shape-and-function-in-stress-translation Frontiers Media SA 10.3389/978-2-88919-344-8 10.3389/978-2-88919-344-8 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889193448 110 open access |
| spellingShingle | QK1-989 Q1-390 Myosins cysteine endopeptidase ER associated degradation Unfolded Protein Response ER bodies programmed cell death bZIP transcription factors caspase thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences Federica Brandizzi Stephen H Howell Patrick Schafer Lorenzo Frigerio Endoplasmic reticulum - shape and function in stress translation |
| title | Endoplasmic reticulum - shape and function in stress translation |
| title_full | Endoplasmic reticulum - shape and function in stress translation |
| title_fullStr | Endoplasmic reticulum - shape and function in stress translation |
| title_full_unstemmed | Endoplasmic reticulum - shape and function in stress translation |
| title_short | Endoplasmic reticulum - shape and function in stress translation |
| title_sort | endoplasmic reticulum shape and function in stress translation |
| topic | QK1-989 Q1-390 Myosins cysteine endopeptidase ER associated degradation Unfolded Protein Response ER bodies programmed cell death bZIP transcription factors caspase thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences |
| topic_facet | QK1-989 Q1-390 Myosins cysteine endopeptidase ER associated degradation Unfolded Protein Response ER bodies programmed cell death bZIP transcription factors caspase thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences |
| url | 18674 |
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